{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T14:58:08Z","timestamp":1765378688395,"version":"3.46.0"},"reference-count":9,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dan Med J"],"abstract":"<jats:p>INTRODUCTION. This report presents a single-institution prospective case series evaluating the feasibility and effect of outpatient local anaesthesia radiofrequency ablation-assisted soft palate volumetric tissue reduction (RFA-SP) and turbinoplasty (RFA-T) for treatment of patients with obstructive sleep apnoea (OSA) and\/or snoring.\n\nMETHODS. A total of 72 patients with Apnea-Hypopnoea Index (AHI) &gt; 5 and\/or subjective snoring treated in 2024 were evaluated after surgery, including cardiorespiratory monitoring (CRM) and patient questionnaire evaluation. Main endpoints were AHI, Snore Index (SI), Epworth Sleepiness Scale and scored impact of sleep-disordered breathing on quality of life.\n\nRESULTS. We conclude that the procedures have low morbidity and high patient satisfaction. Approximately one in two patients had improved symptoms. However, improvement in AHI and SI was mainly seen in total or non-supine positions. The main limitations of our study are: the placebo effect in patient self-evaluations, the relatively small study population, the availability of comprehensive and recent pre- and post-surgery CRMs and the underlying premise that the mechanisms of sleep-disordered breathing remain poorly understood.\n\nCONCLUSIONS. Outpatient RFA-SP and RFA-T under local anaesthesia effectively improve symptoms and quality of life in patients with OSA and snoring, producing complete resolution in selected cases. The best outcomes are seen in non-supine OSA, highlighting the need for careful preoperative assessment to optimise patient selection.\n\nFUNDING. None.\n\nTRIAL REGISTRATION. The study protocol was approved by the Aarhus University Hospital Management. The Central Denmark Region Committees on Health Research Ethics were consulted and found the project non-notifiable.<\/jats:p>","DOI":"10.61409\/a06250516","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T09:54:31Z","timestamp":1764237271000},"page":"1-7","source":"Crossref","is-referenced-by-count":0,"title":["Local-anaesthesia, one-step sleep surgery"],"prefix":"10.61409","author":[{"given":"Jens","family":"Krarup","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesper","family":"Bille","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milos","family":"Fuglsang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"40208","published-online":{"date-parts":[[2025,11]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Rotenberg BW, Murariu D, Pang KP. Trends in CPAP adherence over twenty years of data collection: a flattened curve. J Otolaryngol Head Neck Surg. 2016;45(1):43. https:\/\/doi.org\/10.1186\/s40463-016-0156-0","DOI":"10.1186\/s40463-016-0156-0"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Hyt\u00f6nen ML, B\u00e4ck LJJ, Malmivaara AV, et al. Radiofrequency thermal ablation for patients with nasal symptoms: a systematic review of effectiveness and complications. Eur Arch Otorhinolaryngol. 2009;266(8):1257-1266. https:\/\/doi.org\/10.1007\/s00405-009-0914-y","DOI":"10.1007\/s00405-009-0914-y"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"B\u00e4ck LJJ, Hyt\u00f6nen ML, Roine RP, et al. Radiofrequency ablation treatment of soft palate for patients with snoring: a systematic review of effectiveness and adverse effects. Laryngoscope. 2009;119(6):1241-1250. https:\/\/doi.org\/10.1002\/lary.20215","DOI":"10.1002\/lary.20215"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Pang KP, Siow JK. Sutter bipolar radiofrequency volumetric tissue reduction of palate for snoring and mild obstructive sleep apnoea: is one treatment adequate? J Laryngol Otol. 2009;123(7):750-754. https:\/\/doi.org\/10.1017\/S0022215109004253","DOI":"10.1017\/S0022215109004253"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Karakurt SE, \u00c7etin MA, Apayd\u0131n E, et al. Does inferior turbinate outfracture provide additional benefit when combined with inferior turbinate radiofrequency ablation? Eur Arch Otorhinolaryngol. 2021;278(8):2869-2874. https:\/\/doi.org\/10.1007\/s00405-020-06556-w","DOI":"10.1007\/s00405-020-06556-w"},{"key":"ref5","unstructured":"Fuglsang M, Lilja-Fischer JK, Petersen KB, et al. Subjective tiredness does not correlate with the Apnoea-Hypopnoea Index. Dan Med J. 2019;66(5):A5545"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Patel S, Kon SSC, Nolan CM, et al. The Epworth Sleepiness Scale: minimum clinically important difference in obstructive sleep apnea. Am J Respir Crit Care Med. 2018;197(7):961-963. https:\/\/doi.org\/10.1164\/rccm.201704-0672LE","DOI":"10.1164\/rccm.201704-0672LE"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Magalang UJ, Johns JN, Wood KA, et al. Home sleep apnea testing: comparison of manual and automated scoring across international sleep centers. Sleep Breath. 2019;23(1):25-31. https:\/\/doi.org\/10.1007\/s11325-018-1715-6","DOI":"10.1007\/s11325-018-1715-6"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Fattal D, Hester S, Wendt L. Body weight and obstructive sleep apnea: a mathematical relationship between body mass index and apnea-hypopnea index in veterans. J Clin Sleep Med. 2022;18(12):2723-2729. https:\/\/doi.org\/10.5664\/jcsm.10190","DOI":"10.5664\/jcsm.10190"}],"container-title":["Danish Medical Journal"],"original-title":[],"deposited":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T14:53:13Z","timestamp":1765378393000},"score":1,"resource":{"primary":{"URL":"https:\/\/ugeskriftet.dk\/dmj\/A06250516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":9,"URL":"https:\/\/doi.org\/10.61409\/a06250516","relation":{},"ISSN":["2245-1919"],"issn-type":[{"type":"electronic","value":"2245-1919"}],"subject":[],"published":{"date-parts":[[2025,11]]}}}