{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T19:48:09Z","timestamp":1783367289840,"version":"3.54.6"},"reference-count":61,"publisher":"XMLink","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["J Menopausal Med"],"published-print":{"date-parts":[[2015]]},"DOI":"10.6118\/jmm.2015.21.1.1","type":"journal-article","created":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T10:41:53Z","timestamp":1430217713000},"page":"1","update-policy":"https:\/\/doi.org\/10.6118\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["New Antiresorptive Therapies for Postmenopausal Osteoporosis"],"prefix":"10.6118","volume":"21","author":[{"given":"Hee-Jeong","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Family Medicine, Eulji University School of Medicine, Daejeon, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.6118\/jmm.2015.21.1.1_ref1","unstructured":"Food and Drug Administration. FDA approves new injectable osteoporosis treatment for postmenopausal women. Silver Spring, MD: Food and Drug Administration. 2010. cited by 2015 Mar 19. Available from: http:\/\/www.fda.gov\/NewsEvents\/Newsroom\/PressAnnouncements\/ucm214150.htm"},{"key":"10.6118\/jmm.2015.21.1.1_ref2","unstructured":"European Medicines Agency. Prolia (denosumab). London, UK. Euopean Medicines Agency. 2015. cited by 2015 Mar 19. Available from: http:\/\/www.ema.europa.eu\/ema\/index.jsp?curl=pages\/medicines\/human\/medicines\/001120\/human_med_001324.jsp&mid=WC0b01ac058001d124"},{"key":"10.6118\/jmm.2015.21.1.1_ref3","unstructured":"Amgen Inc. Prolia\u00ae (denosumab). Thousand Oaks, CA. Amgen Inc. 2010. cited by 2015 Feb 16. Available from: http:\/\/pi.amgen.com\/united_states\/prolia\/prolia_pi.pdf"},{"key":"10.6118\/jmm.2015.21.1.1_ref4","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1056\/NEJMoa0809493","volume":"361","author":"Cummings","year":"2009","journal-title":"N Engl J Med"},{"key":"10.6118\/jmm.2015.21.1.1_ref5","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/16852","volume":"397","author":"Kong","year":"1999","journal-title":"Nature"},{"key":"10.6118\/jmm.2015.21.1.1_ref6","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1359\/JBMR.040305","volume":"19","author":"Bekker","year":"2004","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref7","doi-asserted-by":"crossref","first-page":"2645","DOI":"10.1002\/jps.20178","volume":"93","author":"Lobo","year":"2004","journal-title":"J Pharm Sci"},{"key":"10.6118\/jmm.2015.21.1.1_ref8","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1210\/jc.2010-2784","volume":"96","author":"Boonen","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"10.6118\/jmm.2015.21.1.1_ref9","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1002\/jbmr.1479","volume":"27","author":"Papapoulos","year":"2012","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref10","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1002\/jbmr.536","volume":"27","author":"McClung","year":"2012","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref11","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1359\/jbmr.0809010","volume":"24","author":"Brown","year":"2009","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref12","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1359\/jbmr.090716","volume":"25","author":"Kendler","year":"2010","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref13","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1002\/jbmr.1613","volume":"27","author":"Block","year":"2012","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref14","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1210\/jc.2010-1502","volume":"96","author":"Bone","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"10.6118\/jmm.2015.21.1.1_ref15","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1002\/jbmr.448","volume":"26","author":"Brown","year":"2011","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref16","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1007\/s00198-010-1378-z","volume":"22","author":"Kendler","year":"2011","journal-title":"Osteoporos Int"},{"key":"10.6118\/jmm.2015.21.1.1_ref17","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s00198-011-1755-2","volume":"23","author":"Watts","year":"2012","journal-title":"Osteoporos Int"},{"key":"10.6118\/jmm.2015.21.1.1_ref18","first-page":"614","volume":"33","author":"Mart\u00edn-Baez","year":"2013","journal-title":"Nefrologia"},{"key":"10.6118\/jmm.2015.21.1.1_ref19","doi-asserted-by":"crossref","first-page":"242","DOI":"10.5694\/mja13.10038","volume":"199","author":"McLachlan","year":"2013","journal-title":"Med J Aust"},{"key":"10.6118\/jmm.2015.21.1.1_ref20","doi-asserted-by":"crossref","first-page":"756 e1","DOI":"10.1016\/j.ajem.2012.11.011","volume":"31","author":"Ungprasert","year":"2013","journal-title":"Am J Emerg Med"},{"key":"10.6118\/jmm.2015.21.1.1_ref21","doi-asserted-by":"crossref","first-page":"5132","DOI":"10.1200\/JCO.2010.29.7101","volume":"28","author":"Stopeck","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.6118\/jmm.2015.21.1.1_ref22","unstructured":"Medicines and Healthcare Products Regulatory Agency. Denosumab 60 mg (prolia\u25be). London, UK. Medicines and Healthcare Products Regulatory Agency. 