{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T00:08:32Z","timestamp":1758931712700,"version":"3.44.0"},"reference-count":20,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dan Med J"],"abstract":"<jats:p>INTRODUCTION. In recent years, outpatient surgical treatment for ankle fractures has been introduced for selected fracture types and patients with a low degree of comorbidity. Limited evidence is available to guide the choice between inpatient and outpatient care for ankle fractures. This randomised controlled trial aims to investigate the effect of inpatient versus outpatient surgery of ankle fractures on patient-reported outcomes at 12 weeks.\n\nMETHODS. This study is a single-centre non-inferiority randomised controlled trial investigating outpatient care for surgically treated ankle fractures. A total of 86 patients will be included in the study and randomised 1:1 to either outpatient or inpatient care. The primary outcome is the Foot and Ankle Outcome Score at three months after surgery. Secondary outcomes will include patient satisfaction, pain, physical function and adverse events.\n\nCONCLUSIONS. Conducting a randomised controlled trial investigating inpatient versus outpatient surgery for ankle fractures on both patient-reported outcomes, patient satisfaction, adverse events, pain, function and bone healing will provide evidence to guide future recommendations in the planning of surgical treatment for ankle fractures.\n\nFUNDING. The study is partially funded by Helsefonden and the North Denmark Region.\n\nTRIAL REGISTRATION. The study was pre-registered on Clinicaltrials.gov ID: NCT05389436, 20 May 2022.<\/jats:p>","DOI":"10.61409\/a10240746","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T02:35:07Z","timestamp":1751423707000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["Outpatient versus inpatient surgery for ankle fractures \u2013 a protocol for a randomised controlled trial"],"prefix":"10.61409","author":[{"given":"Christian G.R.","family":"Rasmussen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Larsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Pedersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rasmus","family":"Elsoe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"40208","published-online":{"date-parts":[[2025,6]]},"reference":[{"doi-asserted-by":"publisher","unstructured":"Elsoe R, Ostgaard SE, Larsen P. Population-based epidemiology of 9767 ankle fractures. Foot Ankle Surg. 2018;24(1):34-39. https:\/\/doi.org\/10.1016\/j.fas.2016.11.002","key":"ref0","DOI":"10.1016\/j.fas.2016.11.002"},{"doi-asserted-by":"publisher","unstructured":"Goost H, Wimmer MD, Barg A, et al. Fractures of the ankle joint: investigation and treatment options. Dtsch Arztebl Int. 2014;111(21):377-388. https:\/\/doi.org\/10.3238\/arztebl.2014.0377","key":"ref1","DOI":"10.3238\/arztebl.2014.0377"},{"unstructured":"Court-Brown CM, Heckman JD, McQueen MM, et al., eds. Rockwood and Green's fractures in adults. 8th ed. Walters Kluwer, 2015","key":"ref2"},{"doi-asserted-by":"publisher","unstructured":"Court-Brown CM, McBirnie J, Wilson G. Adult ankle fractures - an increasing problem? Acta Orthop Scand. 1998;69(1):43-47. https:\/\/doi.org\/10.3109\/17453679809002355","key":"ref3","DOI":"10.3109\/17453679809002355"},{"doi-asserted-by":"publisher","unstructured":"Bengn\u00e9r U, Johnell O, Redlund-Johnell I. Epidemiology of ankle fracture 1950 and 1980: increasing incidence in elderly women. Acta Orthop Scand. 1986;57(1):35-37. https:\/\/doi.org\/10.3109\/17453678608993211","key":"ref4","DOI":"10.3109\/17453678608993211"},{"unstructured":"Tengberg PT, Ban I. Treatment of ankle fractures. Ugeskr Laeger. 2018;180:V11170883","key":"ref5"},{"doi-asserted-by":"publisher","unstructured":"Larsen P, Al-Bayati M, Els\u00f8e R. The Foot and Ankle Outcome Score (FAOS) during early recovery after ankle fracture. Foot Ankle Int. 2021;42(9):1179-1184. https:\/\/doi.org\/10.1177\/10711007211002811","key":"ref6","DOI":"10.1177\/10711007211002811"},{"doi-asserted-by":"publisher","unstructured":"Weckbach S, Flierl MA, Huber-Lang M, et al. Surgical treatment of ankle fractures as an outpatient procedure. A safe and resource-efficient concept? Unfallchirurg. 