{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T13:10:59Z","timestamp":1761225059020,"version":"build-2065373602"},"reference-count":5,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ugeskr L\u00e6ger"],"abstract":"<jats:p>Unilateral tongue angioedema is a rare condition with potential risk of airway obstruction. This case report presents a 71-year-old woman with acute coronary syndrome who developed unilateral tongue swelling one hour after administration of acetylsalicylic acid (ASA). The symptoms resolved after treatment with glucocorticoid and an antihistamine, suggesting a histamine-mediated mechanism. Only one previous case of ASA-induced unilateral tongue angioedema has been described in the literature (2006). Early recognition and discontinuation of the triggering drug is essential, and allergy testing should be considered.<\/jats:p>","DOI":"10.61409\/v03250174","type":"journal-article","created":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T12:44:26Z","timestamp":1761137066000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["Unilateral tongue angioedema induced by acetylsalicylic acid"],"prefix":"10.61409","author":[{"given":"Andreina","family":"Sonntag","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie Christine","family":"Gaardbo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"40208","published-online":{"date-parts":[[2025,10,20]]},"reference":[{"doi-asserted-by":"publisher","unstructured":"Ishoo E, Shah UK, Grillone GA et al. Predicting airway risk in angioedema: staging system based on presentation. Otolaryngol Head Neck Surg. 1999;121(3):263-8. https:\/\/doi.org\/10.1016\/S0194-5998(99)70182-8","key":"ref0","DOI":"10.1016\/S0194-5998(99)70182-8"},{"doi-asserted-by":"publisher","unstructured":"Kaptanoglu AF, Aytas H. Aspirin-induced unilateral angioedema of the tongue. J Eur Acad Dermatol Venereol. 2006;20(5):617-8. https:\/\/doi.org\/10.1111\/j.1468-3083.2006.01501.x","key":"ref1","DOI":"10.1111\/j.1468-3083.2006.01501.x"},{"doi-asserted-by":"publisher","unstructured":"Hahn J, Hoffmann TK, Bock B et al. Angioedema. Dtsch Arztebl Int. 2017;114(29-30):489-496. https:\/\/doi.org\/10.3238\/arztebl.2017.0489","key":"ref2","DOI":"10.3238\/arztebl.2017.0489"},{"doi-asserted-by":"publisher","unstructured":"Matsuhisa Y, Kenzaka T, Shimizu H et al. Recurrence of unilateral angioedema of the tongue: a case report. World J Clin Cases. 2023;11(27):6603-6612. https:\/\/doi.org\/10.12998\/wjcc.v11.i27.6603","key":"ref3","DOI":"10.12998\/wjcc.v11.i27.6603"},{"doi-asserted-by":"publisher","unstructured":"Lee JE, Bryant SM. Unilateral angioedema. Am J Emerg Med. 2021;49:302-303. https:\/\/doi.org\/10.1016\/j.ajem.2021.06.040","key":"ref4","DOI":"10.1016\/j.ajem.2021.06.040"}],"container-title":["Ugeskrift for L\u00e6ger"],"original-title":[],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T12:48:04Z","timestamp":1761223684000},"score":1,"resource":{"primary":{"URL":"https:\/\/ugeskriftet.dk\/videnskab\/V03250174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,20]]},"references-count":5,"URL":"https:\/\/doi.org\/10.61409\/v03250174","relation":{},"ISSN":["0041-5782","1603-6824"],"issn-type":[{"type":"print","value":"0041-5782"},{"type":"electronic","value":"1603-6824"}],"subject":[],"published":{"date-parts":[[2025,10,20]]}}}