{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T18:37:19Z","timestamp":1787683039980,"version":"build-2784847793"},"reference-count":19,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dan Med J"],"abstract":"<jats:p>INTRODUCTION. Blunt cerebrovascular injuries (BCVI) associated with cervical spine injuries (CSI) carry a high risk of morbidity and mortality. This nationwide Danish study, covering the years 2017-2023, aimed to identify key BCVI predictors in patients with CSI to support improved early detection and management strategies.\n\nMETHODS. The study analysed data from four level-1 trauma centres using the Abbreviated Injury Scale to classify BCVI cases. Factors assessed included age, sex, type of cervical injury and the Injury Severity Score (ISS).\n\nRESULTS. Age and sex were not significant predictors of BCVI (p = 0.12, p = 0.65). However, any form of CSI was a strong predictor (p &lt; 0.001; odds ratios (OR) = 26.3; confidence intervals (95% CI): 16.84-41.12), as were cervical spine ligamentous injuries (p = 0.0007; OR = 5.4; 95% CI: 2.3-12.89). An increase in ISS score significantly correlated with BCVI risk (p = 0.001; OR = 1.03 per unit increase; 95% CI: 1.01-1.05). Specific cervical fractures were not independent predictors of BCVI.\n\nCONCLUSIONS. From a Danish cohort of patients admitted to a level 1 trauma centre, we found a BCVI incidence of three per thousand. In case of verified injury to the cervical region, the incidence rose to 6.25%. Our findings underscore the need for increased vigilance and a standardised nationwide algorithm to prevent disability, loss of health-related quality of life, and mortality in CSI patients at risk of BCVI.\n\nFUNDING. The study was funded by Offerfonden, Dagmar Marshall Fonden, and Torben &amp; Alice Frimodt Fonden.\n\nTRIAL REGISTRATION. The data collection was approved by the local ethical committee and the Central Denmark Region Office for Research: 1-45-70-19-23.<\/jats:p>","DOI":"10.61409\/a01240067","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T06:09:45Z","timestamp":1738649385000},"page":"1-8","source":"Crossref","is-referenced-by-count":1,"title":["Blunt cerebrovascular injuries and association with cervical spine injury"],"prefix":"10.61409","author":[{"given":"Hanna Sissel Foldager","family":"Jeppesen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lasse","family":"Kristensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"Brink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian","family":"H\u00f8y","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"40208","published-online":{"date-parts":[[2025,1,1]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Sethi RK, Kozin ED, Fagenholz PJ et al. 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