{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T23:46:39Z","timestamp":1789429599261,"version":"build-2803163510"},"reference-count":30,"publisher":"Korean Society of Pediatric Endocrinology","issue":"4","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002462","name":"Chungnam National University","doi-asserted-by":"publisher","award":["#2012-1915"],"award-info":[{"award-number":["#2012-1915"]}],"id":[{"id":"10.13039\/501100002462","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["Ann Pediatr Endocrinol Metab"],"published-print":{"date-parts":[[2016]]},"DOI":"10.6065\/apem.2016.21.4.199","type":"journal-article","created":{"date-parts":[[2017,2,2]],"date-time":"2017-02-02T19:26:35Z","timestamp":1486063595000},"page":"199","update-policy":"https:\/\/doi.org\/10.6065\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Leptin and adiponectin levels in girls with central precocious puberty before and during GnRH agonist treatment"],"prefix":"10.6065","volume":"21","author":[{"given":"Jae Won","family":"Yoo","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Chungnam National University School of Medicine, Daejeon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun Woo","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Chungnam National University School of Medicine, Daejeon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5297-5913","authenticated-orcid":false,"given":"Han Hyuk","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Chungnam National University School of Medicine, Daejeon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4096","reference":[{"key":"10.6065\/apem.2016.21.4.199_ref1","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1210\/jc.2013-1024","volume":"98","author":"Fuqua","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"10.6065\/apem.2016.21.4.199_ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/MED.0b013e3283207937","volume":"16","author":"DiVall","year":"2009","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"10.6065\/apem.2016.21.4.199_ref3","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1542\/peds.108.2.347","volume":"108","author":"Kaplowitz","year":"2001","journal-title":"Pediatrics"},{"key":"10.6065\/apem.2016.21.4.199_ref4","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1210\/jc.2007-1216","volume":"93","author":"Pasquino","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.6065\/apem.2016.21.4.199_ref5","first-page":"27","volume":"53","author":"Ta\u015fcilar","year":"2011","journal-title":"Turk J Pediatr"},{"key":"10.6065\/apem.2016.21.4.199_ref6","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1038\/nm1195-1155","volume":"1","author":"Maffei","year":"1995","journal-title":"Nat Med"},{"key":"10.6065\/apem.2016.21.4.199_ref7","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s11154-013-9283-3","volume":"15","author":"Lee","year":"2014","journal-title":"Rev Endocr Metab Disord"},{"key":"10.6065\/apem.2016.21.4.199_ref8","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.cmet.2007.06.003","volume":"6","author":"Kubota","year":"2007","journal-title":"Cell Metab"},{"key":"10.6065\/apem.2016.21.4.199_ref9","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.mce.2015.12.022","volume":"423","author":"Bohlen","year":"2016","journal-title":"Mol Cell Endocrinol"},{"key":"10.6065\/apem.2016.21.4.199_ref10","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.yhbeh.2013.01.014","volume":"64","author":"Sanchez-Garrido","year":"2013","journal-title":"Horm Behav"},{"key":"10.6065\/apem.2016.21.4.199_ref11","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.peptides.2014.12.011","volume":"64","author":"Abac\u0131","year":"2015","journal-title":"Peptides"},{"key":"10.6065\/apem.2016.21.4.199_ref12","volume-title":"2007 Korean children and adolescents growth standard (commentary for the development of 2007 growth chart","author":"Korea Centers for Disease Control and Prevention, Division of Chronic Disease Surveillance, Committee for the Development of Growth Standard for Korean Children and