{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T19:19:56Z","timestamp":1792264796601,"version":"4.4.0"},"reference-count":28,"publisher":"e-Century Publishing Corporation","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Transl Res"],"DOI":"10.62347\/xvvc1010","type":"journal-article","created":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T23:49:50Z","timestamp":1713743390000},"page":"285-294","source":"Crossref","is-referenced-by-count":2,"title":["Application of mineral trioxide aggregate pulpotomy in the treatment of early pulpitis of primary molars"],"prefix":"10.62347","volume":"16","author":[{"given":"Wen","family":"Tao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"48694","published-online":{"date-parts":[[2024]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"75","DOI":"10.3892\/etm.2022.11774","article-title":"Wnt4 prevents apoptosis and inflammation of dental pulp cells induced by LPS by inhibiting the IKK\/NF-κB pathway","volume":"25","author":"Ni","year":"2022","unstructured":"Ni C, Wu G, Miao T and Xu J. Wnt4 prevents apoptosis and inflammation of dental pulp cells induced by LPS by inhibiting the IKK\/NF-κB pathway. Exp Ther Med 2022; 25: 75.","journal-title":"Exp Ther Med"},{"key":"ref1","doi-asserted-by":"publisher","first-page":"1198053","DOI":"10.3389\/fimmu.2023.1198053","article-title":"Identification and characterization of the ferroptosis-related ceRNA network in irreversible pulpitis","volume":"14","author":"Xie","year":"2023","unstructured":"Xie Q, Yu H, Liu Z, Zhou B, Fang F, Qiu W and Wu H. Identification and characterization of the ferroptosis-related ceRNA network in irreversible pulpitis. Front Immunol 2023; 14: 1198053.","journal-title":"Front Immunol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1111\/ipd.12495","article-title":"Success rates of preformed metal crowns placed with the modified and standard hall technique in a paediatric dentistry setting","volume":"29","author":"Midani","year":"2019","unstructured":"Midani R, Splieth CH, Mustafa Ali M, Schmoeckel J, Mourad SM and Santamaria RM. Success rates of preformed metal crowns placed with the modified and standard hall technique in a paediatric dentistry setting. Int J Paediatr Dent 2019; 29: 550-556.","journal-title":"Int J Paediatr Dent"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Agnihotry A, Thompson W, Fedorowicz Z, van Zuuren EJ and Sprakel J. Antibiotic use for irreversible pulpitis. Cochrane Database Syst Rev 2019; 5: CD004969.","DOI":"10.1002\/14651858.CD004969.pub5"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1111\/ipd.12568","article-title":"A retrospective study","volume":"30","author":"van der Weijden","year":"2020","unstructured":"van der Weijden FN, Hesse D, Americano GCA, Soviero VM and Bonifacio CC. The effect of pulp inflammation and premature extraction of primary molars on the successor permanent teeth. A retrospective study. Int J Paediatr Dent 2020; 30: 18-26.","journal-title":"Int J Paediatr Dent"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.joen.2021.10.005","article-title":"Response to pulp sensibility tests after full pulpotomy in permanent mandibular teeth with symptomatic irreversible pulpitis: a retrospective data analysis","volume":"48","author":"Aravind","year":"2022","unstructured":"Aravind A, R R, Sharma R, Rana A, Sharma S, Kumar V, Chawla A and Logani A. Response to pulp sensibility tests after full pulpotomy in permanent mandibular teeth with symptomatic irreversible pulpitis: a retrospective data analysis. J Endod 2022; 48: 80-86.","journal-title":"J Endod"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Mergoni G, Ganim M, Lodi G, Figini L, Gagliani M and Manfredi M. Single versus multiple visits for endodontic treatment of permanent teeth. Cochrane Database Syst Rev 2022; 12: CD005296.","DOI":"10.1002\/14651858.CD005296.pub4"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1111\/jcpe.12265","article-title":"Treatment of periodontal-endodontic lesions--a systematic review","volume":"41","author":"Schmidt","year":"2014","unstructured":"Schmidt JC, Walter C, Amato M and Weiger R. Treatment of periodontal-endodontic lesions--a systematic review. J Clin Periodontol 2014; 41: 779-790.","journal-title":"J Clin Periodontol"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Tomson PL, Vilela Bastos J, Jacimovic J, Jakovljevic A, Pulikkotil SJ and Nagendrababu V. Effectiveness of pulpotomy compared with root canal treatment in managing non-traumatic pulpitis associated with spontaneous pain: a systematic review