2013. cited by 2015 Feb 17. Available from: https:\/\/www.gov.uk\/drug-safety-update\/denosumab-60-mg-prolia"},{"key":"10.6118\/jmm.2015.21.1.1_ref23","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1101\/gad.12.9.1260","volume":"12","author":"Bucay","year":"1998","journal-title":"Genes Dev"},{"key":"10.6118\/jmm.2015.21.1.1_ref24","doi-asserted-by":"crossref","first-page":"473","DOI":"10.2353\/ajpath.2009.080957","volume":"175","author":"Helas","year":"2009","journal-title":"Am J Pathol"},{"key":"10.6118\/jmm.2015.21.1.1_ref25","doi-asserted-by":"crossref","first-page":"149","DOI":"10.20452\/pamw.1678","volume":"123","author":"Janda","year":"2013","journal-title":"Pol Arch Med Wewn"},{"key":"10.6118\/jmm.2015.21.1.1_ref26","doi-asserted-by":"crossref","first-page":"182060","DOI":"10.1155\/2013\/182060","volume":"2013","author":"Augoulea","year":"2013","journal-title":"Int J Endocrinol"},{"key":"10.6118\/jmm.2015.21.1.1_ref27","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1136\/heartjnl-2012-302240","volume":"99","author":"Mogelvang","year":"2013","journal-title":"Heart"},{"key":"10.6118\/jmm.2015.21.1.1_ref28","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1161\/01.CIR.0000127957.43874.BB","volume":"109","author":"Kiechl","year":"2004","journal-title":"Circulation"},{"key":"10.6118\/jmm.2015.21.1.1_ref29","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1002\/jbmr.149","volume":"25","author":"Reid","year":"2010","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref30","first-page":"302","volume":"37","author":"Silva","year":"2012","journal-title":"Acta Reumatol Port"},{"key":"10.6118\/jmm.2015.21.1.1_ref31","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1001\/jama.2010.1500","volume":"304","author":"Chlebowski","year":"2010","journal-title":"JAMA"},{"key":"10.6118\/jmm.2015.21.1.1_ref32","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/S1470-2045(12)70075-X","volume":"13","author":"Anderson","year":"2012","journal-title":"Lancet Oncol"},{"key":"10.6118\/jmm.2015.21.1.1_ref33","doi-asserted-by":"crossref","first-page":"3999","DOI":"10.1210\/en.2005-0030","volume":"146","author":"Komm","year":"2005","journal-title":"Endocrinology"},{"key":"10.6118\/jmm.2015.21.1.1_ref34","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.mce.2008.01.027","volume":"287","author":"Crabtree","year":"2008","journal-title":"Mol Cell Endocrinol"},{"key":"10.6118\/jmm.2015.21.1.1_ref35","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1210\/en.2008-1210","volume":"150","author":"Peano","year":"2009","journal-title":"Endocrinology"},{"key":"10.6118\/jmm.2015.21.1.1_ref36","doi-asserted-by":"crossref","first-page":"S88","DOI":"10.1016\/j.fertnstert.2006.07.236","volume":"86","author":"Van Duren","year":"2006","journal-title":"Fertil Steril"},{"key":"10.6118\/jmm.2015.21.1.1_ref37","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1097\/GME.0b013e318271f5e7","volume":"20","author":"Harvey","year":"2013","journal-title":"Menopause"},{"key":"10.6118\/jmm.2015.21.1.1_ref38","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1097\/AOG.0b013e31828c5974","volume":"121","author":"Pinkerton","year":"2013","journal-title":"Obstet Gynecol"},{"key":"10.6118\/jmm.2015.21.1.1_ref39","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.fertnstert.2009.02.093","volume":"92","author":"Lindsay","year":"2009","journal-title":"Fertil Steril"},{"key":"10.6118\/jmm.2015.21.1.1_ref40","doi-asserted-by":"crossref","first-page":"E189","DOI":"10.1210\/jc.2013-1707","volume":"99","author":"Pinkerton","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"10.6118\/jmm.2015.21.1.1_ref41","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.fertnstert.2009.03.113","volume":"92","author":"Lobo","year":"2009","journal-title":"Fertil Steril"},{"key":"10.6118\/jmm.2015.21.1.1_ref42","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1097\/gme.0b013e3181a7df0d","volume":"16","author":"Pinkerton","year":"2009","journal-title":"Menopause"},{"key":"10.6118\/jmm.2015.21.1.1_ref43","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/gme.0b013e3181b7c65f","volume":"17","author":"Kagan","year":"2010","journal-title":"Menopause"},{"key":"10.6118\/jmm.2015.21.1.1_ref44","doi-asserted-by":"crossref","first-page":"132","DOI":"10.3109\/13697130903305627","volume":"13","author":"Bachmann","year":"2010","journal-title":"Climacteric"},{"key":"10.6118\/jmm.2015.21.1.1_ref45","first-page":"SAT-31","volume-title":"Low risk of thrombophilia with bazedoxifene\/conjugated estrogens: summary of pooled coagulation data from the selective estrogens, menopause, and response to therapy trialsThe Endocrine Society's 94th Annual Meeting