{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T02:01:31Z","timestamp":1766023291049,"version":"3.48.0"},"reference-count":31,"publisher":"e-Century Publishing Corporation","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Transl Res"],"DOI":"10.62347\/jvgt3596","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T03:47:37Z","timestamp":1754624857000},"page":"5625-5640","source":"Crossref","is-referenced-by-count":0,"title":["Development of a carbon nanoparticle-guided nomogram for predicting lateral cervical lymph node metastasis in clinically node-negative papillary thyroid carcinoma"],"prefix":"10.62347","volume":"17","author":[{"given":"Hui","family":"Qu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"48694","published-online":{"date-parts":[[2025]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"1495617","DOI":"10.3389\/fonc.2025.1495617","article-title":"Ferroptosis in thyroid cancer: mechanisms, current status, and treatment","volume":"15","author":"Tian","year":"2025","unstructured":"Tian W, Su X, Hu C, Chen D and Li P. Ferroptosis in thyroid cancer: mechanisms, current status, and treatment. Front Oncol 2025; 15: 1495617.","journal-title":"Front Oncol"},{"key":"ref1","doi-asserted-by":"publisher","first-page":"179","DOI":"10.3390\/biomedicines10010179","article-title":"Predictive factors for skip lymph node metastasis and their implication on recurrence in papillary thyroid carcinoma","volume":"10","author":"Ryu","year":"2022","unstructured":"Ryu YJ, Kwon SY, Lim SY, Na YM and Park MH. Predictive factors for skip lymph node metastasis and their implication on recurrence in papillary thyroid carcinoma. Biomedicines 2022; 10: 179.","journal-title":"Biomedicines"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"9542","DOI":"10.1038\/s41598-025-92295-z","article-title":"Predictive risk-scoring model for lateral lymph node metastasis in papillary thyroid carcinoma","volume":"15","author":"Guo","year":"2025","unstructured":"Guo Y, Liu Y, Teng W, Pan Y, Zhang L, Feng D, Wu J, Ma W, Wang J, Xu J, Zheng C, Zhu X, Tan Z and Jiang L. Predictive risk-scoring model for lateral lymph node metastasis in papillary thyroid carcinoma. Sci Rep 2025; 15: 9542.","journal-title":"Sci Rep"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1288527","DOI":"10.3389\/fendo.2023.1288527","article-title":"Risk factors for central lymph node metastasis in patients with papillary thyroid carcinoma: a retrospective study","volume":"14","author":"Du","year":"2023","unstructured":"Du J, Yang Q, Sun Y, Shi P, Xu H, Chen X, Dong T, Shi W, Wang Y, Song Z, Shang X and Tian X. Risk factors for central lymph node metastasis in patients with papillary thyroid carcinoma: a retrospective study. Front Endocrinol (Lausanne) 2023; 14: 1288527.","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.anl.2023.10.003","article-title":"Central node dissection from the perspective of lateral neck node metastasis in papillary thyroid carcinoma","volume":"51","author":"Taniuchi","year":"2024","unstructured":"Taniuchi M, Kawata R, Terada T, Higashino M, Aihara T and Jinnin T. Central node dissection from the perspective of lateral neck node metastasis in papillary thyroid carcinoma. Auris Nasus Larynx 2024; 51: 266-270.","journal-title":"Auris Nasus Larynx"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Song WJ, Um IC, Kwon SR, Lee JH, Lim HW, Jeong YU, Chung SM, Moon JS, Yoon JS, Won KC and Lee HW. Predictive factors of lymph node metastasis in papillary thyroid cancer. PLoS One 2023; 18: e0294594.","DOI":"10.1371\/journal.pone.0294594"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1186\/s12893-022-01678-w","article-title":"Analysis of factors influencing cervical lymph node metastasis of papillary thyroid carcinoma at each lateral level","volume":"22","author":"Liu","year":"2022","unstructured":"Liu WQ, Yang JY, Wang XH, Cai W and Li F. Analysis of factors influencing cervical lymph node metastasis of papillary thyroid carcinoma at each lateral level. BMC Surg 2022; 22: 228.","journal-title":"BMC