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Karbing DS, Kjaergaard S, Smith BW, Espersen K, Aller\u00f8d C, Andreassen S, et al. Variation in the PaO2\/FiO2 ratio with FiO2: mathematical and experimental description, and clinical relevance. Crit Care. 2007;11(6):R118.","journal-title":"Crit Care"},{"key":"key20250930121019_B40","article-title":"The effect of oxygen on the PaO2\/FiO2-ratio and shunt fraction in patients on mechanical ventilation: a physiological study","volume":"56","author":"de Vries","year":"2020","unstructured":"40. de Vries H, Coenen S, Kingma F, Heunks L, De Man A. The effect of oxygen on the PaO2\/FiO2-ratio and shunt fraction in patients on mechanical ventilation: a physiological study. Eur Respir J. 2020;56(Suppl 64):351.","journal-title":"Eur Respir J"},{"issue":"23","key":"key20250930121019_B41","first-page":"2526","article-title":"Acute respiratory distress syndrome: the Berlin Definition","volume":"307","author":"Ranieri","year":"2012","unstructured":"41. 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Pisani L, Zimatore C, Vercesi V, Smit M, Lippolis V, Grasso S, et al. Agreement between lung ultrasound and chest X-ray scoring in invasively ventilated ICU patients. Eur Respir J. 2019;54 suppl 63:OA3300.","journal-title":"Eur Respir J"},{"issue":"1","key":"key20250930121019_B44","doi-asserted-by":"crossref","DOI":"10.1186\/s13613-019-0601-0","article-title":"Estimated dead space fraction and the ventilatory ratio are associated with mortality in early ARDS","volume":"9","author":"Morales-Quinteros","year":"2019","unstructured":"44. Morales-Quinteros L, Schultz MJ, Bringu\u00e9 J, Calfee CS, Camprub\u00ed M, Cremer OL, et al.; MARS Consortium. Estimated dead space fraction and the ventilatory ratio are associated with mortality in early ARDS. 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Br J Anaesth. 2023;130(3):360-7.","journal-title":"Br J Anaesth"},{"key":"key20250930121019_B47","unstructured":"47. 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