{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T12:26:32Z","timestamp":1788265592088,"version":"build-2803163510"},"reference-count":5,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ugeskr L\u00e6ger"],"abstract":"<jats:p>In this case report, a 57-year-old man with bipolar disorder on long-term lithium treatment was admitted with catatonia. Laboratory tests revealed hypercalcemia with parathyroid hormone levels in the upper third of the normal reference interval, consistent with lithium-associated hyperparathyroidism, as well as nephrogenic diabetes insipidus. Pausing lithium and treating hypercalcemia led to a gradual improvement in catatonia. The case emphasises the importance of considering endocrine and electrolyte disturbances in cases of acute deterioration of psychiatric symptoms during lithium treatment.<\/jats:p>","DOI":"10.61409\/v01260006","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T06:03:01Z","timestamp":1786341781000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["Lithium-induced electrolyte disturbances and catatonia"],"prefix":"10.61409","author":[{"given":"Hjalte","family":"Knudsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torben Albert","family":"Devantier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren Dinesen","family":"\u00d8stergaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torben","family":"Harsl\u00f8f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esben Stistrup","family":"Lauritzen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"40208","published-online":{"date-parts":[[2026,8,10]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Trepiccione F, Christensen BM. Lithium-induced nephrogenic diabetes insipidus: new clinical and experimental findings. J Nephrol. 2010;23 Suppl 16:S43-8","DOI":"10.1093\/joneph\/23.S16.S43"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Vandermeulen L, Van Melkebeke L, Sienaert P. Lithium-associated hypercalcemia and hyperparathyroidism: a systematic review and meta-analysis. World J Biol Psychiatry. 2024;25(8):417-429. https:\/\/doi.org\/10.1080\/15622975.2024.2393373","DOI":"10.1080\/15622975.2024.2393373"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Thippaiah SM, Fargason RE, Gude JG et al. Lithium-associated hyperparathyroidism followed by catatonia. AACE Clin Case Rep. 2021;7(3):189-191. https:\/\/doi.org\/10.1016\/j.aace.2020.12.010","DOI":"10.1016\/j.aace.2020.12.010"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Kovacs Z, Vestergaard P, Licht RW et al. Lithium induced hypercalcemia: an expert opinion and management algorithm. Int J Bipolar Disord. 2022;10(1):34. https:\/\/doi.org\/10.1186\/s40345-022-00283-3","DOI":"10.1186\/s40345-022-00283-3"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Lu B, Zhang Q, Wang H et al. Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex. Neuron. 2010;68(3):488-99. https:\/\/doi.org\/10.1016\/j.neuron.2010.09.014","DOI":"10.1016\/j.neuron.2010.09.014"}],"container-title":["Ugeskrift for L\u00e6ger"],"original-title":[],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T12:12:06Z","timestamp":1788264726000},"score":1,"resource":{"primary":{"URL":"https:\/\/ugeskriftet.dk\/videnskab\/V01260006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,10]]},"references-count":5,"URL":"https:\/\/doi.org\/10.61409\/v01260006","relation":{},"ISSN":["0041-5782","1603-6824"],"issn-type":[{"value":"0041-5782","type":"print"},{"value":"1603-6824","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,10]]}}}