Surg"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"11795549241233692","DOI":"10.1177\/11795549241233692","article-title":"Surgical complications in papillary thyroid cancer patients with cervical lymph node metastases","volume":"18","author":"MC","year":"2024","unstructured":"Pham MC, Nguyen T and Nguyen HP. Surgical complications in papillary thyroid cancer patients with cervical lymph node metastases. Clin Med Insights Oncol 2024; 18: 11795549241233692.","journal-title":"Clin Med Insights Oncol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1400","DOI":"10.21037\/gs-24-164","article-title":"Correlation between body mass index and lymph node metastasis in papillary thyroid carcinoma: a retrospective clinical study","volume":"13","author":"Ding","year":"2024","unstructured":"Ding H, Xu F, Guan W and Sang J. Correlation between body mass index and lymph node metastasis in papillary thyroid carcinoma: a retrospective clinical study. Gland Surg 2024; 13: 1400-1407.","journal-title":"Gland Surg"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"Zhang W, Shu Y, Ni D, Wan Z and Yang S. Comparison of two suspension injection tracers of nano activated carbon and methylene blue in mapping and tracing of sentinel lymph nodes of patients with endometrial cancer. Pak J Med Sci 2022; 38: 1601-1605.","DOI":"10.12669\/pjms.38.6.5714"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"Lim JH, Han A, Cho SJ, Hahn S and Kim SG. Nomogram prediction for gastric cancer development. Clin Transl Gastroenterol 2025; 16: e00833.","DOI":"10.14309\/ctg.0000000000000833"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1001\/jamaoto.2022.3360","article-title":"American thyroid association guidelines and national trends in management of papillary thyroid carcinoma","volume":"148","author":"Gordon","year":"2022","unstructured":"Gordon AJ, Dublin JC, Patel E, Papazian M, Chow MS, Persky MJ, Jacobson AS, Patel KN, Suh I, Morris LGT and Givi B. American thyroid association guidelines and national trends in management of papillary thyroid carcinoma. JAMA Otolaryngol Head Neck Surg 2022; 148: 1156-1163.","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.12669\/pjms.38.7.5826","article-title":"Endoscopic-assisted lateral neck dissection and open lateral neck dissection in the treatment of lateral neck lymph node metastasis in papillary thyroid carcinoma: a comparison of therapeutic effect","volume":"38","author":"Ma","year":"2022","unstructured":"Ma T, Zhang S, Huang D, Zhang G, Chen B and Zhang N. Endoscopic-assisted lateral neck dissection and open lateral neck dissection in the treatment of lateral neck lymph node metastasis in papillary thyroid carcinoma: a comparison of therapeutic effect. Pak J Med Sci 2022; 38: 1905-1910.","journal-title":"Pak J Med Sci"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"591015","DOI":"10.3389\/fendo.2021.591015","article-title":"Diagnostic model incorporating clinicopathological characteristics of delphian lymph node metastasis risk profiles in papillary thyroid cancer","volume":"12","author":"Li","year":"2021","unstructured":"Li X, Duan Y, Liu D, Liu H, Zhou M, Yue K, Shuai Y, Wang Y, Ji C, Jing C, Wu Y and Wang X. Diagnostic model incorporating clinicopathological characteristics of delphian lymph node metastasis risk profiles in papillary thyroid cancer. Front Endocrinol (Lausanne) 2021; 12: 591015.","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"Luo X, Zhou Y, Rao K, Xiang J, Ning S, Zhu D, Li G and Chen H. Biomimetic cascade nanozyme catalytic system for the treatment of lymph node metastasis in gastric cancer. Small 2025; 21: e2411576.","DOI":"10.1002\/smll.202411576"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"716728","DOI":"10.3389\/fendo.2021.716728","article-title":"Risk factors and a prediction model of lateral lymph node metastasis in CN0 papillary thyroid carcinoma patients with 1-2 central lymph node metastases","volume":"12","author":"Wang","year":"2021","unstructured":"Wang Y, Deng C, Shu X, Yu P, Wang H, Su X and Tan J. Risk factors and a prediction model of lateral