{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T22:33:44Z","timestamp":1781735624264,"version":"3.54.5"},"reference-count":29,"publisher":"e-Century Publishing Corporation","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Transl Res"],"DOI":"10.62347\/keno8599","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T04:12:41Z","timestamp":1745899961000},"page":"2947-2956","source":"Crossref","is-referenced-by-count":1,"title":["Predictive value of cardiopulmonary exercise test parameters for atrial fibrillation risk in hypertrophic cardiomyopathy patients"],"prefix":"10.62347","volume":"17","author":[{"given":"Ling","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"48694","published-online":{"date-parts":[[2025]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1016\/j.echo.2024.02.010","article-title":"Obstruction in hypertrophic cardiomyopathy: many faces","volume":"37","author":"Abbasi","year":"2024","unstructured":"Abbasi M, Ong KC, Newman DB, Dearani JA, Schaff HV and Geske JB. Obstruction in hypertrophic cardiomyopathy: many faces. J Am Soc Echocardiogr 2024; 37: 613-625.","journal-title":"J Am Soc Echocardiogr"},{"key":"ref1","doi-asserted-by":"publisher","first-page":"399","DOI":"10.2459\/JCM.0000000000001616","article-title":"Management of hypertrophic cardiomyopathy","volume":"25","author":"Zhang","year":"2024","unstructured":"Zhang Y, Adamo M, Zou C, Porcari A, Tomasoni D, Rossi M, Merlo M, Liu H, Wang J, Zhou P, Metra M, Sinagra G and Zhang J. Management of hypertrophic cardiomyopathy. J Cardiovasc Med (Hagerstown) 2024; 25: 399-419.","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1585","DOI":"10.1093\/cvr\/cvaa124","article-title":"Abnormalities in sodium current and calcium homoeostasis as drivers of arrhythmogenesis in hypertrophic cardiomyopathy","volume":"116","author":"Coppini","year":"2020","unstructured":"Coppini R, Santini L, Olivotto I, Ackerman MJ and Cerbai E. Abnormalities in sodium current and calcium homoeostasis as drivers of arrhythmogenesis in hypertrophic cardiomyopathy. Cardiovasc Res 2020; 116: 1585-1599.","journal-title":"Cardiovasc Res"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1161\/CIRCULATIONAHA.123.065037","article-title":"Evolving contemporary management of atrial fibrillation in hypertrophic cardiomyopathy","volume":"148","author":"Rowin","year":"2023","unstructured":"Rowin EJ, Link MS, Maron MS and Maron BJ. Evolving contemporary management of atrial fibrillation in hypertrophic cardiomyopathy. Circulation 2023; 148: 1797-1811.","journal-title":"Circulation"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1918","DOI":"10.1016\/j.athoracsur.2021.08.081","article-title":"Patient-reported atrial fibrillation after septal myectomy for hypertrophic cardiomyopathy","volume":"113","author":"Sun","year":"2022","unstructured":"Sun D, Schaff HV, Nishimura RA, Geske JB, Dearani JA, Newman DB and Ommen SR. Patient-reported atrial fibrillation after septal myectomy for hypertrophic cardiomyopathy. Ann Thorac Surg 2022; 113: 1918-1924.","journal-title":"Ann Thorac Surg"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"5022","DOI":"10.1002\/ehf2.13563","article-title":"Clinical significance of new-onset atrial fibrillation in patients with hypertrophic cardiomyopathy","volume":"8","author":"Kubo","year":"2021","unstructured":"Kubo T, Baba Y, Ochi Y, Hirota T, Yamasaki N, Kawai K, Yamamoto K, Kondo F, Bando K, Yamada E, Furuno T, Yabe T, Doi YL and Kitaoka H. Clinical significance of new-onset atrial fibrillation in patients with hypertrophic cardiomyopathy. ESC Heart Fail 2021; 8: 5022-5030.","journal-title":"ESC Heart Fail"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1177\/2047487319828474","article-title":"Risk factors for atrial fibrillation in hypertrophic cardiomyopathy","volume":"28","author":"DJ","year":"2021","unstructured":"Philipson DJ, Rader F and Siegel RJ. Risk