{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T01:25:33Z","timestamp":1777339533447,"version":"3.51.4"},"reference-count":25,"publisher":"e-Century Publishing Corporation","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Transl Res"],"DOI":"10.62347\/knte8578","type":"journal-article","created":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T21:43:45Z","timestamp":1712267025000},"page":"1009-1017","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy of levetiracetam combined with oxcarbazepine in the treatment of adults with temporal lobe epilepsy and its impact on memory and cognitive function"],"prefix":"10.62347","volume":"16","author":[{"given":"Zhangxia","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"48694","published-online":{"date-parts":[[2024]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Henning O, Heuser K, Larsen VS, Kyte EB, Kostov H, Marthinsen PB, Egge A, Alfstad KA and Nakken KO. Temporal lobe epilepsy. Tidsskr Nor Laegeforen 2023; 143.","DOI":"10.4045\/tidsskr.22.0369"},{"key":"ref1","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1111\/epi.16423","article-title":"Impaired vigilance networks in temporal lobe epilepsy: mechanisms and clinical implications","volume":"61","author":"DJ","year":"2020","unstructured":"Englot DJ, Morgan VL and Chang C. Impaired vigilance networks in temporal lobe epilepsy: mechanisms and clinical implications. Epilepsia 2020; 61: 189-202.","journal-title":"Epilepsia"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Guo A, Zhang H, Li H, Chiu A, Garcia-Rodriguez C, Lagos CF, Saez JC and Lau CG. Inhibition of connexin hemichannels alleviates neuroinflammation and hyperexcitability in temporal lobe epilepsy. Proc Natl Acad Sci U S A 2022; 119: e2213162119.","DOI":"10.1073\/pnas.2213162119"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Samson S, Moncomble C, Mere M, Vasseur R and Dupont S. Getting older with chronic temporal lobe epilepsy: what memory profile? Rev Neurol (Paris) 2020; 176: 439-443.","DOI":"10.1016\/j.neurol.2020.04.011"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1007\/s10548-022-00911-2","article-title":"Levetiracetam modulates EEG microstates in temporal lobe epilepsy","volume":"35","author":"Ricci","year":"2022","unstructured":"Ricci L, Croce P, Pulitano P, Boscarino M, Zappasodi F, Narducci F, Lanzone J, Sancetta B, Mecarelli O, Di Lazzaro V, Tombini M and Assenza G. Levetiracetam modulates EEG microstates in temporal lobe epilepsy. Brain Topogr 2022; 35: 680-691.","journal-title":"Brain Topogr"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"3035","DOI":"10.1016\/j.clinph.2021.08.024","article-title":"Machine learning for predicting levetiracetam treatment response in temporal lobe epilepsy","volume":"132","author":"Croce","year":"2021","unstructured":"Croce P, Ricci L, Pulitano P, Boscarino M, Zappasodi F, Lanzone J, Narducci F, Mecarelli O, Di Lazzaro V, Tombini M and Assenza G. Machine learning for predicting levetiracetam treatment response in temporal lobe epilepsy. Clin Neurophysiol 2021; 132: 3035-3042.","journal-title":"Clin Neurophysiol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.seizure.2020.10.018","article-title":"Current role of carbamazepine and oxcarbazepine in the management of epilepsy","volume":"83","author":"Beydoun","year":"2020","unstructured":"Beydoun A, DuPont S, Zhou D, Matta M, Nagire V and Lagae L. Current role of carbamazepine and oxcarbazepine in the management of epilepsy. Seizure 2020; 83: 251-263.","journal-title":"Seizure"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"335","DOI":"10.2217\/pgs-2022-0177","article-title":"Pharmacogenomics of oxcarbazepine in the treatment of epilepsy","volume":"24","author":"Yuan","year":"2023","unstructured":"Yuan Y, Zhang S, Yuan Y, Yan X, Zhang L and Ran YW. Pharmacogenomics of oxcarbazepine in the treatment of epilepsy. Pharmacogenomics 2023; 24: 335-343.","journal-title":"Pharmacogenomics"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1508","DOI":"10.1212\/WNL.0000000000000910","article-title":"Levetiracetam reduces abnormal network activations in temporal lobe epilepsy","volume":"83","author":"Wandschneider","year":"2014","unstructured":"Wandschneider B, Stretton J, Sidhu M, Centeno M, Kozak LR, Symms M, Thompson PJ, Duncan JS and Koepp MJ. Levetiracetam reduces abnormal network activations in temporal lobe epilepsy. Neurology 2014; 83: 1508-1512.","journal-title":"Neurology"},{"key":"ref9","unstructured":"Wang XQ, Zhang XD, Han YM, Shi XF, Lan ZB, Men XX and Pan YW. Clinical efficacy of gamma knife and surgery treatment of mesial temporal lobe epilepsy and their effects on EF-Tumt and EF-Tsmt expression. Eur Rev Med Pharmacol Sci 2017; 21: 1774-1779."},{"key":"ref10","unstructured":"Wang L, Song YL, Sun P, Li ZC and Zhao N. Analysis of EEG abnormalities of cognitive impairment and epileptic seizures in patients with epilepsy. Eur Rev Med Pharmacol Sci 2019; 23: 10964-10969."