{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T12:37:25Z","timestamp":1761223045663,"version":"build-2065373602"},"reference-count":26,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ugeskr L\u00e6ger"],"abstract":"<jats:p>Septal deviation is one of the most frequent causes of nasal obstruction. Septal deviation may result from trauma, congenital malformations, or age-related changes, and symptoms include impaired nasal airflow, snoring, and poor sleep quality. Septoplasty is the standard treatment. The procedure is generally safe and improves quality of life for most patients, though recurrence of symptoms is not uncommon. Careful patient selection and preoperative evaluation are key to optimizing surgical outcomes as argued in this review.<\/jats:p>","DOI":"10.61409\/v04250353","type":"journal-article","created":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T07:01:56Z","timestamp":1761116516000},"page":"1-9","source":"Crossref","is-referenced-by-count":0,"title":["Septal deviation"],"prefix":"10.61409","author":[{"given":"Kumanan Rune","family":"Nanthan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Skala Dehlair","family":"Kalid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Schousboe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth Stockman","family":"Larsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bibi","family":"Lange","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas Hjelm","family":"Wernberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gita","family":"J\u00f8rgensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anette Dr\u00f8hse","family":"Kjeldsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"40208","published-online":{"date-parts":[[2025,10,13]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Schwentner I, Dejakum K, Schmutzhard J, et al. Does nasal septal surgery improve quality of life? Acta Otolaryngol 2006;126:752-757. https:\/\/doi.org\/10.1080\/00016480500504176","DOI":"10.1080\/00016480500504176"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Moore M, Eccles R. Objective evidence for the efficacy of surgical management of the deviated septum as a treatment for chronic nasal obstruction: a systematic review. Clin Otolaryngol 2011;36(2):106-113. https:\/\/doi.org\/10.1111\/j.1749-4486.2011.02279.x","DOI":"10.1111\/j.1749-4486.2011.02279.x"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Mladina R, \u010cuji\u0107 E, \u0160ubari\u0107 M, et al. Nasal septal deformities in ear, nose, and throat patients. Am J Otolaryngol. 2008;29:75-82. https:\/\/doi.org\/10.1016\/j.amjoto.2007.02.002","DOI":"10.1016\/j.amjoto.2007.02.002"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Bredahl J\u00d8, R\u00f8nnegaard AB, Larsen KS, et al. High validity and completeness of the septoplasty surgical procedure code in the Danish National Patient Registry. Clin Epidemiol. 2025;17:435-440. https:\/\/doi.org\/10.2147\/CLEP.S493386","DOI":"10.2147\/CLEP.S493386"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Holt GR. Biomechanics of nasal septal trauma. Otolaryngol Clin North Am. 1999;32(4):615-619. https:\/\/doi.org\/10.1016\/S0030-6665(05)70159-6","DOI":"10.1016\/S0030-6665(05)70159-6"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Gray LP. Deviated nasal septum incidence and etiology. Ann Otol Rhinol Laryngol Suppl. 1978;87(3 Pt 3 Suppl 50):3-20. https:\/\/doi.org\/10.1177\/00034894780873S201","DOI":"10.1177\/00034894780873S201"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Kim IS, Lee MY, Lee KI, et al. Analysis of the development of the nasal septum according to age and gender using MRI. Clin Exp Otorhinolaryngol. 2008;1(1):29-34. https:\/\/doi.org\/10.3342\/ceo.2008.1.1.29","DOI":"10.3342\/ceo.2008.1.1.29"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Munksgaard JB, Christensen JJ, Aan\u00e6s K. Rhinitis medicamentosa. Ugeskr L\u00e6ger 2024;186:V04240252. https:\/\/doi.org\/10.61409\/V04240252","DOI":"10.61409\/V04240252"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Sandham A, Murray JA. Nasal septal deformity in unilateral cleft lip and palate. Cleft Palate Craniofac J. 1993;30(2):222-226. https:\/\/doi.org\/10.1597\/1545-1569_1993_030_0222_nsdiuc_2.3.co_2","DOI":"10.1597\/1545-1569_1993_030_0222_nsdiuc_2.3.co_2"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"Huizing EH, de Groot JAM, Hellings PW, Bleys RLAW. Functional Reconstructive Nasal Surgery. Thieme; 2015. https:\/\/doi.org\/10.1055\/b-0035-121531","DOI":"10.1055\/b-0035-121531"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"Behnke J, Dundervill C, Bulbul M, et al. Using the sino-nasal outcome test (SNOT-22) to study outcome of treatment of nasal obstruction. Am J Otolaryngol. 