{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T02:28:19Z","timestamp":1744079299162},"reference-count":5,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ugeskr L\u00e6ger"],"abstract":"<jats:p>Cytomegalovirus infection (CMV) can be fatal for organ transplant recipients as shown in this case report. Maribavir is a recently approved drug, which can be used for therapy-refractory CMV infection or when other treatment options cannot be used. The patient in this case report was a CMV-infected liver transplant recipient, who developed a severe erythema and high CMV DNA during valganciclovir therapy. Toxic epidermal necrolysis was suspected. The patient was treated with maribavir, and both CMV DNA and the skin normalised. This case illustrates that maribavir is a useful alternative to other antiviral drugs for CMV infection.<\/jats:p>","DOI":"10.61409\/v11230726","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T10:17:18Z","timestamp":1713176238000},"page":"1-Josefine Amalie","source":"Crossref","is-referenced-by-count":1,"title":["Maribavir for treatment of cytomegalovirus infection in a liver-transplanted patient"],"prefix":"10.61409","volume":"186","author":[{"given":"Josefine Amalie","family":"Loft","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter Theut","family":"Riis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolai Aagaard","family":"Schultz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Bjerrum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristian","family":"Sch\u00f8nning","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian Ross","family":"Pedersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul Suno","family":"Krohn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne Dam","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"40208","published-online":{"date-parts":[[2024,4,8]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Kotton CN, Kumar D, Caliendo AM, et al. The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-organ Transplantation. Transplantation. 2018;102(6):900-31. doi: https:\/\/doi.org\/10.1097\/TP.0000000000002191","DOI":"10.1097\/TP.0000000000002191"},{"key":"ref1","unstructured":"Medicinr\u00e5det. Medicinr\u00e5dets anbefaling vedr. maribavir til behandling af refrakt\u00e6r CMV-infektion (med eller uden resistens), 2023. https:\/\/medicinraadet.dk\/media\/5aijosrs\/medicinr\u00e5dets-anbefaling-vedr-maribavir-til-refrakt\u00e6r-cmv-infektion-vers-1-0-x.pdf (21. nov 2023)."},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Razonable RR. Oral antiviral drugs for treatment of cytomegalovirus in transplant recipients. Clin Microbiol Infect. 2023;29(9):1144-9. doi: https:\/\/doi.org\/10.1016\/j.cmi.2023.03.020","DOI":"10.1016\/j.cmi.2023.03.020"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Khalaf D, Toema B, Dabbour N et al. Toxic epidermal necrolysis associated with severe cytomegalovirus infection in a patient on regular hemodialysis. Mediterr J Hematol Infect Dis. 2011;3(1):e 2011004. doi: https:\/\/doi.org\/10.4084\/mjhid.2010.004","DOI":"10.4084\/mjhid.2010.004"},{"key":"ref4","unstructured":"Trayes KP, Love G, Studdiford JS. Erythema multiforme: recognition and management. Am Fam Physician. 2019;100(2):8288."}],"container-title":["Ugeskrift for L\u00e6ger"],"original-title":[],"deposited":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T06:09:05Z","timestamp":1715839745000},"score":1,"resource":{"primary":{"URL":"https:\/\/ugeskriftet.dk\/videnskab\/V11230726"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,8]]},"references-count":5,"URL":"https:\/\/doi.org\/10.61409\/v11230726","relation":{},"ISSN":["0041-5782","1603-6824"],"issn-type":[{"value":"0041-5782","type":"print"},{"value":"1603-6824","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,8]]}}}