{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T05:23:57Z","timestamp":1769232237234,"version":"3.49.0"},"reference-count":26,"publisher":"e-Century Publishing Corporation","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Transl Res"],"DOI":"10.62347\/idst8640","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T08:57:12Z","timestamp":1761728232000},"page":"7828-7837","source":"Crossref","is-referenced-by-count":0,"title":["Reversal effect of sugammadex sodium on rocuronium-induced neuromuscular blockade in patients undergoing painless tracheoscopy"],"prefix":"10.62347","volume":"17","author":[{"given":"Xia","family":"Hu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"48694","published-online":{"date-parts":[[2025]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Zhou P, Fu D, Luo C, Dai RP and Luo RY. Unveiling the impact of airways: a comparative analysis of oropharyngeal and nasopharyngeal airways in painless fiberoptic bronchoscopy. Heliyon 2024; 10: e35053.","DOI":"10.1016\/j.heliyon.2024.e35053"},{"key":"ref1","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1097\/ALN.0000000000004011","article-title":"Mediastinal masses, anesthetic interventions, and airway compression in adults: a prospective observational study","volume":"136","author":"Hartigan","year":"2022","unstructured":"Hartigan PM, Karamnov S, Gill RR, Ng JM, Yacoubian S, Tsukada H, Swanson J, Barlow J, McMurry TL and Blank RS. Mediastinal masses, anesthetic interventions, and airway compression in adults: a prospective observational study. Anesthesiology 2022; 136: 104-114.","journal-title":"Anesthesiology"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"15","DOI":"10.4103\/joacp.joacp_139_22","article-title":"Coadministration of intravenous calcium along with neostigmine for rapid neuromuscular blockade recovery: a systematic review and meta-analysis","volume":"40","author":"Khanna","year":"2024","unstructured":"Khanna P, Das A and Sarkar S. Coadministration of intravenous calcium along with neostigmine for rapid neuromuscular blockade recovery: a systematic review and meta-analysis. J Anaesthesiol Clin Pharmacol 2024; 40: 15-21.","journal-title":"J Anaesthesiol Clin Pharmacol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1097\/ACO.0000000000000466","article-title":"Anesthetic consideration for neuromuscular diseases","volume":"30","author":"Katz","year":"2017","unstructured":"Katz JA and Murphy GS. Anesthetic consideration for neuromuscular diseases. Curr Opin Anaesthesiol 2017; 30: 435-440.","journal-title":"Curr Opin Anaesthesiol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"4819910","DOI":"10.1155\/2022\/4819910","article-title":"Antinociceptive effects and interaction mechanisms of intrathecal pentazocine and neostigmine in two different pain models in rats","volume":"2022","author":"Huang","year":"2022","unstructured":"Huang H, Bai X, Zhang K, Guo J, Wu S and Ouyang H. Antinociceptive effects and interaction mechanisms of intrathecal pentazocine and neostigmine in two different pain models in rats. Pain Res Manag 2022; 2022: 4819910.","journal-title":"Pain Res Manag"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1007\/s40266-022-00969-4","article-title":"Optimizing reversal of neuromuscular block in older adults: sugammadex or neostigmine","volume":"39","author":"Togioka","year":"2022","unstructured":"Togioka BM and Schenning KJ. Optimizing reversal of neuromuscular block in older adults: sugammadex or neostigmine. Drugs Aging 2022; 39: 749-761.","journal-title":"Drugs Aging"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Shrestha IK, Chalise R, Poudel S, Regmi A, Ghimire A, Khadka B and Khanal K. Neostigmine and atropine as a treatment for postdural puncture headache after spinal anesthesia in cesarean section: a case report. Clin Case Rep 2023; 11: e8132.","DOI":"10.1002\/ccr3.8132"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Niu L, Wang Y, Yao C, Sun Y, Yao S and Lin Y. Efficacy and safety of neuromuscular blockade in overweight patients undergoing nasopharyngeal surgery. Med Sci Monit 2020; 26: e926452.","DOI":"10.12659\/MSM.926452"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"114072","DOI":"10.1016\/j.jpba.2021.114072","article-title":"Isolation, structural characterization and quality control strategy of an unknown process-related impurity in sugammadex sodium","volume":"200","author":"Zhuang","year":"2021","unstructured":"Zhuang T, Chen Y, Xu J, Qi Z, Ye J, Xu C, Du W, Liu B and Zhang G. Isolation, structural characterization