lymph node metastasis in CN0 papillary thyroid carcinoma patients with 1-2 central lymph node metastases. Front Endocrinol (Lausanne) 2021; 12: 716728.","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"643416","DOI":"10.3389\/fonc.2021.643416","article-title":"Value of pyruvate carboxylase in thyroid fine-needle aspiration wash-out fluid for predicting papillary thyroid cancer lymph node metastasis","volume":"11","author":"Liu","year":"2021","unstructured":"Liu C, Zhang L, Liu Y, Zhao Q, Pan Y and Zhang Y. Value of pyruvate carboxylase in thyroid fine-needle aspiration wash-out fluid for predicting papillary thyroid cancer lymph node metastasis. Front Oncol 2021; 11: 643416.","journal-title":"Front Oncol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"9351911","DOI":"10.1155\/2022\/9351911","article-title":"Prediction of cervical lymph nodes metastasis in Papillary Thyroid Carcinoma (PTC) Using Nodal Staging Score (NSS)","volume":"2022","author":"Zhang","year":"2022","unstructured":"Zhang J, Jia G, Su Y, Zhang Z, Xiong H, Xu Q and Meng S. Prediction of cervical lymph nodes metastasis in Papillary Thyroid Carcinoma (PTC) Using Nodal Staging Score (NSS). J Oncol 2022; 2022: 9351911.","journal-title":"J Oncol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"307","DOI":"10.3390\/curroncol31010020","article-title":"Review on lymph node metastases, sentinel lymph node biopsy, and lymphadenectomy in sarcoma","volume":"31","author":"Chmiel","year":"2024","unstructured":"Chmiel P, Krotewicz M, Szumera-Cie&#x107;kiewicz A, Bartnik E, Czarnecka AM and Rutkowski P. Review on lymph node metastases, sentinel lymph node biopsy, and lymphadenectomy in sarcoma. Curr Oncol 2024; 31: 307-323.","journal-title":"Curr Oncol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1186\/s12885-024-12004-3","article-title":"Development of a nomogram for prediction of central lymph node metastasis of papillary thyroid microcarcinoma","volume":"24","author":"Qiu","year":"2024","unstructured":"Qiu P, Guo Q, Pan K and Lin J. Development of a nomogram for prediction of central lymph node metastasis of papillary thyroid microcarcinoma. BMC Cancer 2024; 24: 235.","journal-title":"BMC Cancer"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"Shen W, Pan XJ and Li QH. Utility and significance of clinical risk factor scoring model in predicting central compartment lymph node metastasis (CLNM) in patients with papillary thyroid cancer (PTC). Pak J Med Sci 2022; 38: 214-218.","DOI":"10.12669\/pjms.38.1.4450"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1349388","DOI":"10.3389\/fonc.2024.1349388","article-title":"Multi-modal ultrasound multistage classification of PTC cervical lymph node metastasis via DualSwinThyroid","volume":"14","author":"Liu","year":"2024","unstructured":"Liu Q, Li Y, Hao Y, Fan W, Liu J, Li T and Liu L. Multi-modal ultrasound multistage classification of PTC cervical lymph node metastasis via DualSwinThyroid. Front Oncol 2024; 14: 1349388.","journal-title":"Front Oncol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1002\/kjm2.12410","article-title":"Metastasis of pulmonary adenocarcinoma to the thyroid closely mimics papillary thyroid carcinoma","volume":"37","author":"CL","year":"2021","unstructured":"Tu CL and Lin CH. Metastasis of pulmonary adenocarcinoma to the thyroid closely mimics papillary thyroid carcinoma. Kaohsiung J Med Sci 2021; 37: 831-832.","journal-title":"Kaohsiung J Med Sci"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"3560","DOI":"10.1038\/s41467-024-47926-w","article-title":"An individualized protein-based prognostic model to stratify pediatric patients with papillary thyroid carcinoma","volume":"15","author":"Wang","year":"2024","unstructured":"Wang Z, Wang H, Zhou Y, Li L, Lyu M, Wu C, He T, Tan L, Zhu Y, Guo T, Wu H, Zhang H and Sun Y. An individualized protein-based prognostic model to stratify pediatric patients with papillary thyroid carcinoma. Nat Commun 2024; 15: 3560.","journal-title":"Nat Commun"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"447","DOI":"10.3892\/ol.2018.8691","article-title":"Carbon