2011;114(10):938-942. https:\/\/doi.org\/10.1007\/s00113-011-2066-y","key":"ref7","DOI":"10.1007\/s00113-011-2066-y"},{"doi-asserted-by":"publisher","unstructured":"Murray AM, McDonald SE, Archbold P, Crealey GE. Cost description of inpatient treatment for ankle fracture. Injury. 2011;42(11):1226-1229. https:\/\/doi.org\/10.1016\/j.injury.2010.08.023","key":"ref8","DOI":"10.1016\/j.injury.2010.08.023"},{"doi-asserted-by":"publisher","unstructured":"Lloyd JM, Martin R, Rajagopalan S, et al. An innovative and cost-effective way of managing ankle fractures prior to surgery - home therapy. Ann R Coll Surg Engl. 2010;92(7):615-618. https:\/\/doi.org\/10.1308\/003588410X12699663904358","key":"ref9","DOI":"10.1308\/003588410X12699663904358"},{"doi-asserted-by":"publisher","unstructured":"Malik AT, Quatman CE, Khan SN, et al. Outpatient versus inpatient surgical fixation of isolated ankle fractures: an analysis of 90-day complications, readmissions, and costs. J Foot Ankle Surg. 2020;59(3):502-506. https:\/\/doi.org\/10.1053\/j.jfas.2019.09.030","key":"ref10","DOI":"10.1053\/j.jfas.2019.09.030"},{"doi-asserted-by":"publisher","unstructured":"Qin C, Dekker RG, Blough JT, Kadakia AR. Safety and outcomes of inpatient compared with outpatient surgical procedures for ankle fractures. J Bone Joint Surg Am. 2016;98(20):1699-1705. https:\/\/doi.org\/10.2106\/JBJS.15.01465","key":"ref11","DOI":"10.2106\/JBJS.15.01465"},{"doi-asserted-by":"publisher","unstructured":"Qin C, Dekker 2nd RG, Helfrich MM, Kadakia AR. Outpatient management of ankle fractures. Orthop Clin North Am. 2018;49(1):103-108. https:\/\/doi.org\/10.1016\/j.ocl.2017.08.012","key":"ref12","DOI":"10.1016\/j.ocl.2017.08.012"},{"doi-asserted-by":"publisher","unstructured":"Piaggio G, Elbourne DR, Pocock SJ, et al. Reporting of noninferiority and equivalence randomized trials: extension of the CONSORT 2010 statement. JAMA. 2012;308(24):2594-2604. https:\/\/doi.org\/10.1001\/jama.2012.87802","key":"ref13","DOI":"10.1001\/jama.2012.87802"},{"unstructured":"FAOS. A user's guide to: Foot and Ankle Outcome Score FAOS. www.koos.nu\/FAOSGuide2003_RC.pdf (14 Dec 2022)","key":"ref14"},{"doi-asserted-by":"publisher","unstructured":"Thong ISK, Jensen MP, Mir\u00f3 J, Tan G. The validity of pain intensity measures: what do the NRS, VAS, VRS, and FPS-R measure? Scand J Pain. 2018;18(1):99-107. https:\/\/doi.org\/10.1515\/sjpain-2018-0012","key":"ref15","DOI":"10.1515\/sjpain-2018-0012"},{"doi-asserted-by":"publisher","unstructured":"Marcano-Fern\u00e1ndez F, Prada C, Johal H. Physical outcome measures: the role of strength and range of motion in orthopaedic research. Injury. 2020;51(suppl 2):S106-S110. https:\/\/doi.org\/10.1016\/j.injury.2019.11.017","key":"ref16","DOI":"10.1016\/j.injury.2019.11.017"},{"doi-asserted-by":"publisher","unstructured":"Shih CA, Jou IM, Lee PY, et al. Treating AO\/OTA 44B lateral malleolar fracture in patients over 50\u2009years of age: periarticular locking plate versus non-locking plate. J Orthop Surg Res. 2020;15(1):112. https:\/\/doi.org\/10.1186\/s13018-020-01622-9","key":"ref17","DOI":"10.1186\/s13018-020-01622-9"},{"unstructured":"EuroQol. EQ-5D-5L. https:\/\/euroqol.org\/eq-5d-instruments\/eq-5d-5l (14 Dec 2022)","key":"ref18"},{"doi-asserted-by":"publisher","unstructured":"Tegner Y, Lysholm J. Rating systems in the evaluation of knee ligament injuries. Clin Orthop Relat Res. 1985;(198):43-49","key":"ref19","DOI":"10.1097\/00003086-198509000-00007"}],"container-title":["Danish Medical Journal"],"original-title":[],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T12:58:28Z","timestamp":1758891508000},"score":1,"resource":{"primary":{"URL":"https:\/\/ugeskriftet.dk\/dmj\/A10240746"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":20,"URL":"https:\/\/doi.org\/10.61409\/a10240746","relation":{},"ISSN":["2245-1919"],"issn-type":[{"type":"electronic","value":"2245-1919"}],"subject":[],"published":{"date-parts":[[2025,6]]}}}