{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T13:10:48Z","timestamp":1763644248321,"version":"3.45.0"},"reference-count":5,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ugeskr L\u00e6ger"],"abstract":"<jats:p>Autoimmune progesterone dermatitis (APD) is a rare, cyclic condition triggered by sensitisation to exogenous and\/or endogenous progesterone. In this case report, we present a 44-year-old woman with presumed primary sensitisation from an intrauterine device, followed by cross-reactivity to endogenous progesterone. The patient experienced significant symptom relief following treatment with omalizumab. In conclusion, APD is diagnostically challenging due to its variable presentation, but treatment with omalizumab has shown promising results.<\/jats:p>","DOI":"10.61409\/v06250533","type":"journal-article","created":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T13:19:06Z","timestamp":1763558346000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["Autoimmune progesterone dermatitis"],"prefix":"10.61409","author":[{"given":"Johanna","family":"Larsson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristian Fredl\u00f8v","family":"Mose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anette","family":"Bygum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"40208","published-online":{"date-parts":[[2025,11,17]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Buchheit KM, Bernstein JA. Progestogen hypersensitivity: heterogeneous manifestations with a common trigger. J Allergy Clin Immunol Pract. 2017;5(3):566-574. https:\/\/doi.org\/10.1016\/j.jaip.2017.01.019","DOI":"10.1016\/j.jaip.2017.01.019"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Nguyen T, Ahmed AR. Autoimmune progesterone dermatitis: update and insights. Autoimmun Rev. 2016;15(2):191-7. https:\/\/doi.org\/10.1016\/j.autrev.2015.11.003","DOI":"10.1016\/j.autrev.2015.11.003"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Warin AP. Case 2. Diagnosis: erythema multiforme as a presentation of autoimmune progesterone dermatitis. Clin Exp Dermatol. 2001;26(1):107-8. https:\/\/doi.org\/10.1046\/j.1365-2230.2001.00747.x","DOI":"10.1046\/j.1365-2230.2001.00747.x"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Varghese A, Paul T, Kim H et al. Effect of omalizumab for autoimmune progesterone dermatitis refractory to bilateral oophorectomy: a case report. Allergy Asthma Clin Immunol. 2021;17(1):58. https:\/\/doi.org\/10.1186\/s13223-021-00561-2","DOI":"10.1186\/s13223-021-00561-2"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Herzberg AJ, Strohmeyer CR, Cirillo-Hyland VA. Autoimmune progesterone dermatitis. J Am Acad Dermatol. 1995;32(2 Pt 2):333-8. https:\/\/doi.org\/10.1016\/0190-9622(95)90398-4","DOI":"10.1016\/0190-9622(95)90398-4"}],"container-title":["Ugeskrift for L\u00e6ger"],"original-title":[],"deposited":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T12:58:47Z","timestamp":1763643527000},"score":1,"resource":{"primary":{"URL":"https:\/\/ugeskriftet.dk\/videnskab\/V06250533"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,17]]},"references-count":5,"URL":"https:\/\/doi.org\/10.61409\/v06250533","relation":{},"ISSN":["0041-5782","1603-6824"],"issn-type":[{"type":"print","value":"0041-5782"},{"type":"electronic","value":"1603-6824"}],"subject":[],"published":{"date-parts":[[2025,11,17]]}}}