{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:21:01Z","timestamp":1791591661468,"version":"4.3.4"},"reference-count":23,"publisher":"e-Century Publishing Corporation","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Clin Exp Pathol"],"DOI":"10.62347\/aehs8635","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T23:54:46Z","timestamp":1750809286000},"page":"258-266","source":"Crossref","is-referenced-by-count":4,"title":["Clinicopathologic characteristics and outcome of gastric-type endocervical adenocarcinoma: a single-center retrospective study"],"prefix":"10.62347","volume":"18","author":[{"given":"Hai-Mei","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"48694","published-online":{"date-parts":[[2025]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"154261","DOI":"10.1016\/j.prp.2022.154261","article-title":"Diagnostic accuracy of HIK1083 and MUC6 as immunohistochemical markers of endocervical gastric-type adenocarcinoma: a systematic review and meta-analysis","volume":"241","author":"Fulgione","year":"2023","unstructured":"Fulgione C, Raffone A, Travaglino A, Arciuolo D, Santoro A, Cianfrini F, Russo D, Varricchio S, Raimondo I, Inzani F, Mollo A, Guida M, Mascolo M and Zannoni GF. Diagnostic accuracy of HIK1083 and MUC6 as immunohistochemical markers of endocervical gastric-type adenocarcinoma: a systematic review and meta-analysis. Pathol Res Pract 2023; 241: 154261.","journal-title":"Pathol Res Pract"},{"key":"ref1","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.ygyno.2019.01.022","article-title":"Analysis of gastric-type mucinous carcinoma of the uterine cervix - an aggressive tumor with a poor prognosis: a multi-institutional study","volume":"153","author":"Nishio","year":"2019","unstructured":"Nishio S, Mikami Y, Tokunaga H, Yaegashi N, Satoh T, Saito M, Okamoto A, Kasamatsu T, Miyamoto T, Shiozawa T, Yoshioka Y, Mandai M, Kojima A, Takehara K, Kaneki E, Kobayashi H, Kaku T, Ushijima K and Kamura T. Analysis of gastric-type mucinous carcinoma of the uterine cervix - an aggressive tumor with a poor prognosis: a multi-institutional study. Gynecol Oncol 2019; 153: 13-19.","journal-title":"Gynecol Oncol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1097\/01.pas.0000213434.91868.b0","article-title":"Gastric morphology and immunophenotype predict poor outcome in mucinous adenocarcinoma of the uterine cervix","volume":"31","author":"Kojima","year":"2007","unstructured":"Kojima A, Mikami Y, Sudo T, Yamaguchi S, Kusanagi Y, Ito M and Nishimura R. Gastric morphology and immunophenotype predict poor outcome in mucinous adenocarcinoma of the uterine cervix. Am J Surg Pathol 2007; 31: 664-672.","journal-title":"Am J Surg Pathol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1097\/PAS.0000000000000986","article-title":"International endocervical adenocarcinoma criteria and classification (IECC): a new pathogenetic classification for invasive adenocarcinomas of the endocervix","volume":"42","author":"Stolnicu","year":"2018","unstructured":"Stolnicu S, Barsan I, Hoang L, Patel P, Terinte C, Pesci A, Aviel-Ronen S, Kiyokawa T, Alvarado-Cabrero I, Pike MC, Oliva E, Park KJ and Soslow RA. International endocervical adenocarcinoma criteria and classification (IECC): a new pathogenetic classification for invasive adenocarcinomas of the endocervix. Am J Surg Pathol 2018; 42: 214-226.","journal-title":"Am J Surg Pathol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1002\/ijgo.12749","article-title":"Revised FIGO staging for carcinoma of the cervix uteri","volume":"145","author":"Bhatla","year":"2019","unstructured":"Bhatla N, Berek JS, Cuello Fredes M, Denny LA, Grenman S, Karunaratne K, Kehoe ST, Konishi I, Olawaiye AB, Prat J, Sankaranarayanan R, Brierley J, Mutch D, Querleu D, Cibula D, Quinn M, Botha H, Sigurd L, Rice L, Ryu