{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T14:03:14Z","timestamp":1773151394184,"version":"3.50.1"},"reference-count":5,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ugeskr L\u00e6ger"],"abstract":"<jats:p>Fetal intracranial immature teratomas are extremely rare, rapidly growing and associated with high mortality. We present a case of a large immature intracranial teratoma diagnosed at gestational week 29 with associated macrocephaly and orbital involvement. Due to the tumour size and lethality, cesarean delivery was performed. The neonate died shortly after birth. Postmortem examination and histology confirmed an immature teratoma without somatic-type malignancy. The recurrence risk is considered extremely low.<\/jats:p>","DOI":"10.61409\/v05250364","type":"journal-article","created":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T12:44:26Z","timestamp":1761137066000},"page":"1-3","source":"Crossref","is-referenced-by-count":1,"title":["Fetal intracranial immature teratoma"],"prefix":"10.61409","author":[{"given":"Christoffer Skov","family":"Olesen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian Rafn","family":"Hjelvang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian Beltoft","family":"Br\u00f8chner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa Leth","family":"Maroun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Finn Stener","family":"J\u00f8rgensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"40208","published-online":{"date-parts":[[2025,10,20]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Robles Fradejas M, Gonzalo Garc\u00eda I, De las Casas Quispe AC, et al. Fetal intracranial immature teratoma: presentation of a case and a systematic review of the literature. J Matern Fetal Neonatal Med. 2017;30(10):1139-1146. https:\/\/doi.org\/10.1080\/14767058.2016.1205029","DOI":"10.1080\/14767058.2016.1205029"},{"key":"ref1","unstructured":"WHO. Germ cell tumours of the CNS. I: Central Nervous System Tumours, 5th ed. Vol 6, 2021. https:\/\/publications.iarc.who.int\/Book-And-Report-Series\/Who-Classification-Of-Tumours\/Central-Nervous-System-Tumours-2021"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Gkasdaris G, Chourmouzi D. Congenital intracranial mature teratoma: the role of fetal MRI over ultrasound in the prenatal diagnosis and the perinatal management. BMJ Case Rep. 2019;12(5):e229774. https:\/\/doi.org\/10.1136\/bcr-2019-229774","DOI":"10.1136\/bcr-2019-229774"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Abiad M, Zargarzadeh N, Javinani A, et al. Fetal teratomas: advances in diagnosis and management. J Clin Med. 2024;13(20):6245. https:\/\/doi.org\/10.3390\/jcm13206245","DOI":"10.3390\/jcm13206245"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Carstensen H, Juhler M, B\u00f8geskov L, Laursen H. A report of nine newborns with congenital brain tumours. Childs Nerv Syst. 2006;22(11):1427-1431. https:\/\/doi.org\/10.1007\/s00381-006-0115-6","DOI":"10.1007\/s00381-006-0115-6"}],"container-title":["Ugeskrift for L\u00e6ger"],"original-title":[],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T12:51:42Z","timestamp":1761223902000},"score":1,"resource":{"primary":{"URL":"https:\/\/ugeskriftet.dk\/videnskab\/V05250364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,20]]},"references-count":5,"URL":"https:\/\/doi.org\/10.61409\/v05250364","relation":{},"ISSN":["0041-5782","1603-6824"],"issn-type":[{"value":"0041-5782","type":"print"},{"value":"1603-6824","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,20]]}}}