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Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med 2009; 361: 455-467.","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1038\/nature00813","article-title":"Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum","volume":"418","author":"Wootton","year":"2002","unstructured":"Wootton JC, Feng X, Ferdig MT, Cooper RA, Mu J, Baruch DI, Magill AJ and Su XZ. Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum. 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