HS, Ngan H, M&#xE4;enp&#xE4;&#xE4; J, Andrijono A, Purwoto G, Maheshwari A, Bafna UD, Plante M and Natarajan J. Revised FIGO staging for carcinoma of the cervix uteri. Int J Gynaecol Obstet 2019; 145: 129-135.","journal-title":"Int J Gynaecol Obstet"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1097\/PAS.0000000000000855","article-title":"HPV-negative gastric type adenocarcinoma in situ of the cervix: a spectrum of rare lesions exhibiting gastric and intestinal differentiation","volume":"41","author":"Talia","year":"2017","unstructured":"Talia KL, Stewart CJR, Howitt BE, Nucci MR and McCluggage WG. HPV-negative gastric type adenocarcinoma in situ of the cervix: a spectrum of rare lesions exhibiting gastric and intestinal differentiation. Am J Surg Pathol 2017; 41: 1023-1033.","journal-title":"Am J Surg Pathol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1038\/sj.bjc.6601157","article-title":"Incidence and survival rate of women with cervical cancer in the greater amsterdam area","volume":"89","author":"Bulk","year":"2003","unstructured":"Bulk S, Visser O, Rozendaal L, Verheijen RH and Meijer CJ. Incidence and survival rate of women with cervical cancer in the greater amsterdam area. Br J Cancer 2003; 89: 834-839.","journal-title":"Br J Cancer"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1807","DOI":"10.1097\/PAS.0b013e3181883722","article-title":"Is lobular endocervical glandular hyperplasia a cancerous precursor of minimal deviation adenocarcinoma?: a comparative molecular-genetic and immunohistochemical study","volume":"32","author":"Kawauchi","year":"2008","unstructured":"Kawauchi S, Kusuda T, Liu XP, Suehiro Y, Kaku T, Mikami Y, Takeshita M, Nakao M, Chochi Y and Sasaki K. Is lobular endocervical glandular hyperplasia a cancerous precursor of minimal deviation adenocarcinoma?: a comparative molecular-genetic and immunohistochemical study. Am J surg PathoI 2008; 32: 1807-1815.","journal-title":"Am J surg PathoI"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1097\/IGC.0b013e31821f746c","article-title":"Preoperative differential diagnosis of minimal deviation adenocarcinoma and lobular endocervical glandular hyperplasia of the uterine cervix: a multicenter study of clinicopathology and magnetic resonance imaging findings","volume":"21","author":"Takatsu","year":"2011","unstructured":"Takatsu A, Shiozawa T, Miyamoto T, Kurosawa K, Kashima H, Yamada T, Kaku T, Mikami Y, Kiyokawa T, Tsuda H, Ishii K, Togashi K, Koyama T, Fujinaga Y, Kadoya M, Hashi A, Susumu N and Konishi I. Preoperative differential diagnosis of minimal deviation adenocarcinoma and lobular endocervical glandular hyperplasia of the uterine cervix: a multicenter study of clinicopathology and magnetic resonance imaging findings. Int J Gynecol Cancer 2011; 21: 1287-1296.","journal-title":"Int J Gynecol Cancer"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1111\/jog.14602","article-title":"Usefulness of the &#x2018;cosmos pattern&#x2019; for differentiating between cervical gastric-type mucin-positive lesions and other benign cervical cystic lesions in magnetic resonance images","volume":"47","author":"Ohya","year":"2021","unstructured":"Ohya A, Kobara H, Miyamoto T, Komatsu M, Shiozawa T and Fujinaga Y. Usefulness of the &#x2018;cosmos pattern&#x2019; for differentiating between cervical gastric-type mucin-positive lesions and other benign cervical cystic lesions in magnetic resonance images. J Obstet Gynaecol Res 2021; 47: 745-756.","journal-title":"J Obstet Gynaecol Res"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"945984","DOI":"10.3389\/fsurg.2022.945984","article-title":"Gastric-type mucinous carcinoma with an abnormal increase of CA199: a case report and literature review","volume":"9","author":"Qian","year":"2022","unstructured":"Qian XQ, Wang FF, Liang