{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T00:29:06Z","timestamp":1717720146829},"reference-count":0,"publisher":"SWISS DENTAL JOURNAL SSO","issue":"12","license":[{"start":{"date-parts":[[2022,12,5]],"date-time":"2022-12-05T00:00:00Z","timestamp":1670198400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Swiss Dent. J. SSO"],"abstract":"<jats:p>Wir berichten von einem 64-j\u00e4hrigen Patienten mit Zufallsbefund einer unilokul\u00e4ren Radioluzenz in regio 48 im apikalen R\u00f6ntgen. Im Biopsat (Zystostomie) fand sich der aussergew\u00f6hnliche Befund eines prim\u00e4r intraoss\u00e4ren Mukoepider-moidkarzinoms; dies ist mit 2 bis 4% der ektopen Manifestationen dieser Entit\u00e4t eine Rarit\u00e4t. Molekularpathologische Untersuchungen mit spezifischem Panel (SalvGlandDx) und FISH erbrachten den diagnosesichernden Nachweis der CRTC1- MAML2-Fusion. Es erfolgte die Kastenresektion, prophylaktische Osteosynthese mittels patientenspezifischer Rekonstruktionsplatte, Neck Dissection und lokale Deckung mittels Bichat- Lappen gem\u00e4ss interdisziplin\u00e4rem Tumorboardentscheid. Bei tumorfreien Lymphknoten und R0-Resektion war keine adjuvante Therapie erforderlich. Klinische und bildgebende Nachsorge \u00fcber nun 24 Monate zeigten keine Hinweise auf ein lokoregion\u00e4res Rezidiv. Die vorgestellte Kasuistik betont die zentrale Rolle der zahn\u00e4rztlichen Privatpraxen in der Fr\u00fcherkennung oraler Mali- gnome. Diese sollten in der Differenzialdiagnostik zystischer L\u00e4sionen stets bedacht werden.<\/jats:p>","DOI":"10.61872\/sdj-2022-12-02","type":"journal-article","created":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T13:57:06Z","timestamp":1709301426000},"page":"849-854","source":"Crossref","is-referenced-by-count":0,"title":["Eine radioluzente Rarit\u00e4t: Prim\u00e4r intraoss\u00e4res Mukoepidermoidkarzinom des posterioren Unterkiefers: vom r\u00f6ntgenologischen Zufallsbefund zur molekularpathologischen Diagnose","A radiolucent rarity - primary intraosseous mucoepidermoid carcinoma of the posterior mandible: From radiographic incidental finding to molecular pathological diagnosis"],"prefix":"10.61872","volume":"132","author":[{"given":"Martina C.","family":"Schwerzmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daphne","family":"Sch\u00f6negg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Linden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann-Katrin","family":"Rodewald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Gander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Lanzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"48141","published-online":{"date-parts":[[2022,12,5]]},"container-title":["SWISS DENTAL JOURNAL SSO \u2013 Science and Clinical Topics"],"original-title":[],"link":[{"URL":"https:\/\/www.swissdentaljournal.org\/article\/download\/4960\/3605","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.swissdentaljournal.org\/article\/download\/4960\/3605","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T12:46:34Z","timestamp":1717677994000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.swissdentaljournal.org\/article\/view\/4960"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,5]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12,5]]}},"URL":"https:\/\/doi.org\/10.61872\/sdj-2022-12-02","relation":{},"ISSN":["2296-6501","2296-6498"],"issn-type":[{"value":"2296-6501","type":"electronic"},{"value":"2296-6498","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12,5]]}}}