{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T12:40:01Z","timestamp":1758890401424,"version":"3.44.0"},"reference-count":5,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ugeskr L\u00e6ger"],"abstract":"<jats:p>This is a case report of a 75-year-old woman who simultaneously developed a firm tumour on the dorsum and apex of the nose. Swap for culture was negative. Punch biopsy from the dorsum and apex showed inflammation, but no foreign body reaction or malignancy. Four months after onset of the tumour, the patient developed an inflammatory reaction with pus formation and subsequent extrusion of a piece of silicone from the apex. She revealed that she 43 years prior to this incident had a rhinoplasty with a silicone implant performed. This illustrates a potential side effect to silicone implant with very late onset, manifesting as a foreign body reaction.<\/jats:p>","DOI":"10.61409\/v01250031","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T02:02:30Z","timestamp":1751421750000},"page":"1-3","source":"Crossref","is-referenced-by-count":0,"title":["Rhinoplasty with late-onset side effect to silicone implant"],"prefix":"10.61409","author":[{"given":"Martin","family":"Havmose","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrine","family":"Karmisholt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Klit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon Francis","family":"Thomsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"40208","published-online":{"date-parts":[[2025,6,30]]},"reference":[{"doi-asserted-by":"publisher","unstructured":"Kim IS. Augmentation rhinoplasty using silicone implants. Facial Plast Surg Clin North Am. 2018;26(3):285-293. https:\/\/doi.org\/10.1016\/j.fsc.2018.03.003","key":"ref0","DOI":"10.1016\/j.fsc.2018.03.003"},{"doi-asserted-by":"publisher","unstructured":"Loyo M, Ishii LE. Safety of alloplastic materials in rhinoplasty. JAMA Facial Plast Surg. 2013;15(3):162-3. https:\/\/doi.org\/10.1001\/jamafacial.2013.787","key":"ref1","DOI":"10.1001\/jamafacial.2013.787"},{"doi-asserted-by":"publisher","unstructured":"Rapaport MJ, Vinnik C, Zarem H. Injectable silicone: cause of facial nodules, cellulitis, ulceration, and migration. Aesthetic Plast Surg. 1996;20(3):267-76. https:\/\/doi.org\/10.1007\/s002669900032","key":"ref2","DOI":"10.1007\/s002669900032"},{"doi-asserted-by":"publisher","unstructured":"Pak MW, Chan ES, van Hasselt CA. Late complications of nasal augmentation using silicone implants. J Laryngol Otol. 1998;112(11):1074-7. https:\/\/doi.org\/10.1017\/s0022215100142495","key":"ref3","DOI":"10.1017\/S0022215100142495"},{"doi-asserted-by":"publisher","unstructured":"Hu HC, Fang HW, Chiu YH. Delayed-onset edematous foreign body granulomas 40 years after augmentation rhinoplasty by silicone implant combined with liquid silicone injection. Aesthetic Plast Surg. 2017;41(3):637-640. https:\/\/doi.org\/10.1007\/s00266-017-0790-6","key":"ref4","DOI":"10.1007\/s00266-017-0790-6"}],"container-title":["Ugeskrift for L\u00e6ger"],"original-title":[],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T12:16:01Z","timestamp":1758888961000},"score":1,"resource":{"primary":{"URL":"https:\/\/ugeskriftet.dk\/videnskab\/V01250031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,30]]},"references-count":5,"URL":"https:\/\/doi.org\/10.61409\/v01250031","relation":{},"ISSN":["0041-5782","1603-6824"],"issn-type":[{"type":"print","value":"0041-5782"},{"type":"electronic","value":"1603-6824"}],"subject":[],"published":{"date-parts":[[2025,6,30]]}}}