{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T06:05:25Z","timestamp":1780725925898,"version":"3.54.1"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2026,5,31]]},"abstract":"<jats:p>There is a need to understand how smoking alters salivary biomarkers and periodontal disease severity. Therefore, it is of interest to evaluate salivary biomarkers in smokers and non-smokers with chronic periodontitis. Hence, a cross-sectional design included 100 subjects, with clinical parameters and salivary biomarkers analyzed using ELISA and SPSS. Smokers showed significantly higher periodontal parameters and elevated inflammatory and oxidative stress markers, with reduced antioxidant levels. Thus, we show salivary biomarkers as reliable non-invasive indicators for monitoring periodontal disease, especially in smokers. Salivary biomarkers can serve as effective, non-invasive tools for diagnosis and disease monitoring, particularly in smokers.<\/jats:p>","DOI":"10.6026\/973206300222828","type":"journal-article","created":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T05:50:37Z","timestamp":1780725037000},"page":"2828-2832","source":"Crossref","is-referenced-by-count":0,"title":["A comparative study of salivary biomarkers for periodontal disease among smokers and non-smokers"],"prefix":"10.6026","volume":"22","author":[{"given":"Anusha","family":"Pulluri","sequence":"first","affiliation":[{"name":"Department of Dentistry, Sri Sai College of Dental Surgery, Moinabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saloni","family":"Tomar","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Kennedy Dental Center, Union City, NJ 07087, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nabiha Naureen","family":"Syeda","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Sri Balaji Dental College, Moinabad, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence K","family":"Priya","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, Neuro and Dental Care, Secunderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaz Rachel","family":"Reemal","sequence":"additional","affiliation":[{"name":"Department of Dentistry, KVG Dental College Hospital, Sullia, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naseemoon","family":"Shaik","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry, MNR Dental College and Hospital, Sangareddy, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4070","published-online":{"date-parts":[[2026,5,31]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T05:50:38Z","timestamp":1780725038000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/022\/973206300222828.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,31]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,5,31]]},"published-print":{"date-parts":[[2026,5,31]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300222828","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,31]]}}}