and meta-analysis. Int Endod J 2023; 56 Suppl 3: 355-369.","DOI":"10.1111\/iej.13844"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"6743","DOI":"10.1007\/s00784-021-03960-2","article-title":"Vital pulp therapy in carious pulp-exposed permanent teeth: an umbrella review","volume":"25","author":"Leong","year":"2021","unstructured":"Leong DJX and Yap AU. Vital pulp therapy in carious pulp-exposed permanent teeth: an umbrella review. Clin Oral Investig 2021; 25: 6743-6756.","journal-title":"Clin Oral Investig"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/S0099-2399(06)81282-3","article-title":"Sealing ability of a mineral trioxide aggregate for repair of lateral root perforations","volume":"19","author":"SJ","year":"1993","unstructured":"Lee SJ, Monsef M and Torabinejad M. Sealing ability of a mineral trioxide aggregate for repair of lateral root perforations. J Endod 1993; 19: 541-544.","journal-title":"J Endod"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"Pedrini D, Panzarini SR, Tiveron ARF, Abreu VM, Sonoda CK, Poi WR and Brandini DA. Evaluation of cases of concussion and subluxation in the permanent dentition: a retrospective study. J Appl Oral Sci 2018; 26: e20170287.","DOI":"10.1590\/1678-7757-2017-0287"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"941826","DOI":"10.3389\/fbioe.2022.941826","article-title":"Modified mineral trioxide aggregate-a versatile dental material: an insight on applications and newer advancements","volume":"10","author":"Pushpalatha","year":"2022","unstructured":"Pushpalatha C, Dhareshwar V, Sowmya SV, Augustine D, Vinothkumar TS, Renugalakshmi A, Shaiban A, Kakti A, Bhandi SH, Dubey A, Rai AV and Patil S. Modified mineral trioxide aggregate-a versatile dental material: an insight on applications and newer advancements. Front Bioeng Biotechnol 2022; 10: 941826.","journal-title":"Front Bioeng Biotechnol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1007\/s00784-016-1798-z","article-title":"Prognostic factors in direct pulp capping with mineral trioxide aggregate or calcium hydroxide: 2- to 6-year follow-up","volume":"21","author":"&#xC7","year":"2017","unstructured":"Çalışkan MK and Güneri P. Prognostic factors in direct pulp capping with mineral trioxide aggregate or calcium hydroxide: 2- to 6-year follow-up. Clin Oral Investig 2017; 21: 357-367.","journal-title":"Clin Oral Investig"},{"key":"ref14","unstructured":"Zhao F, Wang YW, Wang L, Liu CX and Zhang WR. MTA pulpotomy and root canal therapy comparative analysis of clinical results in early pulpitis of molars. J Hunan Normal Univ (Med Sci) 2018; 15: 60-63."},{"key":"ref15","unstructured":"Gherunpong S, Tsakos G and Sheiham A. Developing and evaluating an oral health-related quality of life index for children; the CHILD-OIDP. Community Dent Health 2004; 21: 161-169."},{"key":"ref16","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1038\/s41368-022-00186-0","article-title":"Expert consensus on early childhood caries management","volume":"14","author":"Zou","year":"2022","unstructured":"Zou J, Du Q, Ge L, Wang J, Wang X, Li Y, Song G, Zhao W, Chen X, Jiang B, Mei Y, Huang Y, Deng S, Zhang H, Li Y and Zhou X. Expert consensus on early childhood caries management. Int J Oral Sci 2022; 14: 35.","journal-title":"Int J Oral Sci"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/s13005-020-00237-z","article-title":"Dental caries in primary and permanent teeth in children’s worldwide, 1995 to 2019: a systematic review and meta-analysis","volume":"16","author":"Kazeminia","year":"2020","unstructured":"Kazeminia M, Abdi A, Shohaimi S, Jalali R, Vaisi-Raygani A, Salari N and Mohammadi M. Dental caries in primary and permanent teeth in children’s worldwide, 1995 to 2019: a systematic review and meta-analysis. Head Face Med 2020; 16: 22.","journal-title":"Head Face Med"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"Li L, Yang X, Ju W, Li J and Yang X. Impact of primary molars with periapical disease on permanent successors: a retrospective radiographic study. Heliyon 2023; 9: e15854.","DOI":"10.1016\/j.heliyon.2023.e15854"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1964277","DOI":"10.1080\/20002297.2021.1964277","article-title":"Profuse diversity and acidogenicity of the candida-biome of deep carious lesions of Severe Early Childhood Caries (S-ECC)","volume":"13","author":"Fakhruddin","year":"2021","unstructured":"Fakhruddin KS, Perera Samaranayake L, Egusa H, Ngo HC and Pesee S. Profuse diversity and acidogenicity of the candida-biome of deep carious lesions of