{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:33:40Z","timestamp":1782927220993,"version":"3.54.5"},"reference-count":37,"publisher":"Korean Society of Pediatric Endocrinology","issue":"2","license":[{"start":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T00:00:00Z","timestamp":1636934400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Ministry of Health of Ukraine"},{"name":"I. Horbachevsky Ternopil National Medical University"}],"content-domain":{"domain":["e-apem.org"],"crossmark-restriction":true},"short-container-title":["Ann Pediatr Endocrinol Metab"],"published-print":{"date-parts":[[2022,6,30]]},"abstract":"<jats:p>Purpose: This work aims to determine the association between vitamin D deficiency and metabolic syndrome in overweight and obese adolescents from Ukraine.Methods: Anthropometric measurements were taken and general and biochemical examinations were performed on 136 obese and overweight adolescents and 60 adolescents with normal body weight. The vitamin D status was determined using 25-hydroxyvitamin D (25(OH)D) (calcidiol) levels in blood serum. To establish the factors influencing vitamin D status, the subjects were asked to answer a questionnaire and 2007 International Diabetes Federation diagnostic criteria were used to determine the incidence of metabolic syndrome. All research results were processed statistically.Results: A calcidiol sufficiency level was found in 3.9% of obese adolescents and 6.7% of overweight adolescents. Metabolic syndrome was found in 64.4% of obese adolescents with vitamin D deficiency, and in 26.2% of overweight adolescents. Factors associated with an increased risk of developing vitamin D deficiency in adolescents with metabolic syndrome included male sex (p=0.042), low income per family member (p=0.040), daily milk consumption of up to 1 cup per day (p=0.001), physical activity (p=0.001), duration of outdoor stays (p=0.001), and passive rest in front of a computer or television (p=0.001). Adolescents with metabolic syndrome were found predominance of body mass index (p&lt;0.001), waist circumference (p&lt;0.001), fasting blood glucose level (\u0420&lt;0.001), and decreased calcidiol level (p=0.022). Among metabolic syndrome components, vitamin D deficiency was strongly associated with waist circumference and increased fasting blood glucose (p&lt;0.05).Conclusion: Vitamin D deficiency is prevalent in overweight and obese adolescents from Ukraine. Vitamin D deficiency is associated with metabolic syndrome criteria in overweight and obese adolescents.<\/jats:p>","DOI":"10.6065\/apem.2142158.079","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T04:04:56Z","timestamp":1636949096000},"page":"113-120","update-policy":"https:\/\/doi.org\/10.6065\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The association between vitamin D deficiency and metabolic syndrome in Ukrainian adolescents with overweight and obesity"],"prefix":"10.6065","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7849-4560","authenticated-orcid":true,"given":"Anna-Mariia","family":"Shulhai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7271-6364","authenticated-orcid":true,"given":"Halyna","family":"Pavlyshyn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7052-8324","authenticated-orcid":true,"given":"Shulhai","family":"Oleksandra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6816-8614","authenticated-orcid":true,"given":"Victoria","family":"Furdela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4096","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-017-9424-1"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-0385"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.20996\/1819-6446-2016-12-2-227-233"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3390\/nu5010111"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2174\/138945011793591635"},{"key":"ref6","first-page":"3","volume-title":"","author":"Koundourakis","year":"2017"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1177\/1403494814541593"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.31688\/abmu.2019.54.1.08"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-018-1756-4"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/138.8.1482"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.5409\/wjcp.v6.i1.1"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.21037\/tp.2017.10.02"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1089\/met.2013.0127"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1089\/met.2012.0122"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00669"},{"key":"ref16","first-page":"1113","volume-title":"The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis","author":"Mottillo","year":"2010"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.18502\/ijph.v49i2.3106"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.21215\/kjfp.2016.6.4.315"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/580474"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.1038"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/109275"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.5603\/ep.2013.0012"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5448.2007.00271.x"},{"key":"ref24","volume-title":"Childhood overweight and obesity [Internet]","year":"c2021"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1017\/s1368980013003340"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.3390\/nu8110717"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.3164\/jcbn.12-81"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1530\/eje-11-0545"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.3390\/nu11102458"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.15407\/ubj93.02.072"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.4239\/wjd.v6.i7.896"},{"key":"ref32","first-page":"637","volume-title":"Waist circumference modifies the association between serum 25(OH)D and systolic blood pressure: results from NHANES 2001-2006","author":"Vogt","year":"2016"},{"key":"ref33","first-page":"54","volume-title":"Association between serum vitamin D and metabolic syndrome in middle-aged and older adults and role of supplementation therapy with vitamin D","author":"Verrusio","year":"2017"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-35229-2"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2014.00228"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1039\/d0fo03230a"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.3109\/09637486.2014.886186"}],"container-title":["Annals of Pediatric Endocrinology &amp; Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/e-apem.org\/upload\/pdf\/apem-2142158-079.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-apem.org\/journal\/view.php?doi=10.6065\/apem.2142158.079","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-apem.org\/upload\/pdf\/apem-2142158-079.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T23:15:54Z","timestamp":1656544554000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-apem.org\/journal\/view.php?doi=10.6065\/apem.2142158.079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,30]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,6]]}},"URL":"https:\/\/doi.org\/10.6065\/apem.2142158.079","relation":{},"ISSN":["2287-1012","2287-1292"],"issn-type":[{"value":"2287-1012","type":"print"},{"value":"2287-1292","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,30]]},"assertion":[{"value":"2021-08-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-15","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-30","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}