and Expo","author":"Skouby","year":"2012"},{"key":"10.6118\/jmm.2015.21.1.1_ref46","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/j.fertnstert.2009.05.093","volume":"92","author":"Archer","year":"2009","journal-title":"Fertil Steril"},{"key":"10.6118\/jmm.2015.21.1.1_ref47","unstructured":"Pfizer Inc. DUAVEE\u00ae (conjugated estrogens\/bazedoxifene) tablets for oral use. Philadelphia, PA. Pfizer Inc. 2013. cited by 2015 Feb 17. Available from: http:\/\/labeling.pfizer.com\/ShowLabeling.aspx?id=1174"},{"key":"10.6118\/jmm.2015.21.1.1_ref48","doi-asserted-by":"crossref","first-page":"235","DOI":"10.2147\/CIA.S26729","volume":"7","author":"Ng","year":"2012","journal-title":"Clin Interv Aging"},{"key":"10.6118\/jmm.2015.21.1.1_ref49","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1359\/JBMR.040603","volume":"19","author":"V\u00e4\u00e4r\u00e4niemi","year":"2004","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref50","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1515\/BC.1999.084","volume":"380","author":"Xia","year":"1999","journal-title":"Biol Chem"},{"key":"10.6118\/jmm.2015.21.1.1_ref51","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0039-128X(00)00097-0","volume":"65","author":"Furuyama","year":"2000","journal-title":"Steroids"},{"key":"10.6118\/jmm.2015.21.1.1_ref52","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1196\/annals.1346.018","volume":"1068","author":"Troen","year":"2006","journal-title":"Ann N Y Acad Sci"},{"key":"10.6118\/jmm.2015.21.1.1_ref53","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1002\/cbic.200600149","volume":"7","author":"Black","year":"2006","journal-title":"Chembiochem"},{"key":"10.6118\/jmm.2015.21.1.1_ref54","doi-asserted-by":"crossref","first-page":"355","DOI":"10.2174\/156802606776287036","volume":"6","author":"Kim","year":"2006","journal-title":"Curr Top Med Chem"},{"key":"10.6118\/jmm.2015.21.1.1_ref55","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.bmcl.2007.12.047","volume":"18","author":"Gauthier","year":"2008","journal-title":"Bioorg Med Chem Lett"},{"key":"10.6118\/jmm.2015.21.1.1_ref56","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1359\/jbmr.091035","volume":"25","author":"Bone","year":"2010","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref57","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1002\/jbmr.1695","volume":"27","author":"Langdahl","year":"2012","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref58","unstructured":"Merck. Merck announces data from pivotal phase 3 fracture outcomes study for odanacatib, an investigational oral, once-weekly treatment for osteoporosis. Kenilworth, NJ. Merck & Co., Inc. 2014. cited by 2015 Feb 17. Available from: http:\/\/www.mercknewsroom.com\/news-release\/research-and-development-news\/merck-announces-data-pivotal-phase-3-fracture-outcomes-st"},{"key":"10.6118\/jmm.2015.21.1.1_ref59","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1002\/jbmr.1541","volume":"27","author":"Khosla","year":"2012","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref60","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1002\/jbmr.1475","volume":"27","author":"Masarachia","year":"2012","journal-title":"J Bone Miner Res"},{"key":"10.6118\/jmm.2015.21.1.1_ref61","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1002\/jbmr.5650071216","volume":"7","author":"Balena","year":"1992","journal-title":"J Bone Miner Res"}],"container-title":["Journal of Menopausal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.6118\/jmm.2015.21.1.1","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.6118\/jmm.2015.21.1.1","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/e-jmm.org\/DOIx.php?id=10.6118\/jmm.2015.21.1.1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T16:35:44Z","timestamp":1748363744000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-jmm.org\/DOIx.php?id=10.6118\/jmm.2015.21.1.1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":61,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.6118\/jmm.2015.21.1.1","relation":{},"ISSN":["2288-6478","2288-6761"],"issn-type":[{"value":"2288-6478","type":"print"},{"value":"2288-6761","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.6118\/jmm.2015.21.1.1","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.6118\/jmm.2015.21.1.1","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"https:\/\/e-jmm.org\/DOIx.php?id=10.6118\/jmm.2015.21.1.1","URL":"https:\/\/e-jmm.org\/DOIx.php?id=10.6118\/jmm.2015.21.1.1","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2015-02-22","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-03-19","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-03-25","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-04-27","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2015 by The Korean Society of Menopause","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/).","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}