Severe Early Childhood Caries (S-ECC). J Oral Microbiol 2021; 13: 1964277.","journal-title":"J Oral Microbiol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1186\/s12903-022-02644-x","article-title":"Effectiveness of an integrated model of oral health-promoting schools in improving children’s knowledge and the KAP of their parents, Iran","volume":"22","author":"Tahani","year":"2022","unstructured":"Tahani B, Asgari I, Golkar S, Ghorani A, Hasan Zadeh Tehrani N and Arezoo Moghadam F. Effectiveness of an integrated model of oral health-promoting schools in improving children’s knowledge and the KAP of their parents, Iran. BMC Oral Health 2022; 22: 599.","journal-title":"BMC Oral Health"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.21037\/tp-22-260","article-title":"Retraction: efficacy and safety of mineral trioxide aggregate (MTA) pulpotomy for caries-exposed permanent teeth in children: a systematic review and meta-analysis","volume":"11","author":"Wang","year":"2022","unstructured":"Wang Y, Luo S, Tang W, Yang L, Liao Y and Liu F. Retraction: efficacy and safety of mineral trioxide aggregate (MTA) pulpotomy for caries-exposed permanent teeth in children: a systematic review and meta-analysis. Transl Pediatr 2022; 11: 1281-1282.","journal-title":"Transl Pediatr"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"354","DOI":"10.3390\/bioengineering10030354","article-title":"Bioceramics in endodontics: updates and future perspectives","volume":"10","author":"Dong","year":"2023","unstructured":"Dong X and Xu X. Bioceramics in endodontics: updates and future perspectives. Bioengineering (Basel) 2023; 10: 354.","journal-title":"Bioengineering (Basel)"},{"key":"ref23","unstructured":"Sanusi SY and Al-Bataynehb OB. Pulp therapy of primary dentition; its relevance despite insufficient histological evidence: a review. Iran Endod J 2023; 18: 15-40."},{"key":"ref24","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1186\/s12903-023-03171-z","article-title":"Evaluation of the reasons for failure in teeth with vital amputation treatment","volume":"23","author":"Yildiz","year":"2023","unstructured":"Yildiz S, Dogan MS and Dogan ME. Evaluation of the reasons for failure in teeth with vital amputation treatment. BMC Oral Health 2023; 23: 455.","journal-title":"BMC Oral Health"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"250","DOI":"10.34172\/joddd.2020.043","article-title":"Primary tooth pulpectomy overfilling by different placement techniques: a systematic review and meta-analysis","volume":"14","author":"Aminabadi","year":"2020","unstructured":"Aminabadi NA, Asl Aminabadi N, Jamali Z and Shirazi S. Primary tooth pulpectomy overfilling by different placement techniques: a systematic review and meta-analysis. J Dent Res Dent Clin Dent Prospects 2020; 14: 250-261.","journal-title":"J Dent Res Dent Clin Dent Prospects"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.3390\/ijerph20021191","article-title":"Survival analysis and risk factors of pulpectomy among children with severe early childhood caries treated under general anesthesia: a retrospective study","volume":"20","author":"SY","year":"2023","unstructured":"He SY, Li JY, Dai SS, Yang YH, Wen YF, Guo QY and Liu F. Survival analysis and risk factors of pulpectomy among children with severe early childhood caries treated under general anesthesia: a retrospective study. Int J Environ Res Public Health 2023; 20: 1191.","journal-title":"Int J Environ Res Public Health"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1186\/s12903-022-02553-z","article-title":"Survival analysis of pulpectomy in primary molars performed under dental general anaesthesia: a two-year retrospective study","volume":"22","author":"Xie","year":"2022","unstructured":"Xie Y, Wang Y, Ma Q, Li J, Chen Y, Yang R, Huang R, Zhang Q and Zou J. Survival analysis of pulpectomy in primary molars performed under dental general anaesthesia: a two-year retrospective study. BMC Oral Health 2022; 22: 597.","journal-title":"BMC Oral Health"}],"container-title":["American Journal of Translational Research"],"original-title":[],"link":[{"URL":"https:\/\/e-century.us\/files\/ajtr\/16\/1\/ajtr0152496.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T01:52:29Z","timestamp":1766022749000},"score":1,"resource":{"primary":{"URL":"https:\/\/e-century.us\/files\/ajtr\/16\/1\/ajtr0152496.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.62347\/xvvc1010","relation":{},"ISSN":["1943-8141"],"issn-type":[{"value":"1943-8141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}