{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:01:02Z","timestamp":1780729262396,"version":"3.54.1"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2026,5,31]]},"abstract":"<jats:p>Chronic kidney disease (CKD) is a major microvascular complication of diabetes in rural India, where access to diagnostic facilities is limited. 24-hour urine protein estimation, through the reference method is impractical for community screening. Therefore, it is of interest to evaluate the diagnostic accuracy of urinary albumin-to-creatinine ratio (UACR) for CKD screening among 201 known diabetic individuals from rural Nagpur. Elevated UACR was observed in 99% of participants, whereas 59% had abnormal 24-hour urine protein excretion. UACR demonstrated 100% sensitivity but low specificity (4%), with an overall diagnostic accuracy of 60% and a negative predictive value of 100%. UACR correlated significantly with glycaemic indices, eGFR and proteinuria and its screening utility improves when combined with serum creatinine and eGFR in resource-limited community settings.<\/jats:p>","DOI":"10.6026\/973206300222863","type":"journal-article","created":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T06:28:28Z","timestamp":1780727308000},"page":"2863-2868","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic accuracy of UACR in CKD screening among diabetics: A community study"],"prefix":"10.6026","volume":"22","author":[{"given":"Utsav","family":"Haldar","sequence":"first","affiliation":[{"name":"Department of Biochemistry, All India Institute of Medical Sciences, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niranjan","family":"Gopal","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, All India Institute of Medical Sciences, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anand","family":"Chellappan","sequence":"additional","affiliation":[{"name":"Department of Nephrology, All India Institute of Medical Sciences, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dnyanesh","family":"Amle","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, All India Institute of Medical Sciences, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nandeesh","family":"Kuravatti","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, All India Institute of Medical Sciences, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, All India Institute of Medical Sciences, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyoti E.","family":"John","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, All India Institute of Medical Sciences, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepa","family":"Telgote","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, All India Institute of Medical Sciences, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4070","published-online":{"date-parts":[[2026,5,31]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T06:28:30Z","timestamp":1780727310000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/022\/973206300222863.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,31]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,5,31]]},"published-print":{"date-parts":[[2026,5,31]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300222863","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,31]]}}}