Y, Chen LL and Wan XY. Gastric-type mucinous carcinoma with an abnormal increase of CA199: a case report and literature review. Front Surg 2022; 9: 945984.","journal-title":"Front Surg"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s00428-018-2469-z","article-title":"Trefoil factor family 2 protein: a potential immunohistochemical marker for aiding diagnosis of lobular endocervical glandular hyperplasia and gastric-type adenocarcinoma of the uterine cervix","volume":"474","author":"Asaka","year":"2019","unstructured":"Asaka S, Nakajima T, Momose M, Miyamoto T, Uehara T and Ota H. Trefoil factor family 2 protein: a potential immunohistochemical marker for aiding diagnosis of lobular endocervical glandular hyperplasia and gastric-type adenocarcinoma of the uterine cervix. Virchows Arch 2019; 474: 79-86.","journal-title":"Virchows Arch"},{"key":"ref12","unstructured":"Peng WX, Kure S, Ishino K, Kurose K, Yoneyama K, Wada R and Naito Z. P16-positive continuous minimal deviation adenocarcinoma and gastric type adenocarcinoma in a patient with Peutz-Jeghers syndrome. Int J Clin Exp Pathol 2015; 8: 5877-5882."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1097\/PAS.0000000000001090","article-title":"Diagnostic algorithmic proposal based on comprehensive Immunohistochemical evaluation of 297 invasive Endocervical adenocarcinomas","volume":"42","author":"Stolnicu","year":"2018","unstructured":"Stolnicu S, Barsan I, Hoang L, Patel P, Chiriboga L, Terinte C, Pesci A, Aviel-Ronen S, Kiyokawa T, Alvarado-Cabrero I, Pike MC, Oliva E, Park KJ and Soslow RA. Diagnostic algorithmic proposal based on comprehensive Immunohistochemical evaluation of 297 invasive Endocervical adenocarcinomas. Am J Surg Pathol 2018; 42: 989-1000.","journal-title":"Am J Surg Pathol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1186\/s13000-019-0852-y","article-title":"Primary endocervical gastric-type adenocarcinoma: a clinicopathologic and immunohistochemical analysis of 23 cases","volume":"14","author":"Lu","year":"2019","unstructured":"Lu S, Shen D, Zhao Y, Kang N and Wang X. Primary endocervical gastric-type adenocarcinoma: a clinicopathologic and immunohistochemical analysis of 23 cases. Diagn Pathol 2019; 14: 72-78.","journal-title":"Diagn Pathol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1097\/PAS.0000000000000578","article-title":"A detailed immunohistochemical analysis of a large series of cervical and vaginal gastric-type adenocarcinomas","volume":"40","author":"Carleton","year":"2016","unstructured":"Carleton C, Hoang L, Sah S, Kiyokawa T, Karamurzin YS, Talia KL, Park KJ and McCluggage WG. A detailed immunohistochemical analysis of a large series of cervical and vaginal gastric-type adenocarcinomas. Am J Surg Pathol 2016; 40: 636-644.","journal-title":"Am J Surg Pathol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1111\/j.1365-2559.2005.02057.x","article-title":"Immunophenotypic alteration of the stromal component in minimal deviation adenocarcinoma (&#x2018;adenoma malignum&#x2019;) and endocervical glandular hyperplasia: a study using oestrogen receptor and alpha-smooth muscle actin double immunostaining","volume":"46","author":"Mikami","year":"2005","unstructured":"Mikami Y, Kiyokawa T, Moriya T and Sasano H. Immunophenotypic alteration of the stromal component in minimal deviation adenocarcinoma (&#x2018;adenoma malignum&#x2019;) and endocervical glandular hyperplasia: a study using oestrogen receptor and alpha-smooth muscle actin double immunostaining. Histopathology 2005; 46: 130-136.","journal-title":"Histopathology"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1823","DOI":"10.1038\/s41379-019-0305-x","article-title":"Molecular characterization of gastric-type endocervical adenocarcinoma using next-generation sequencing","volume":"32","author":"Garg","year":"2019","unstructured":"Garg