{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T01:26:01Z","timestamp":1794360361828,"version":"4.9.0"},"reference-count":0,"publisher":"Tunisian Society of Medical Sciences","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tunis Med"],"abstract":"<jats:p>Introduction\u00a0: Les tumeurs thyro\u00efdiennes folliculaires non invasives avec noyaux de type papillaire\u00a0\u00abNIFTP\u00bb suscitent encore beaucoup de controverses concernant les crit\u00e8res de diagnostic histologiques et la prise en charge th\u00e9rapeutique.\nObjectif\u00a0: Etayer les sp\u00e9cificit\u00e9s clinicopathologiques des tumeurs NIFTP et discuter leur prise en charge th\u00e9rapeutique.\nM\u00e9thodes\u00a0: Etude r\u00e9trospective incluant 23 patients (26 nodules) op\u00e9r\u00e9s et suivis pour une tumeur NIFTP selon la classification de l\u2019OMS 2017 sur une p\u00e9riode de 5 ans (janvier 2016-d\u00e9cembre 2020).\nLa classification EUTIRADS 2017 a \u00e9t\u00e9 utilis\u00e9e pour la caract\u00e9risation des nodules \u00e0 l\u2019\u00e9chographie. La cytoponction a \u00e9t\u00e9 rapport\u00e9e selon le syst\u00e8me BETHESDA 2017.\u00a0\nR\u00e9sultats\u00a0: Tous nos patients \u00e9taient de sexe f\u00e9minin. L\u2019\u00e2ge moyen \u00e9tait de 47 ans [19-71]. Le d\u00e9lai moyen de consultation \u00e9tait de 9 mois [2mois\u20137ans]. Le nodule thyro\u00efdien \u00e9tait de d\u00e9couverte fortuite dans 6cas (26%). L\u2019examen avait r\u00e9v\u00e9l\u00e9 la pr\u00e9sence d\u2019un nodule isol\u00e9 de la thyro\u00efde dans 20 cas. Les nodules \u00e9taient class\u00e9s EUITRADS III ou IV dans 82%. La cytoponction, pratiqu\u00e9e dans 61% des cas, \u00e9tait class\u00e9e en Bethesda III dans 64% et IV dans 14%. Une thyro\u00efdectomie totale a \u00e9t\u00e9 pratiqu\u00e9e dans 74%. On a recens\u00e9 3 cas de NIFTP bifocal. L\u2019association \u00e0 un carcinome de la thyro\u00efde \u00e9tait not\u00e9e dans 7 cas. Aucune r\u00e9cidive locor\u00e9gionale ou \u00e0 distance n\u2019a \u00e9t\u00e9 rapport\u00e9e durant un suivi moyen de 3 ans et demi.\nConclusion\u00a0: Les r\u00e9visions r\u00e9centes des crit\u00e8res morphologiques du NIFTP incitent \u00e0 une adh\u00e9sion stricte aux crit\u00e8res histo-morphologiques d\u2019inclusion et d\u2019exclusion<\/jats:p>","DOI":"10.62438\/tunismed.v103i2.4918","type":"journal-article","created":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T17:12:05Z","timestamp":1765905125000},"source":"Crossref","is-referenced-by-count":2,"title":["NIFTP approche diagnostique et th\u00e9rapeutique"],"prefix":"10.62438","volume":"103","author":[{"given":"Nadia","family":"Romdhane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorra","family":"Chiboub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amira","family":"Khaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihene","family":"Gharsalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imen","family":"Zoghlami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safa","family":"Nefzaoui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Hariga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiraz","family":"Mbarek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"31112","published-online":{"date-parts":[[2025,2,1]]},"container-title":["La Tunisie M\u00e9dicale"],"original-title":[],"deposited":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T17:12:05Z","timestamp":1765905125000},"score":1,"resource":{"primary":{"URL":"https:\/\/latunisiemedicale.com\/index.php\/tunismed\/article\/view\/4918"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,2,1]]}},"URL":"https:\/\/doi.org\/10.62438\/tunismed.v103i2.4918","relation":{},"ISSN":["2724-7031","0041-4131"],"issn-type":[{"value":"2724-7031","type":"electronic"},{"value":"0041-4131","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2,1]]}}}