factors for atrial fibrillation in hypertrophic cardiomyopathy. Eur J Prev Cardiol 2021; 28: 658-665.","journal-title":"Eur J Prev Cardiol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"96","DOI":"10.31083\/j.rcm2503096","article-title":"Association between the albumin-to-globulin ratio and atrial fibrillation in patients with hypertrophic cardiomyopathy","volume":"25","author":"Yuan","year":"2024","unstructured":"Yuan Z, Zhang K, Li H, Wang S, Li X, Sun W, Hang F, Mei Y, Han R, Wang C, Lai Y, Wu Y and Zhang X. Association between the albumin-to-globulin ratio and atrial fibrillation in patients with hypertrophic cardiomyopathy. Rev Cardiovasc Med 2024; 25: 96.","journal-title":"Rev Cardiovasc Med"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1111\/jce.16210","article-title":"Aggressive treatment of atrial fibrillation in hypertrophic cardiomyopathy patients improve quality of life","volume":"35","author":"Naccarelli","year":"2024","unstructured":"Naccarelli GV and Popjes ED. Aggressive treatment of atrial fibrillation in hypertrophic cardiomyopathy patients improve quality of life. J Cardiovasc Electrophysiol 2024; 35: 664-666.","journal-title":"J Cardiovasc Electrophysiol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"727","DOI":"10.7150\/ijms.50167","article-title":"Thromboembolism in patients with hypertrophic cardiomyopathy","volume":"18","author":"Liu","year":"2021","unstructured":"Liu L, Liu Z, Chen X and He S. Thromboembolism in patients with hypertrophic cardiomyopathy. Int J Med Sci 2021; 18: 727-735.","journal-title":"Int J Med Sci"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1080\/14779072.2021.1985466","article-title":"Cardiopulmonary exercise testing as a vital sign in patients recovering from COVID-19","volume":"19","author":"Arena","year":"2021","unstructured":"Arena R and Faghy MA. Cardiopulmonary exercise testing as a vital sign in patients recovering from COVID-19. Expert Rev Cardiovasc Ther 2021; 19: 877-880.","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"Letnes JM, Nes BM and Wisløff U. Age-related decline in peak oxygen uptake: cross-sectional vs. longitudinal findings. A review. Int J Cardiol Cardiovasc Risk Prev 2023; 16: 200171.","DOI":"10.1016\/j.ijcrp.2023.200171"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1080\/13696998.2024.2367920","article-title":"The prognostic value of peak oxygen uptake in obstructive hypertrophic cardiomyopathy: a literature review to inform economic model development","volume":"27","author":"Butzner","year":"2024","unstructured":"Butzner M, Kinyik-Merena C, Aguiar M, Davison N, Shreay S and Masri A. The prognostic value of peak oxygen uptake in obstructive hypertrophic cardiomyopathy: a literature review to inform economic model development. J Med Econ 2024; 27: 817-825.","journal-title":"J Med Econ"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1186\/s12872-022-02935-9","article-title":"Coronary stenosis is a risk marker for impaired cardiac function on cardiopulmonary exercise test","volume":"22","author":"Li","year":"2022","unstructured":"Li S, Yuan Y, Zhao L, Lv T, She F, Liu F, Xue Y, Zhou B, Xie Y, Geng Y and Zhang P. Coronary stenosis is a risk marker for impaired cardiac function on cardiopulmonary exercise test. BMC Cardiovasc Disord 2022; 22: 486.","journal-title":"BMC Cardiovasc Disord"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.jad.2022.02.037","article-title":"Nomogram predicting bullying victimization in adolescents","volume":"303","author":"Lv","year":"2022","unstructured":"Lv J, Ren H, Guo X, Meng C, Fei J, Mei H and Mei S. Nomogram predicting bullying victimization in adolescents. J Affect Disord 2022; 303: 264-272.","journal-title":"J Affect Disord"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"Ommen SR, Mital S, Burke MA, Day SM, Deswal A, Elliott P, Evanovich LL, Hung J, Joglar JA, Kantor P, Kimmelstiel C, Kittleson