},{"key":"ref11","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1159\/000341785","article-title":"Radiosurgical treatment for epilepsy associated with cavernomas","volume":"27","author":"Leveque","year":"2013","unstructured":"Leveque M, Carron R, Bartolomei F and Regis J. Radiosurgical treatment for epilepsy associated with cavernomas. Prog Neurol Surg 2013; 27: 157-165.","journal-title":"Prog Neurol Surg"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"9709536","DOI":"10.1155\/2022\/9709536","article-title":"Correlation between sleep time, sleep quality, and emotional and cognitive function in the elderly","volume":"2022","author":"Liao","year":"2022","unstructured":"Liao H, Liao S, Gao YJ, Mu JP, Wang X and Chen DS. Correlation between sleep time, sleep quality, and emotional and cognitive function in the elderly. Biomed Res Int 2022; 2022: 9709536.","journal-title":"Biomed Res Int"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/j.neurol.2017.06.011","article-title":"Long-term memory deficits in temporal lobe epilepsy","volume":"173","author":"Tramoni-Negre","year":"2017","unstructured":"Tramoni-Negre E, Lambert I, Bartolomei F and Felician O. Long-term memory deficits in temporal lobe epilepsy. Rev Neurol (Paris) 2017; 173: 490-497.","journal-title":"Rev Neurol (Paris)"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.eplepsyres.2017.07.007","article-title":"Epileptologist&#x2019;s view: laser interstitial thermal ablation for treatment of temporal lobe epilepsy","volume":"142","author":"Kang","year":"2018","unstructured":"Kang JY and Sperling MR. Epileptologist&#x2019;s view: laser interstitial thermal ablation for treatment of temporal lobe epilepsy. Epilepsy Res 2018; 142: 149-152.","journal-title":"Epilepsy Res"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"2165","DOI":"10.1007\/s10072-020-04322-8","article-title":"Alterations in intra- and internetwork functional connectivity associated with levetiracetam treatment in temporal lobe epilepsy","volume":"41","author":"Pang","year":"2020","unstructured":"Pang XM, Liang XL, Zhou X, Liu JP, Zhang Z and Zheng JO. Alterations in intra- and internetwork functional connectivity associated with levetiracetam treatment in temporal lobe epilepsy. Neurol Sci 2020; 41: 2165-2174.","journal-title":"Neurol Sci"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"Nolan SJ, Muller M, Tudur Smith C and Marson AG. Oxcarbazepine versus phenytoin monotherapy for epilepsy. Cochrane Database Syst Rev 2013; CD003615.","DOI":"10.1002\/14651858.CD003615.pub3"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"Toyota T, Akamatsu N, Tanaka A, Shouzaki T, Tsuji S, Saito K and Tanaka Y. Mesial temporal lobe epilepsy as a neuropsychiatric syndrome of systemic lupus erythematosus. Epilepsia 2013; 54: e33-36.","DOI":"10.1111\/epi.12012"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"813140","DOI":"10.3389\/fneur.2022.813140","article-title":"craniotomy only for traumatic brain injury: a propensity-matched study of long-term outcomes in neuropsychology","volume":"13","author":"Guo","year":"2022","unstructured":"Guo Z, Ding W, Cao D, Chen Y and Chen J. Decompressive craniectomy vs. craniotomy only for traumatic brain injury: a propensity-matched study of long-term outcomes in neuropsychology. Front Neurol 2022; 13: 813140.","journal-title":"Front Neurol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"45","DOI":"10.17116\/neiro201882445","article-title":"Surgical treatment of epilepsy in patients with mediobasal temporal cavernous malformations","volume":"82","author":"Grigoryan","year":"2018","unstructured":"Grigoryan YA, Sitnikov AR, Grigoryan GY, Timoshenkov AV and Mishnyakova LP. Surgical treatment of epilepsy in patients with mediobasal temporal cavernous malformations. Zh Vopr Neirokhir Im N N Burdenko 2018; 82: 45-56.","journal-title":"Zh Vopr Neirokhir Im N N Burdenko"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/j.yebeh.2013.10.014","article-title":"Lesion side matters - an fMRI study on the association between neural correlates of watching dynamic fearful faces and their evaluation in patients with temporal lobe epilepsy","volume":"31","author":"Labudda","year":"2014","unstructured":"Labudda K, Mertens M, Steinkroeger C, Bien CG and Woermann FG. Lesion side matters - an fMRI study on the association between neural correlates of watching dynamic fearful faces and their evaluation in patients with temporal lobe epilepsy. Epilepsy Behav 2014; 31: 321-328.","journal-title":"Epilepsy Behav"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1592\/phco.21.11.904.34513","article-title":"Oxcarbazepine in the treatment of epilepsy","volume":"21","author":"Glauser","year":"2001","unstructured":"Glauser TA. Oxcarbazepine in the treatment of epilepsy. Pharmacotherapy 2001; 21: 904-919.","journal-title":"Pharmacotherapy"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"Weston J, Bromley R, Jackson CF, Adab N, Clayton-Smith J, Greenhalgh J, Hounsome J, McKay AJ, Tudur Smith C and Marson AG. Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child. Cochrane Database Syst Rev 2016; 11: CD010224.","DOI":"10.1002\/14651858.CD010224.pub2"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"Kharel S, Ojha R and Khanal S. Levetiracetam versus Oxcarbazepine as monotherapy in newly diagnosed focal epilepsy: a systematic review and meta-analysis. Brain Behav 2022; 12: e2779.","DOI":"10.1002\/brb3.2779"},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"Bresnahan R, Atim-Oluk M and Marson AG. Oxcarbazepine add-on for drug-resistant focal epilepsy. Cochrane Database Syst Rev 2020; 3: CD012433.","DOI":"10.1002\/14651858.CD012433.pub2"}],"container-title":["American Journal of Translational Research"],"original-title":[],"link":[{"URL":"https:\/\/e-century.us\/files\/ajtr\/16\/3\/ajtr0155151.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T01:52:20Z","timestamp":1766022740000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-century.us\/files\/ajtr\/16\/3\/ajtr0155151.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":25,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.62347\/knte8578","relation":{},"ISSN":["1943-8141"],"issn-type":[{"value":"1943-8141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}