S, Nagaria TS, Clarke B, Freedman O, Khan Z, Schwock J, Bernardini MQ, Oza AM, Han K, Smith AC, Stockley TL and Rouzbahman M. Molecular characterization of gastric-type endocervical adenocarcinoma using next-generation sequencing. Mod Pathol 2019; 32: 1823-1833.","journal-title":"Mod Pathol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.path.2016.01.006","article-title":"Peutz-Jeghers syndrome: pathobiology, pathologic manifestations, and suggestions for recommending genetic testing in pathology reports","volume":"9","author":"Meserve","year":"2016","unstructured":"Meserve EE and Nucci MR. Peutz-Jeghers syndrome: pathobiology, pathologic manifestations, and suggestions for recommending genetic testing in pathology reports. Surg Pathol Clin 2016; 9: 243-268.","journal-title":"Surg Pathol Clin"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1136\/ijgc-2021-002997","article-title":"Gastric-type adenocarcinoma of the cervix in patients with Peutz-Jeghers syndrome: a systematic review of the literature with proposed screening guidelines","volume":"32","author":"Gordhandas","year":"2022","unstructured":"Gordhandas SB, Kahn R, Sassine D, Aviki EM, Baltich Nelson B, Catchings A, Liu YL, Lakhman Y, Abu-Rustum NR, Park KJ and Mueller JJ. Gastric-type adenocarcinoma of the cervix in patients with Peutz-Jeghers syndrome: a systematic review of the literature with proposed screening guidelines. Int J Gynecol Cancer 2022; 32: 79-88.","journal-title":"Int J Gynecol Cancer"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1007\/s00795-018-0202-2","article-title":"Mucinous adenocarcinoma, gastric type of the uterine cervix: clinical features and HER2 amplification","volume":"52","author":"Nakamura","year":"2019","unstructured":"Nakamura A, Yamaguchi K, Minamiguchi S, Murakami R, Abiko K, Hamanishi J, Kondoh E, Baba T, Mandai M and Matsumura N. Mucinous adenocarcinoma, gastric type of the uterine cervix: clinical features and HER2 amplification. Med Mol Morphol 2019; 52: 52-59.","journal-title":"Med Mol Morphol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"100148","DOI":"10.1016\/j.modpat.2023.100148","article-title":"Assessment of HER2 in gastric-type endocervical adenocarcinoma and its prognostic significance","volume":"36","author":"Wang","year":"2023","unstructured":"Wang S, Zhou X, Niu S, Chen L, Zhang H, Chen H and Zhou F. Assessment of HER2 in gastric-type endocervical adenocarcinoma and its prognostic significance. Mod Pathol 2023; 36: 100148.","journal-title":"Mod Pathol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/j.ygyno.2022.10.003","article-title":"Gastric-type adenocarcinoma of the cervix: clinical outcomes and genomic drivers","volume":"167","author":"Ehmann","year":"2022","unstructured":"Ehmann S, Sassine D, Straubhar AM, Praiss AM, Aghajanian C, Alektiar KM, Broach V, Cadoo KA, Jewell EL, Boroujeni AM, Kyi C, Leitao MM, Mueller JJ, Murali R, Bhaloo SI, O&#x2019;Cearbhaill RE, Park KJ, Sonoda Y, Weigelt B, Zamarin D, Abu-Rustum N and Friedman CF. Gastric-type adenocarcinoma of the cervix: clinical outcomes and genomic drivers. Gynecol Oncol 2022; 167: 458-466.","journal-title":"Gynecol Oncol"}],"container-title":["International Journal of Clinical and Experimental Pathology"],"original-title":[],"link":[{"URL":"https:\/\/e-century.us\/files\/ijcep\/18\/6\/ijcep0162987.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T01:57:11Z","timestamp":1766023031000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-century.us\/files\/ijcep\/18\/6\/ijcep0162987.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":23,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.62347\/aehs8635","relation":{},"ISSN":["1936-2625"],"issn-type":[{"value":"1936-2625","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}