nanoparticles guide contralateral central neck dissection in patients with papillary thyroid cancer","volume":"16","author":"Yu","year":"2018","unstructured":"Yu W, Xu G, Sun J and Zhong N. Carbon nanoparticles guide contralateral central neck dissection in patients with papillary thyroid cancer. Oncol Lett 2018; 16: 447-452.","journal-title":"Oncol Lett"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1186\/s12880-022-00920-4","article-title":"Histogram-based analysis of diffusion-weighted imaging for predicting aggressiveness in papillary thyroid carcinoma","volume":"22","author":"Wei","year":"2022","unstructured":"Wei R, Zhuang Y, Wang L, Sun X, Dai Z, Ge Y, Wang H and Song B. Histogram-based analysis of diffusion-weighted imaging for predicting aggressiveness in papillary thyroid carcinoma. BMC Med Imaging 2022; 22: 188.","journal-title":"BMC Med Imaging"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1186\/s12957-020-01965-x","article-title":"PTC located in the upper pole is more prone to lateral lymph node metastasis and skip metastasis","volume":"18","author":"Dou","year":"2020","unstructured":"Dou Y, Hu D, Chen Y, Xiong W, Xiao Q and Su X. PTC located in the upper pole is more prone to lateral lymph node metastasis and skip metastasis. World J Surg Oncol 2020; 18: 188.","journal-title":"World J Surg Oncol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1007\/s00405-020-05787-1","article-title":"Predicting the factors associated with central lymph node metastasis in clinical node-negative (cN0) papillary thyroid microcarcinoma","volume":"277","author":"Zhang","year":"2020","unstructured":"Zhang C, Li BJ, Liu Z, Wang LL and Cheng W. Predicting the factors associated with central lymph node metastasis in clinical node-negative (cN0) papillary thyroid microcarcinoma. Eur Arch Otorhinolaryngol 2020; 277: 1191-1198.","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"ref28","doi-asserted-by":"publisher","unstructured":"Seong CY, Chai YJ, Lee SM, Kim SJ, Choi JY, Lee KE, Hwang KT, Park SW and Yi KH. Significance of distance between tumor and thyroid capsule as an indicator for central lymph node metastasis in clinically node negative papillary thyroid carcinoma patients. PLoS One 2018; 13: e0200166.","DOI":"10.1371\/journal.pone.0200166"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1186\/s13244-023-01550-2","article-title":"Deep learning predicts cervical lymph node metastasis in clinically node-negative papillary thyroid carcinoma","volume":"14","author":"Zhou","year":"2023","unstructured":"Zhou LQ, Zeng SE, Xu JW, Lv WZ, Mei D, Tu JJ, Jiang F, Cui XW and Dietrich CF. Deep learning predicts cervical lymph node metastasis in clinically node-negative papillary thyroid carcinoma. Insights Imaging 2023; 14: 222.","journal-title":"Insights Imaging"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"511","DOI":"10.3389\/fendo.2020.00511","article-title":"Predictive factors of central-compartment lymph node metastasis for clinical N0 papillary thyroid carcinoma with strap muscle invasion","volume":"11","author":"Xue","year":"2020","unstructured":"Xue S, Zhang L, Pang R, Wang P, Jin M, Guo L, Zhou Y, Dong B and Chen G. Predictive factors of central-compartment lymph node metastasis for clinical N0 papillary thyroid carcinoma with strap muscle invasion. Front Endocrinol (Lausanne) 2020; 11: 511.","journal-title":"Front Endocrinol (Lausanne)"}],"container-title":["American Journal of Translational Research"],"original-title":[],"link":[{"URL":"https:\/\/e-century.us\/files\/ajtr\/17\/7\/ajtr0165730.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T01:56:36Z","timestamp":1766022996000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-century.us\/files\/ajtr\/17\/7\/ajtr0165730.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":31,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.62347\/jvgt3596","relation":{},"ISSN":["1943-8141"],"issn-type":[{"type":"electronic","value":"1943-8141"}],"subject":[],"published":{"date-parts":[[2025]]}}}