{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:25:15Z","timestamp":1792013115877,"version":"4.4.0"},"reference-count":91,"publisher":"National Academy of Sciences of Tajikistan","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IBJ"],"DOI":"10.61882\/ibj.4960","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T15:16:38Z","timestamp":1765379798000},"page":"173-188","source":"Crossref","is-referenced-by-count":13,"title":["Optimizing Cancer Treatment: A Comprehensive Review of Active and Passive Drug Delivery Strategies"],"prefix":"10.61882","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8038-036X","authenticated-orcid":false,"given":"Parastoo","family":"Tarighi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3888-5671","authenticated-orcid":false,"given":"Mona","family":"Mousavi Esfahani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7607-4041","authenticated-orcid":false,"given":"Ali","family":"Emamjomeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7599-018X","authenticated-orcid":false,"given":"Zohreh","family":"Mirjalili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0075-8810","authenticated-orcid":false,"given":"Parastoo","family":"Mirzabeygi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"48150","published-online":{"date-parts":[[2025,4,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4103\/2230-973X.96920"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25020786"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3389\/fddsv.2023.1201419"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics11030140"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26195905"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjbs.2022.103298"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s10311-018-00841-1"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-022-01320-5"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3390\/jpm11080771"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13040670"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.7150\/thno.39560"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15092233"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.3390\/jpm11060571"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1039\/D1BM01398J"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2023.106688"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241210082"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S293427"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-025-03252-x"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2022.114449"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.18433\/jpps30583"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1007\/s10311-020-01022-9"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2022-0257"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.3390\/ph14080725"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmt.2023.09.001"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-819943-5.00003-8"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2023.121669"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics11050230"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.10.003"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2020.112229"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.3c00705"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.1024143"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmt.2022.11.011"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2018.02.017"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.25961"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2018.04.012"},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19020255"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15030774"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.4236\/jbm.2025.132028"},{"key":"ref77","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01536-y"},{"key":"ref79","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-33-4497-6_1"},{"key":"ref81","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-97-3545-7_9"},{"key":"ref83","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajps.2022.11.002"},{"key":"ref85","doi-asserted-by":"publisher","DOI":"10.20517\/cdr.2020.68"},{"key":"ref87","doi-asserted-by":"publisher","DOI":"10.18178\/ijpmbs.10.1.23-29"},{"key":"ref89","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057522"},{"key":"ref91","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2007.223"},{"key":"ref93","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S234112"},{"key":"ref95","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.35088"},{"key":"ref97","doi-asserted-by":"publisher","DOI":"10.1111\/jphp.13098"},{"key":"ref99","doi-asserted-by":"publisher","DOI":"10.3390\/antib9030034"},{"key":"ref101","doi-asserted-by":"publisher","DOI":"10.1016\/j.nanoso.2019.100370"},{"key":"ref103","doi-asserted-by":"publisher","DOI":"10.34172\/PS.2021.75"},{"key":"ref105","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.112260"},{"key":"ref107","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1736"},{"key":"ref109","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-022-00947-7"},{"key":"ref111","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.671"},{"key":"ref113","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-021-01459-y"},{"key":"ref115","doi-asserted-by":"publisher","DOI":"10.3390\/genes13112065"},{"key":"ref117","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15153886"},{"key":"ref119","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.112232"},{"key":"ref121","doi-asserted-by":"publisher","DOI":"10.3390\/bios12110922"},{"key":"ref123","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-44388-9"},{"key":"ref125","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15122671"},{"key":"ref127","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-08-102555-0.00007-8"},{"key":"ref129","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b09331"},{"key":"ref131","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27217232"},{"key":"ref133","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11050640"},{"key":"ref135","doi-asserted-by":"publisher","DOI":"10.1039\/D5NR90093J"},{"key":"ref137","doi-asserted-by":"publisher","DOI":"10.3390\/nu13113914"},{"key":"ref139","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13030326"},{"key":"ref141","doi-asserted-by":"publisher","DOI":"10.1002\/ddr.21545"},{"key":"ref143","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.0c05848"},{"key":"ref145","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.607692"},{"key":"ref147","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21249713"},{"key":"ref149","doi-asserted-by":"publisher","DOI":"10.3390\/ph14060535"},{"key":"ref151","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241713262"},{"key":"ref153","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1355335"},{"key":"ref155","doi-asserted-by":"publisher","DOI":"10.1007\/s40139-021-00223-3"},{"key":"ref157","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.115049"},{"key":"ref159","doi-asserted-by":"publisher","DOI":"10.2174\/1389200223666220627110049"},{"key":"ref161","doi-asserted-by":"publisher","DOI":"10.1080\/17425247.2021.1828339"},{"key":"ref163","doi-asserted-by":"publisher","DOI":"10.1039\/D4NR01423E"},{"key":"ref165","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-017-0450-0"},{"key":"ref167","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c11858"},{"key":"ref169","doi-asserted-by":"publisher","DOI":"10.4018\/979-8-3693-7728-4.ch010"},{"key":"ref171","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2020.119488"},{"key":"ref173","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13060840"},{"key":"ref175","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26237063"},{"key":"ref177","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2022.103108"},{"key":"ref179","doi-asserted-by":"publisher","DOI":"10.1039\/D1NR07882H"},{"key":"ref181","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.0c00567"}],"container-title":["Iranian Biomedical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ibj.pasteur.ac.ir\/article-1-4960-en.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ibj.pasteur.ac.ir\/article-1-4960-en.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T15:16:56Z","timestamp":1765379816000},"score":1,"resource":{"primary":{"URL":"https:\/\/ibj.pasteur.ac.ir\/article-1-4960-en.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,1]]},"references-count":91,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4,1]]}},"URL":"https:\/\/doi.org\/10.61882\/ibj.4960","relation":{},"ISSN":["2074-1847"],"issn-type":[{"value":"2074-1847","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,1]]}}}