M, Link MS, Maron MS, Martinez MW, Miyake CY, Schaff HV, Semsarian C and Sorajja P. 2020 AHA\/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: executive summary: a report of the american college of cardiology\/american heart association joint committee on clinical practice guidelines. Circulation 2020; 142: e533-e557.","DOI":"10.1161\/CIR.0000000000000938"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"501","DOI":"10.3390\/jcm13020501","article-title":"Atrial fibrillation in patients with hypertrophic cardiomyopathy and cardiac amyloidosis: from clinical management to catheter ablation indication","volume":"13","author":"Mistrulli","year":"2024","unstructured":"Mistrulli R, Ferrera A, Muthukkattil ML, Battistoni A, Gallo G, Barbato E, Spera FR and Magrì D. Atrial fibrillation in patients with hypertrophic cardiomyopathy and cardiac amyloidosis: from clinical management to catheter ablation indication. J Clin Med 2024; 13: 501.","journal-title":"J Clin Med"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"Palyam V, Azam AT, Odeyinka O, Alhashimi R, Thoota S, Ashok T and Sange I. Hypertrophic cardiomyopathy and atrial fibrillation: a review. Cureus 2022; 14: e21101.","DOI":"10.7759\/cureus.21101"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1161\/STROKEAHA.121.034213","article-title":"Ischemic stroke in patients with hypertrophic cardiomyopathy according to presence or absence of atrial fibrillation","volume":"53","author":"Fauchier","year":"2022","unstructured":"Fauchier L, Bisson A, Bodin A, Herbert J, Spiesser P, Pierre B, Clementy N, Bernard A, Babuty D and Lip GYH. Ischemic stroke in patients with hypertrophic cardiomyopathy according to presence or absence of atrial fibrillation. Stroke 2022; 53: 497-504.","journal-title":"Stroke"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"131575","DOI":"10.1016\/j.ijcard.2023.131575","article-title":"Prediction of incident atrial fibrillation in hypertrophic cardiomyopathy","volume":"395","author":"Losi","year":"2024","unstructured":"Losi MA, Monda E, Lombardi R, Lioncino M, Canciello G, Rubino M, Todde G, Caiazza M, Borrelli F, Fusco A, Cirillo A, Perillo EF, Sepe J, Pacella D, de Simone G, Calabro P, Esposito G and Limongelli G. Prediction of incident atrial fibrillation in hypertrophic cardiomyopathy. Int J Cardiol 2024; 395: 131575.","journal-title":"Int J Cardiol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.jchf.2024.09.008","article-title":"The clinical trajectory of nyha functional class I patients with obstructive hypertrophic cardiomyopathy","volume":"13","author":"Ahluwalia","year":"2025","unstructured":"Ahluwalia M, Liu J, Olivotto I, Parikh V, Ashley EA, Michels M, Ingles J, Lampert R, Stendahl JC, Colan SD, Abrams D, Pereira AC, Rossano JW, Ryan TD, Owens AT, Ware JS, Saberi S, Helms AS, Day S, Claggett B, Ho CY and Lakdawala NK. The clinical trajectory of nyha functional class I patients with obstructive hypertrophic cardiomyopathy. JACC Heart Fail 2025; 13: 332-343.","journal-title":"JACC Heart Fail"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"101414","DOI":"10.1016\/j.cpcardiol.2022.101414","article-title":"Mechanism and prevention of atrial remodeling and their related genes in cardiovascular disorders","volume":"48","author":"Sandeep","year":"2023","unstructured":"Sandeep B, Ding W, Huang X, Liu C, Wu Q, Su X, Gao K and Xiao Z. Mechanism and prevention of atrial remodeling and their related genes in cardiovascular disorders. Curr Probl Cardiol 2023; 48: 101414.","journal-title":"Curr Probl Cardiol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1111\/jce.15759","article-title":"Atrial fibrillation: epidemiology, pathophysiology, and clinical complications (literature review)","volume":"34","author":"KA","year":"2023","unstructured":"Bizhanov KA, Аbzaliyev KB, Baimbetov AK, Sarsenbayeva AB and Lyan E. Atrial fibrillation: epidemiology, pathophysiology, and