2023;44(4):103879. https:\/\/doi.org\/10.1016\/j.amjoto.2023.103879","DOI":"10.1016\/j.amjoto.2023.103879"},{"key":"ref11","unstructured":"Lange B, Thilsing T, Al-kalemji A, et al. The Sino-Nasal Outcome Test 22 validated for Danish patients. Dan Med Bull. 2011;58(2):A4235. https:\/\/ugeskriftet.dk\/dmj\/sino-nasal-outcome-test-22-validated-danish-patients"},{"key":"ref12","unstructured":"Skansing DB, Mand\u00f8 M, Holte MB, et al. Vurdering af n\u00e6sens funktion ved computational fluid dynamics. Ugeskr L\u00e6ger. 2022;184:V06210516. Vurdering af n\u00e6sens funktion ved computational fluid dynamics | Ugeskriftet.dk"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"Aziz T, Biron VL, Ansari K, et al. Measurement tools for the diagnosis of nasal septal deviation: a systematic review. J Otolaryngol Head Neck Surg. 2014;43(1):11. https:\/\/doi.org\/10.1186\/1916-0216-43-11","DOI":"10.1186\/1916-0216-43-11"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"Cingi C, Ozdoganoglu T, Songu M. Nasal obstruction as a drug side effect. Ther Adv Respir Dis. 2011;5(3):175-182. https:\/\/doi.org\/10.1177\/1753465811403348","DOI":"10.1177\/1753465811403348"},{"key":"ref15","unstructured":"Watters C, Brar S, Yapa S. Septoplasty. I: StatPearls. Treasure Island (FL). StatPearls Publishing. 2022. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK567718\/"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"Slavin SA, Goldwyn RM. The cocaine user: the potential problem patient for rhinoplasty. Plast Reconstr Surg. 1990;86(3):436-442. https:\/\/doi.org\/10.1097\/00006534-199009000-00008","DOI":"10.1097\/00006534-199009000-00008"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"Ricci G, D'Ascanio L. Antibiotics in septoplasty: evidence or habit? Am J Rhinol Allergy. 2012;26(3):194-196. https:\/\/doi.org\/10.2500\/ajra.2012.26.3755","DOI":"10.2500\/ajra.2012.26.3755"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"Bloom JD, Kaplan SE, Bleier BS, et al. Septoplasty complications: avoidance and management. Otolaryngol Clin North Am. 2009;42(3):463-481. https:\/\/doi.org\/10.1016\/j.otc.2009.04.011","DOI":"10.1016\/j.otc.2009.04.011"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"Carrie S, O'Hara J, Fouweather T, et al. Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial. BMJ. 2023;383:e075445. https:\/\/doi.org\/10.1136\/bmj-2023-075445","DOI":"10.1136\/bmj-2023-075445"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"Van Egmond MMHT, Rovers MM, Hannink G, et al. Septoplasty with or without concurrent turbinate surgery versus non-surgical management for nasal obstruction in adults with a deviated septum: a pragmatic, randomised controlled trial. Lancet. 2019;394(10195):314-321. https:\/\/doi.org\/10.1016\/S0140-6736(19)30354-X","DOI":"10.1016\/S0140-6736(19)30354-X"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"Tsang CLN, Nguyen T, Sivesind T, et al. Long-term patient-related outcome measures of septoplasty: a systematic review. Eur Arch Otorhinolaryngol. 2018;275(5):1039-1048. https:\/\/doi.org\/10.1007\/s00405-018-4874-y","DOI":"10.1007\/s00405-018-4874-y"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"Valsamidis K, Titelis K, Rachovitsas D, et al. Long-term evaluation of nasal septoplasty followed by inferior turbinate cauterization for the treatment of nasal obstruction using objective and subjective methods. Int Arch Otorhinolaryngol. 2018;22(3):284-290. https:\/\/doi.org\/10.1055\/s-0037-1613688","DOI":"10.1055\/s-0037-1613688"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"Toyserkani NM, Frisch T. Are too many septal deviations operated on? A retrospective patient's satisfaction questionnaire with 11 years follow-up. Rhinology. 2012;50(2):185-190. https:\/\/doi.org\/10.4193\/rhino11.218","DOI":"10.4193\/Rhino11.218"},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"Pedersen L, Schi\u00f6ler L, Holmberg K, et al. Age and unplanned postoperative visits predict outcome after septoplasty: a national Swedish register study. Int J Otolaryngol 2018;2018:2379536. https:\/\/doi.org\/10.1155\/2018\/2379536","DOI":"10.1155\/2018\/2379536"},{"key":"ref25","doi-asserted-by":"publisher","unstructured":"Pedersen L, Schi\u00f6ler L, Finjan S, et al. Prognostic factors for outcome after septoplasty in 888 patients from the Swedish National Septoplasty Register. Eur Arch Otorhinolaryngol. 2019;276(8):2223-2228. https:\/\/doi.org\/10.1007\/s00405-019-05440-6","DOI":"10.1007\/s00405-019-05440-6"}],"container-title":["Ugeskrift for L\u00e6ger"],"original-title":[],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T12:06:02Z","timestamp":1761221162000},"score":1,"resource":{"primary":{"URL":"https:\/\/ugeskriftet.dk\/videnskab\/V04250353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,13]]},"references-count":26,"URL":"https:\/\/doi.org\/10.61409\/v04250353","relation":{},"ISSN":["0041-5782","1603-6824"],"issn-type":[{"type":"print","value":"0041-5782"},{"type":"electronic","value":"1603-6824"}],"subject":[],"published":{"date-parts":[[2025,10,13]]}}}