and quality control strategy of an unknown process-related impurity in sugammadex sodium. J Pharm Biomed Anal 2021; 200: 114072.","journal-title":"J Pharm Biomed Anal"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"697395","DOI":"10.3389\/fmed.2021.697395","article-title":"Efficiency and safety of the selective relaxant binding agent adamgammadex sodium for reversing rocuronium-induced deep neuromuscular block: a single-center, open-label, dose-finding, and phase IIa study","volume":"8","author":"Zhao","year":"2021","unstructured":"Zhao Y, Chen S, Huai X, Yu Z, Qi Y, Qing J, Yu W and Su D. Efficiency and safety of the selective relaxant binding agent adamgammadex sodium for reversing rocuronium-induced deep neuromuscular block: a single-center, open-label, dose-finding, and phase IIa study. Front Med (Lausanne) 2021; 8: 697395.","journal-title":"Front Med (Lausanne)"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1080\/14740338.2019.1649393","article-title":"Safety of sugammadex for reversal of neuromuscular block","volume":"18","author":"Honing","year":"2019","unstructured":"Honing G, Martini CH, Bom A, van Velzen M, Niesters M, Aarts L, Dahan A and Boon M. Safety of sugammadex for reversal of neuromuscular block. Expert Opin Drug Saf 2019; 18: 883-891.","journal-title":"Expert Opin Drug Saf"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"114419","DOI":"10.1016\/j.jpba.2021.114419","article-title":"A study on structural characterization of potential impurities of Sugammadex sodium using LC\/ESI\/QTOF\/MS\/MS and NMR","volume":"207","author":"Mohanraj","year":"2022","unstructured":"Mohanraj SKP, Tulasi R, Subramanian VC, Dandu BSR, Guvvala V and Kota SR. A study on structural characterization of potential impurities of Sugammadex sodium using LC\/ESI\/QTOF\/MS\/MS and NMR. J Pharm Biomed Anal 2022; 207: 114419.","journal-title":"J Pharm Biomed Anal"},{"key":"ref12","unstructured":"Welliver M and Cheek D. An update on sugammadex sodium. AANA J 2009; 77: 219-228."},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"Lu L, Chen X, Li S and Cen Y. Comparison of effects of sugammadex and neostigmine on postoperative neuromuscular blockade recovery in patients with interstitial lung diseases undergoing transbronchial cryobiopsy: a randomized trial. Med Sci Monit 2024; 30: e942773.","DOI":"10.12659\/MSM.942773"},{"key":"ref14","unstructured":"Schepens T and Cammu G. Neuromuscular blockade: what was, is and will be. Acta Anaesthesiol Belg 2014; 65: 151-159."},{"key":"ref15","doi-asserted-by":"publisher","first-page":"476","DOI":"10.4097\/kja.d.17.00011","article-title":"Effects of adenosine receptor agonist on the rocuroniuminduced neuromuscular block and sugammadex-induced recovery","volume":"71","author":"Kim","year":"2018","unstructured":"Kim YB, Lee S, Choi HR, In J, Chang YJ, Kim HJ, Ro YJ and Yang HS. Effects of adenosine receptor agonist on the rocuroniuminduced neuromuscular block and sugammadex-induced recovery. Korean J Anesthesiol 2018; 71: 476-482.","journal-title":"Korean J Anesthesiol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"454","DOI":"10.4183\/aeb.2019.454","article-title":"Thyroid surgery, ionm and sugammadex sodium relationships: benefits in sugammadex sodium use for ionm","volume":"15","author":"Donmez","year":"2019","unstructured":"Donmez T, Erdem VM, Sunamak O and Ozcevik H. Thyroid surgery, ionm and sugammadex sodium relationships: benefits in sugammadex sodium use for ionm. Acta Endocrinol (Buchar) 2019; 15: 454-459.","journal-title":"Acta Endocrinol (Buchar)"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.jclinane.2019.02.014","article-title":"Influence of reversal of neuromuscular blockade with sugammadex or neostigmine on postoperative quality of recovery following a single bolus dose of rocuronium: a prospective, randomized, double-blinded, controlled study","volume":"57","author":"Kim","year":"2019","unstructured":"Kim NY, Koh JC, Lee KY, Kim SS, Hong JH, Nam HJ and Bai SJ. Influence of reversal of neuromuscular blockade with sugammadex or neostigmine on postoperative quality of recovery following a single bolus dose of rocuronium: a prospective, randomized, double-blinded, controlled study. J Clin Anesth 2019; 57: 97-102.","journal-title":"J Clin Anesth"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"14955","DOI":"10.1038\/s41598-022-18917-y","article-title":"Predictive study of pharmacological reversal for residual neuromuscular blockade and postoperative pulmonary complications: a