{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T12:13:31Z","timestamp":1788783211054,"version":"build-2803163510"},"reference-count":0,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dan Med J"],"abstract":"<jats:p>INTRODUCTION. Previous Danish data (1980-2014) showed a significant increase in thyroid cancer incidence among children and adolescents. This study examined whether this trend persisted during the most recent decade.\n\nMETHODS. All patients aged 0-24 years diagnosed with thyroid cancer in Denmark between 2015 and 2024 were identified in the Danish Cancer Registry. Crude and age-specific incidence rates (IRs) per 100,000 were calculated for children\/adolescents (0-17 years) and young adults (18-24 years), stratified by sex and histological subtype. Trends were analysed using Joinpoint regression.\n\nRESULTS. A total of 159 cases were identified; 81% were female. Median age at diagnosis was 16 years in the 0-17-year group and 22 years in the 18-24-year group. Papillary carcinoma was the most common subtype in both groups (68% and 82%). From 2015 to 2024, overall IRs increased non-significantly from 0.65 to 0.94 per 100,000. Across 1980-2024, the incidence increased significantly in young adults (average annual percentage change (AAPC) = 3.4%) and in the total population (AAPC = 2.8%), but not in children\/adolescents. IRs increased with age, reaching 4.89 among 24-year-old females and 1.01 among males.\n\nCONCLUSIONS. The incidence of thyroid carcinoma in Danish children and young adults has remained stable during the 2015-2024 period, with persistent female predominance and papillary carcinoma as the dominant subtype. Long-term trends continue to show an increasing incidence overall, mainly driven by an increasing incidence among young adults.\n\nFUNDING. None.\n\nTRIAL REGISTRATION. Not relevant.<\/jats:p>","DOI":"10.61409\/a01260063","type":"journal-article","created":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T12:06:23Z","timestamp":1788782783000},"page":"1-5","source":"Crossref","is-referenced-by-count":0,"title":["The incidence of thyroid cancer in Danish children, adolescents and young adults"],"prefix":"10.61409","author":[{"given":"Ulrik \u00d8rs\u00f8","family":"Andersen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob Myllerup","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Gr\u00f8nh\u00f8j","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Hjuler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"40208","published-online":{"date-parts":[[2026,8]]},"container-title":["Danish Medical Journal"],"original-title":[],"deposited":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T12:06:26Z","timestamp":1788782786000},"score":1,"resource":{"primary":{"URL":"https:\/\/ugeskriftet.dk\/dmj\/A01260063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":0,"URL":"https:\/\/doi.org\/10.61409\/a01260063","relation":{},"ISSN":["2245-1919"],"issn-type":[{"value":"2245-1919","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]}}}