Adolescents","year":"2007"},{"key":"10.6065\/apem.2016.21.4.199_ref13","first-page":"2904","volume":"82","author":"Blum","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"10.6065\/apem.2016.21.4.199_ref14","doi-asserted-by":"crossref","first-page":"e624","DOI":"10.1542\/peds.2006-2188","volume":"119","author":"Lee","year":"2007","journal-title":"Pediatrics"},{"key":"10.6065\/apem.2016.21.4.199_ref15","doi-asserted-by":"crossref","first-page":"3396","DOI":"10.1210\/en.2010-1415","volume":"152","author":"Castellano","year":"2011","journal-title":"Endocrinology"},{"key":"10.6065\/apem.2016.21.4.199_ref16","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1159\/000054666","volume":"74","author":"Cheung","year":"2001","journal-title":"Neuroendocrinology"},{"key":"10.6065\/apem.2016.21.4.199_ref17","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1046\/j.1365-2265.2003.01911.x","volume":"59","author":"Tommaselli","year":"2003","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.6065\/apem.2016.21.4.199_ref18","first-page":"278","volume":"46","author":"Su","year":"2005","journal-title":"Acta Paediatr Taiwan"},{"key":"10.6065\/apem.2016.21.4.199_ref19","first-page":"125","volume":"16","author":"Verrotti","year":"2003","journal-title":"Diabetes Nutr Metab"},{"key":"10.6065\/apem.2016.21.4.199_ref20","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0969-8043(97)00076-6","volume":"49","author":"M\u00f8lgaard","year":"1998","journal-title":"Appl Radiat Isot"},{"issue":"4 Pt 1","key":"10.6065\/apem.2016.21.4.199_ref21","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1542\/peds.111.4.815","volume":"111","author":"Davison","year":"2003","journal-title":"Pediatrics"},{"key":"10.6065\/apem.2016.21.4.199_ref22","first-page":"370","volume":"83","author":"Boot","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.6065\/apem.2016.21.4.199_ref23","doi-asserted-by":"crossref","first-page":"3189","DOI":"10.1210\/jc.2007-0231","volume":"92","author":"S\u00f8rensen","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"10.6065\/apem.2016.21.4.199_ref24","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.2337\/db14-0744","volume":"64","author":"Landgraf","year":"2015","journal-title":"Diabetes"},{"key":"10.6065\/apem.2016.21.4.199_ref25","doi-asserted-by":"crossref","first-page":"3736","DOI":"10.1210\/jc.2010-0731","volume":"95","author":"S\u00f8rensen","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.6065\/apem.2016.21.4.199_ref26","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1016\/j.metabol.2006.05.010","volume":"55","author":"Inoue","year":"2006","journal-title":"Metabolism"},{"key":"10.6065\/apem.2016.21.4.199_ref27","doi-asserted-by":"crossref","first-page":"4053","DOI":"10.1210\/jc.2004-0303","volume":"89","author":"B\u00f6ttner","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.6065\/apem.2016.21.4.199_ref28","first-page":"531","volume":"40","author":"Itoh","year":"2013","journal-title":"Clin Exp Obstet Gynecol"},{"key":"10.6065\/apem.2016.21.4.199_ref29","doi-asserted-by":"crossref","first-page":"E1035","DOI":"10.1152\/ajpendo.00789.2007","volume":"294","author":"Toth","year":"2008","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.6065\/apem.2016.21.4.199_ref30","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1016\/j.fertnstert.2006.04.043","volume":"86","author":"Chu","year":"2006","journal-title":"Fertil Steril"}],"container-title":["Annals of Pediatric Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.6065\/apem.2016.21.4.199","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.6065\/apem.2016.21.4.199","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-apem.org\/upload\/pdf\/apem-21-199.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T10:49:18Z","timestamp":1564051758000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-apem.org\/journal\/view.php?doi=10.6065\/apem.2016.21.4.199"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.6065\/apem.2016.21.4.199","relation":{},"ISSN":["2287-1012","2287-1292"],"issn-type":[{"value":"2287-1012","type":"print"},{"value":"2287-1292","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.6065\/apem.2016.21.4.199","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.6065\/apem.2016.21.4.199","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"http:\/\/e-apem.org\/DOIx.php?id=10.6065\/apem.2016.21.4.199","URL":"http:\/\/e-apem.org\/DOIx.php?id=10.6065\/apem.2016.21.4.199","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2016-06-19","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-07-15","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-08-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-12-31","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2016 Annals of Pediatric Endocrinology & Metabolism","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}