prospective, observational, cohort study","volume":"12","author":"Aragon-Benedi C","year":"2022","unstructured":"Aragon-Benedi C, Pascual-Bellosta A, Ortega-Lucea S, Visiedo-Sanchez S and Martinez-Ubieto J; Research Group in Anaesthesia, Resuscitation, and Perioperative Medicine of Institute for Health Research Aragón (ISS Aragón). Predictive study of pharmacological reversal for residual neuromuscular blockade and postoperative pulmonary complications: a prospective, observational, cohort study. Sci Rep 2022; 12: 14955.","journal-title":"Sci Rep"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1097\/EJA.0000000000000823","article-title":"Duration of the action of rocuronium in patients with BMI of less than 25: an observational study","volume":"35","author":"Takahata","year":"2018","unstructured":"Takahata O, Takahoko KI, Sasakawa T, Inagaki Y, Takahoko H and Kunisawa T. Duration of the action of rocuronium in patients with BMI of less than 25: an observational study. Eur J Anaesthesiol 2018; 35: 863-866.","journal-title":"Eur J Anaesthesiol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1007\/s40801-020-00200-z","article-title":"Knowledge and understanding of the safety and efficacy aspects of BRIDION((R)) among canadian anesthesiologists","volume":"7","author":"Stemhagen","year":"2020","unstructured":"Stemhagen A, Bhangu P, Zhong W, Julian M, Deutsch G and Koro C. Knowledge and understanding of the safety and efficacy aspects of BRIDION((R)) among canadian anesthesiologists. Drugs Real World Outcomes 2020; 7: 251-256.","journal-title":"Drugs Real World Outcomes"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"31239","DOI":"10.1038\/s41598-024-82582-6","article-title":"The effect of toluene sulfonic acid remimazolam on postoperative delirium in elderly patients undergoing painless bronchoscopy","volume":"14","author":"Shi","year":"2024","unstructured":"Shi Y, Zhang L, Diao Y and Zhao M. The effect of toluene sulfonic acid remimazolam on postoperative delirium in elderly patients undergoing painless bronchoscopy. Sci Rep 2024; 14: 31239.","journal-title":"Sci Rep"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.11124\/JBISRIR-2017-003997","article-title":"Sugammadex versus neostigmine for postoperative nausea and vomiting in adult patients undergoing laparoscopic surgery paralyzed with rocuronium bromide: a systematic review protocol","volume":"17","author":"Freundlich","year":"2019","unstructured":"Freundlich A, Badeaux J and Adorno M. Sugammadex versus neostigmine for postoperative nausea and vomiting in adult patients undergoing laparoscopic surgery paralyzed with rocuronium bromide: a systematic review protocol. JBI Database System Rev Implement Rep 2019; 17: 2187-2192.","journal-title":"JBI Database System Rev Implement Rep"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"Suzuki K, Sunaga H, Yamakawa K, Suga Y, Kondo I, Tsubokawa T and Uezono S. Intravenous infusion of rocuronium bromide prolongs emergence from propofol anesthesia in rats. PLoS One 2021; 16: e0246858.","DOI":"10.1371\/journal.pone.0246858"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1399475","DOI":"10.3389\/fmed.2024.1399475","article-title":"Feasibility of calculating rocuronium dosage by skeletal muscle weight in patients with obesity","volume":"11","author":"Hu","year":"2024","unstructured":"Hu Z, Li B, Li Z, Liu Z and Liu S. Feasibility of calculating rocuronium dosage by skeletal muscle weight in patients with obesity. Front Med (Lausanne) 2024; 11: 1399475.","journal-title":"Front Med (Lausanne)"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"803","DOI":"10.12659\/MSM.897608","article-title":"Effects of sugammadex and neostigmine on renal biomarkers","volume":"22","author":"Isik","year":"2016","unstructured":"Isik Y, Palabiyik O, Cegin BM, Goktas U and Kati I. Effects of sugammadex and neostigmine on renal biomarkers. Med Sci Monit 2016; 22: 803-809.","journal-title":"Med Sci Monit"}],"container-title":["American Journal of Translational Research"],"original-title":[],"link":[{"URL":"https:\/\/e-century.us\/files\/ajtr\/17\/10\/ajtr0166457.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T01:45:26Z","timestamp":1769132726000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-century.us\/files\/ajtr\/17\/10\/ajtr0166457.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":26,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.62347\/idst8640","relation":{},"ISSN":["1943-8141"],"issn-type":[{"value":"1943-8141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}