{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T18:57:58Z","timestamp":1754161078645,"version":"3.41.2"},"reference-count":5,"publisher":"Danish Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ugeskr L\u00e6ger"],"abstract":"<jats:p>Anaplasmosis is caused by the tick-borne bacterium Anaplasma phagocytophilum. In this case report, a 73-year-old immunocompetent male was admitted with high fever, headache and fatigue following a tick bite. The patient had hyperinflammation and an intense 18F-fluordeoxyglucose uptake in the spleen and bone marrow. The patient\u2019s symptoms subsided without specific treatment. A. phagocytophilum was identified by use of amplicon-based 16S\/18S rDNA next generation-sequencing of DNA extracted from ethylenediamine tetraacetic (EDTA) blood. This test may serve a role in the diagnosis of fever following tick bite in the future.<\/jats:p>","DOI":"10.61409\/v11240774","type":"journal-article","created":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T06:10:50Z","timestamp":1740982250000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["Anaplasmosis imitating haematological disease with hyperinflammation"],"prefix":"10.61409","author":[{"given":"Christian S.","family":"Benson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Porskrog","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rune","family":"Stensvold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik Vedel","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina Schjellerup","family":"Eickhardt-Dalb\u00f8ge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"40208","published-online":{"date-parts":[[2025,3,3]]},"reference":[{"key":"ref0","unstructured":"Jensen BB, Ocias LF, Andersen NS et al. Fl\u00e5tb\u00e5rne infektioner i Danmark. Ugeskr L\u00e6ger. 2017;179:V01170027"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Schudel S, Gygax L, Kositz C et al. Human granulocytotropic anaplasmosis - a systematic review and analysis of the literature. PLoS Negl Trop Dis. 2024;18(8): e0012313. https:\/\/doi.org\/10.1371\/journal.pntd.0012313","DOI":"10.1371\/journal.pntd.0012313"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Quarsten H, Henningsson A, Krogfelt KA et al. Tick-borne diseases under the radar in the North Sea Region. Ticks Tick Borne Dis. 2023;14(4):102185. https:\/\/doi.org\/10.1016\/j.ttbdis.2023.102185","DOI":"10.1016\/j.ttbdis.2023.102185"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Skarph\u00e9dinsson S, Lyholm BF, Ljungberg M et al. Detection and identification of Anaplasma phagocytophilum, Borrelia burgdorferi, and Rickettsia Helvetica in Danish Ixodes ricinus ticks. APMIS. 2007; 115(3):225-30. https:\/\/doi.org\/10.1111\/j.1600-0463.2007.apm_256.x","DOI":"10.1111\/j.1600-0463.2007.apm_256.x"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Holmgaard DB, Barnadas C, Mirbarati SH et al. Detection and identification of Acanthamoeba and other nonviral causes of infectious keratitis in corneal scrapings by real-time PCR and next-generation sequencing-based 16S-18S gene analysis. J Clin Microbiol. 2021;59(2):e02224-20. https:\/\/doi.org\/10.1128\/JCM.02224-20","DOI":"10.1128\/JCM.02224-20"}],"container-title":["Ugeskrift for L\u00e6ger"],"original-title":[],"deposited":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T13:35:46Z","timestamp":1753709746000},"score":1,"resource":{"primary":{"URL":"https:\/\/ugeskriftet.dk\/videnskab\/V11240774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,3]]},"references-count":5,"URL":"https:\/\/doi.org\/10.61409\/v11240774","relation":{},"ISSN":["0041-5782","1603-6824"],"issn-type":[{"type":"print","value":"0041-5782"},{"type":"electronic","value":"1603-6824"}],"subject":[],"published":{"date-parts":[[2025,3,3]]}}}