{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T13:35:59Z","timestamp":1782912959700,"version":"3.54.5"},"reference-count":13,"publisher":"Danish Medical Association","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dan Med J"],"abstract":"<jats:p>INTRODUCTION. Healthcare databases are a valuable source for epidemiological research in obstructive sleep apnoea, but accurately registered diagnoses are pivotal in contributing quality evidence. We examined positive predictive values (PPV) of the International Classification of Diseases, tenth version (ICD-10) diagnosis for \u201cobstructive sleep apnoea\u201d and \u201csleep apnoea\u201d in the Danish National Patient Register.  METHODS. Using the Danish National Patient Registry, we randomly sampled 100 patients from the North Denmark Region diagnosed with \u201cobstructive sleep apnoea\u201d (ICD-10 code DG4732) and 100 patients diagnosed with \u201csleep apnoea\u201d (DG473*) during the year 2020. We calculated the PPV using a documented Apnea-Hypopnea Index (AHI) \u2265 5 to confirm the recorded diagnosis. A total of 70 patients were referred to the private sector for assessment of the AHI and excluded due to limited access to their data.  RESULTS. The study population included 130 patients, among whom 64 were diagnosed with \u201cobstructive sleep apnoea\u201d, and 66 patients were registered with \u201csleep apnoea\u201d. The PPV for \u201cobstructive sleep apnoea\u201d was 93.8% (95% confidence interval (CI): 85.0-97.5%), and the PPV for \u201csleep apnoea\u201d was 80.3% (95% CI: 69.2-88.1%).  CONCLUSIONS. Our findings indicated a high validity of the ICD-10 code DG4732 with a PPV of 93.8% and a lower PPV (80.3%) for the ICD-10 code DG473* for identifying patients with obstructive sleep. The \u201cobstructive sleep apnoea\u201d diagnosis is a suitable source of data for epidemiological research to identify patients with the disease.  FUNDING. None.  TRIAL REGISTRATION. Not relevant.<\/jats:p>","DOI":"10.61409\/a11230701","type":"journal-article","created":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T06:56:58Z","timestamp":1716965818000},"page":"1-9","source":"Crossref","is-referenced-by-count":4,"title":["Validity of obstructive sleep apnoea diagnoses"],"prefix":"10.61409","volume":"71","author":[{"given":"Emilia Colding","family":"Ofverlind","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesper","family":"Bille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thure Filskov","family":"Overvad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Br\u00f8nnum","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ida Ehlers","family":"Albertsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"40208","published-online":{"date-parts":[[2024,6,1]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Punjabi NM. The epidemiology of adult obstructive sleep apnea. Proc Am Thorac Soc. 2008;5(2):136-43. doi: 10.1513\/pats.200709-155MG.","DOI":"10.1513\/pats.200709-155MG"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea. Am J Respir Crit Care Med. 2002;165(9):1217-39. doi: 10.1164\/rccm.2109080.","DOI":"10.1164\/rccm.2109080"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Gunta SP, Jakulla RS, Ubaid A et al. Obstructive sleep apnea and cardiovascular diseases: sad realities and untold truths regarding care of patients in 2022. Cardiovasc Ther. 2022;2022:6006127. doi: 10.1155\/2022\/6006127.","DOI":"10.1155\/2022\/6006127"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Udholm N, Fuglsang M, Lundbye-Christensen S et al. Obstructive sleep apnea and risk of suicide and self-harm: a Danish nationwide cohort study. Sleep. 2022;45(2):zsab286. doi: 10.1093\/sleep\/zsab286.","DOI":"10.1093\/sleep\/zsab286"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Jennum P, Baandrup L, T\u00f8nnesen P et al. Mortality and use of psychotropic medication in sleep apnoea patients: a population-wide register-based study. Sleep Med. 2018;43:19-24. doi: 10.1016\/j.sleep.2017.11.1142.","DOI":"10.1016\/j.sleep.2017.11.1142"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Henriksen DP, Rasmussen L, Hansen MR et al. Comparison of the five Danish regions regarding demographic characteristics, healthcare utilization, and medication use - a descriptive cross-sectional study. PLoS One. 2015;10(10):e0140197. doi: 10.1371\/journal.pone.0140197.","DOI":"10.1371\/journal.pone.0140197"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Schmidt M, Schmidt SAJ, Sandegaard JL et al. The Danish National Patient Registry: a review of content, data quality, and research potential. Clin Epidemiol. 2015;7:449-90. doi: 10.2147\/CLEP.S91125.","DOI":"10.2147\/CLEP.S91125"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Lynge E, Sandegaard JL, Rebolj M. The Danish National Patient Register. Scand J Public Health. 2011;39(7 suppl):30-3. doi: 10.1177\/1403494811401482.","DOI":"10.1177\/1403494811401482"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Sundb\u00f8ll J, Adelborg K, Munch T et al. Positive predictive value of cardiovascular diagnoses in the Danish National Patient Registry: a validation study. BMJ Open. 2016;6(11):e012832. doi: 10.1136\/bmjopen-2016-012832.","DOI":"10.1136\/bmjopen-2016-012832"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"Harris PA, Taylor R, Thielke R et al. Research electronic data capture (REDCap) - a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377-81. doi: 10.1016\/j.jbi.2008.08.010.","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"Harris PA, Taylor R, Minor BL et al. The REDCap consortium: building an international community of software platform partners. J Biomed Inform. 2019;95:103208. doi: 10.1016\/j.jbi.2019.103208.","DOI":"10.1016\/j.jbi.2019.103208"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"Wilson EB. Probable inference, the law of succession, and statistical inference. J Am Stat Assoc. 1927;22(158):209-12. doi: 10.1080\/01621459.1927.10502953.","DOI":"10.1080\/01621459.1927.10502953"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"Udholm N, Fuglsang M, Lundbye-Christensen S et al. Obstructive sleep apnea and risk of suicide and self-harm: a Danish Nationwide Cohort Study. 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