{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T12:45:29Z","timestamp":1782650729277,"version":"3.54.5"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2026,6,30]]},"abstract":"<jats:p>Early and accurate prediction of severity in acute pancreatitis remains a major clinical challenge, particularly in resource-limited\nsettings. Hence, this cross-sectional study evaluated 100 patients to assess the prognostic value of the CRP\/Albumin ratio (CAR) in\ncomparison with BISAP and other parameters. Disease severity was mild in 40%, moderate in 30% and severe in 30%, with ICU\nadmission in 23% and overall mortality of 5%, increasing with severity. Non-survivors had significantly higher age (62.6 \u00b1 7.09 vs\n40.41 \u00b1 13.66 years), urea (78.72 \u00b1 66.08 vs 24.09 \u00b1 13.99 mg\/dL), creatinine (2.69 \u00b1 1.68 vs 0.84 \u00b1 0.43 mg\/dL), CRP (182.61 \u00b1 141.55 vs\n75.98 \u00b1 82.76 mg\/L), CAR (107.18 \u00b1 106.30 vs 28.09 \u00b1 38.10) and BISAP scores (4.6 \u00b1 0.55 vs 0.85 \u00b1 0.99), along with lower albumin\nlevels (2.11 \u00b1 0.87 vs 3.20 \u00b1 0.98 g\/dL). Thus, BISAP showed the highest predictive accuracy (AUC = 1.000), followed by creatinine\n(0.985), age (0.952) and CAR (0.930).<\/jats:p>","DOI":"10.6026\/973206300223521","type":"journal-article","created":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T12:25:16Z","timestamp":1782649516000},"page":"3521-3526","source":"Crossref","is-referenced-by-count":0,"title":["C - reactive protein to albumin ratio as predictor of severity and outcome in acute pancreatitis"],"prefix":"10.6026","volume":"22","author":[{"given":"Umesh Pratap","family":"Singh","sequence":"first","affiliation":[{"name":"Department of General Medicine, Shyam Shah Medical College and Associated Sanjay Gandhi Memorial Hospital, Rewa, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4070","published-online":{"date-parts":[[2026,6,30]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T12:25:24Z","timestamp":1782649524000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/022\/973206300223521.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,30]]},"references-count":0,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2026,6,30]]},"published-print":{"date-parts":[[2026,6,30]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300223521","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,30]]}}}