{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:56:09Z","timestamp":1773968169619,"version":"3.50.1"},"reference-count":4,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ugeskr L\u00e6ger"],"abstract":"<jats:p>Polypharmacy is common among the elderly. This case report details the experience of an 85-year-old man whose notable polypharmacy and additional over-the-counter medicines led to anemia and acute kidney injury. These issues were traced to an unintended \u00bbtriple-whammy\u00ab effect due to the interaction of diuretics, ACE inhibitors, and NSAIDs, and concurrent treatment with an anticoagulant. Highlighting the role of systematic medication reviews, this case illustrates how targeted interventions can prevent severe health outcomes and underscores the importance of medication monitoring in elderly patients.<\/jats:p>","DOI":"10.61409\/v04250337","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T07:46:54Z","timestamp":1773301614000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Medication review in a geriatric patient with inappropriate polypharmacy"],"prefix":"10.61409","author":[{"given":"Frederik Viggo Lautrup","family":"Esmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle Wulff","family":"\u00d8sterskov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David Peick","family":"Sonne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Horwitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ida Marie","family":"Heerfordt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"40208","published-online":{"date-parts":[[2026,3,2]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Prieto-Garc\u00eda L, Pericacho M, Sancho-Mart\u00ednez SM et al. Mechanisms of triple whammy acute kidney injury. Pharmacol Ther. 2016;167:132-145. https:\/\/doi.org\/10.1016\/j.pharmthera.2016.07.011","DOI":"10.1016\/j.pharmthera.2016.07.011"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Hansen RN, Burghle A, Gr\u00fcnfeld SB et al. Counselling customers at risk of the triple whammy effect at community pharmacies - a feasibility study. Explor Res Clin Soc Pharm. 2023;12:100339. https:\/\/doi.org\/10.1016\/j.rcsop.2023.100339","DOI":"10.1016\/j.rcsop.2023.100339"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Hansen ML, S\u00f8rensen R, Clausen MT et al. Risk of bleeding with single, dual, or triple therapy with warfarin, aspirin, and clopidogrel in patients with atrial fibrillation. Arch Intern Med. 2010;170(16):1433-41. https:\/\/doi.org\/10.1001\/archinternmed.2010.271","DOI":"10.1001\/archinternmed.2010.271"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"B\u00fclow C, Noergaard JDSV, Faerch KU et al. Causes of discrepancies between medications listed in the national electronic prescribing system and patients' actual use of medications. Basic Clin Pharmacol Toxicol. 2021;129(3):221-231. https:\/\/doi.org\/10.1111\/bcpt.13626","DOI":"10.1111\/bcpt.13626"}],"container-title":["Ugeskrift for L\u00e6ger"],"original-title":[],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T13:06:01Z","timestamp":1773925561000},"score":1,"resource":{"primary":{"URL":"https:\/\/ugeskriftet.dk\/videnskab\/V04250337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,2]]},"references-count":4,"URL":"https:\/\/doi.org\/10.61409\/v04250337","relation":{},"ISSN":["0041-5782","1603-6824"],"issn-type":[{"value":"0041-5782","type":"print"},{"value":"1603-6824","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,2]]}}}