clinical complications (literature review). J Cardiovasc Electrophysiol 2023; 34: 153-165.","journal-title":"J Cardiovasc Electrophysiol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1186\/s12931-024-02746-w","article-title":"Cardiopulmonary exercise test to detect cardiac dysfunction from pulmonary vascular disease","volume":"25","author":"Alotaibi","year":"2024","unstructured":"Alotaibi M, Yang JZ, Papamatheakis DG, McGuire WC, Fernandes TM and Morris TA. Cardiopulmonary exercise test to detect cardiac dysfunction from pulmonary vascular disease. Respir Res 2024; 25: 121.","journal-title":"Respir Res"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.36660\/abc.20220196","article-title":"NYHA classification and cardiopulmonary exercise test variables in patients with heart failure","volume":"118","author":"Costa","year":"2022","unstructured":"Costa RVC. NYHA classification and cardiopulmonary exercise test variables in patients with heart failure. Arq Bras Cardiol 2022; 118: 1124-1125.","journal-title":"Arq Bras Cardiol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.hlc.2018.12.007","article-title":"Cardiopulmonary exercise test parameters at three months after alcohol septal ablation in hypertrophic obstructive cardiomyopathy are associated with late clinical outcome","volume":"29","author":"Rigopoulos","year":"2020","unstructured":"Rigopoulos AG, Panou F, Sakadakis E, Frogoudaki A, Papadopoulou K, Triantafyllidi H, Ali M, Iliodromitis E, Rizos I and Noutsias M. Cardiopulmonary exercise test parameters at three months after alcohol septal ablation in hypertrophic obstructive cardiomyopathy are associated with late clinical outcome. Heart Lung Circ 2020; 29: 202-210.","journal-title":"Heart Lung Circ"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"15977","DOI":"10.1038\/s41598-020-71394-z","article-title":"Examining the impact of inducible ischemia on myocardial fibrosis and exercise capacity in hypertrophic cardiomyopathy","volume":"10","author":"Malahfji","year":"2020","unstructured":"Malahfji M, Senapati A, Debs D, Angulo C, Zhan Y, Nagueh SF and Shah DJ. Examining the impact of inducible ischemia on myocardial fibrosis and exercise capacity in hypertrophic cardiomyopathy. Sci Rep 2020; 10: 15977.","journal-title":"Sci Rep"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.ijcard.2018.10.055","article-title":"Predictors of outcome in heart failure patients with severe functional mitral regurgitation undergoing MitraClip treatment","volume":"284","author":"Baldi","year":"2019","unstructured":"Baldi C, Citro R, Silverio A, Di Maio M, De Rosa R, Bonadies D, Verolino G, Esposito L, Mastrogiovanni G, Di Muro MR, Piscione F and Galasso G. Predictors of outcome in heart failure patients with severe functional mitral regurgitation undergoing MitraClip treatment. Int J Cardiol 2019; 284: 50-58.","journal-title":"Int J Cardiol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"607","DOI":"10.21037\/jtd-22-24","article-title":"Diagnostic value of the cardiopulmonary exercise test in coronary artery disease","volume":"14","author":"Li","year":"2022","unstructured":"Li N, Liu J, Ren Y and Cheng J. Diagnostic value of the cardiopulmonary exercise test in coronary artery disease. J Thorac Dis 2022; 14: 607-613.","journal-title":"J Thorac Dis"}],"container-title":["American Journal of Translational Research"],"original-title":[],"link":[{"URL":"https:\/\/e-century.us\/files\/ajtr\/17\/4\/ajtr0162887.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T01:56:32Z","timestamp":1766022992000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-century.us\/files\/ajtr\/17\/4\/ajtr0162887.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":29,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.62347\/keno8599","relation":{},"ISSN":["1943-8141"],"issn-type":[{"value":"1943-8141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}