{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T22:11:40Z","timestamp":1778105500042,"version":"3.51.4"},"reference-count":0,"publisher":"Tunisian Society of Medical Sciences","issue":"01","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tunis Med"],"abstract":"<jats:p>Introduction\u00a0: Les infections urinaires communautaires caus\u00e9es par des souches d\u2019ent\u00e9robact\u00e9riesproductrices de b\u00e9ta-lactamase \u00e0 spectre \u00e9tendu (BLSE)sont en perp\u00e9tuelle augmentation chez l\u2019enfant, et repr\u00e9sentent un probl\u00e8me de sant\u00e9 publique qui impose de nouvelles strat\u00e9gies th\u00e9rapeutiques.\nObjectifs\u00a0: D\u00e9terminer la fr\u00e9quence des infections urinaires communautaires \u00e0 bact\u00e9ries productrices de BLSE chez l\u2019enfant tunisien et identifier les facteurs de risque associ\u00e9s \u00e0 ces infections\nM\u00e9thods:Il s\u2019agit d\u2019une \u00e9tude r\u00e9trospective analytique men\u00e9e au service de p\u00e9diatrie du CHU Sahloul de Sousse, entre janvier 2019 et d\u00e9cembre 2024, incluant les enfants de moins de 15 ans hospitalis\u00e9s pour infection urinaire confirm\u00e9e d\u2019origine communautaire.\nR\u00e9sultats:L'\u00e9tude a inclus 383\u00e9pisodes d\u2019IU dont 20,4% \u00e9taient caus\u00e9es par des souches d\u2019ent\u00e9robact\u00e9ries productrices de BLSE. L\u2019\u00e2ge m\u00e9dian \u00e9tait de 11 mois [3-66].Escherichia coli \u00e9tait la bact\u00e9rie la plus fr\u00e9quemment isol\u00e9e (80,4% des cas), suivie de Klebsiella pneumoniae(12,27%). En analyse multivari\u00e9e, le seul facteur retenu \u00e9tait l\u2019hospitalisation dans l'ann\u00e9e pr\u00e9c\u00e9dente(p=0,005).\nConclusion\u00a0:L\u2019augmentation alarmante des infection urinaires \u00e0 bact\u00e9ries BLSE impose la mise en place d\u2019une strat\u00e9gie concernant l\u2019usage non raisonn\u00e9 des antibiotiques et d\u2019une surveillance renforc\u00e9e de la r\u00e9sistance bact\u00e9rienne.<\/jats:p>","DOI":"10.62438\/tunismed.v104i01.6232","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T15:50:45Z","timestamp":1773157845000},"source":"Crossref","is-referenced-by-count":0,"title":["Profil \u00e9pid\u00e9miologique et facteurs de risque des infections urinaires communautaires \u00e0 ent\u00e9robact\u00e9ries BLSE chez l\u2019enfant Tunisien"],"prefix":"10.62438","volume":"104","author":[{"given":"Selsabil","family":"Nouir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7052-8829","authenticated-orcid":false,"given":"Sameh","family":"Mabrouk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sirine","family":"Mansar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Safa","family":"Hannachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farah","family":"Azouzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raja","family":"Boukadida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azza","family":"Harbi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajer","family":"Mokni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Houda","family":"Ajmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"31112","published-online":{"date-parts":[[2026,3,10]]},"container-title":["La Tunisie M\u00e9dicale"],"original-title":[],"deposited":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T21:33:11Z","timestamp":1778103191000},"score":1,"resource":{"primary":{"URL":"https:\/\/latunisiemedicale.com\/index.php\/tunismed\/article\/view\/6232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,10]]},"references-count":0,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2026,3,10]]}},"URL":"https:\/\/doi.org\/10.62438\/tunismed.v104i01.6232","relation":{},"ISSN":["2724-7031","0041-4131"],"issn-type":[{"value":"2724-7031","type":"electronic"},{"value":"0041-4131","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,10]]}}}