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Those who consume excessive iodine risk developing hypothyroidism and thyroid autoimmunity. A transient hyperthyroid condition may rapidly increase iodine consumption. Iodine deficiency is common across the globe, and provision of supplementary iodine, in forms such as iodized salt or vegetable oil, has many benefits. Vegetarians, for instance, may not consume adequate amounts of iodine in some countries with high iodine content. Reduced dietary iodine intakes may be a consequence of efforts to reduce salt intakes to prevent hypertension. In addition, iodine consumption is decreasing in many countries, even among those where endemic goiter has previously been eradicated, leading to the re-emergence of iodine-deficiency-related disorders such as goiter. This review will discuss how iodine can contribute to the development of thyroid disease.<\/jats:p>","DOI":"10.6065\/apem.2244186.093","type":"journal-article","created":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T03:46:48Z","timestamp":1672285608000},"page":"256-264","update-policy":"https:\/\/doi.org\/10.6065\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Impact of iodine intake on the pathogenesis of autoimmune thyroid disease in children and adults"],"prefix":"10.6065","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9368-3434","authenticated-orcid":true,"given":"Iyshwarya Bhaskar","family":"Kalarani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9307-5428","authenticated-orcid":true,"given":"Ramakrishnan","family":"Veerabathiran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4096","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-012-9703-2"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cegh.2022.101010"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1530\/eje-14-0047"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1017\/s0029665118001192"},{"key":"ref5","first-page":"8","volume-title":"Selenium and autoimmune thyroiditis","author":"Nacamulli","year":"2013"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1012985"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2016.0635"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.18203\/2349-2902.isj20191056"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.2298\/sarh160122093m"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.apgeochem.2015.09.013"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.116.139725"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1017\/s1368980016000951"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3390\/nu10010100"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.29219\/fnr.v62.1291. 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