{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T03:44:52Z","timestamp":1791949492067,"version":"4.3.4"},"reference-count":0,"publisher":"Annali Italiani di Chirurgia","issue":"10","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann. Ital. Chir."],"abstract":"<jats:p>AIM: The Tubeless comprehensive management model minimizes iatrogenic trauma by avoiding endotracheal intubation, chest tube placement, and urinary catheterization, while the robot-assisted thoracoscopic surgery system offers precise surgical manipulation and high-definition visualization. However, clinical evidence supporting the combination of these two approaches in early-stage lung cancer surgery remains limited. This study aimed to evaluate the short-term safety and clinical benefits of robot-assisted lobectomy based on the Tubeless concept in patients with early-stage lung cancer.METHODS: A total of 120 patients with early-stage non-small cell lung cancer who underwent robot-assisted lobectomy in our department between January 2022 and May 2025 were retrospectively analyzed. According to the perioperative management approach, patients were divided into the Tubeless group (n = 50), which received spontaneous breathing anesthesia without indwelling chest tubes or urinary catheters, and the traditional group (n = 70), which received double-lumen endotracheal intubation with indwelling chest tubes and urinary catheters. Baseline characteristics, intraoperative parameters, postoperative pain scores, postoperative complications, length of hospital stay, patient satisfaction, and 30-day readmission rates were compared between the two groups.RESULTS: No significant differences in baseline characteristics were observed between the two groups (p &gt; 0.05). Similarly, no significant differences were observed in intraoperative blood loss, operative time, number of lymph node dissection stations, or total number of lymph nodes dissected (p &gt; 0.05). Visual analogue scale (VAS) scores on postoperative days 1, 2, and 3 were significantly lower in the Tubeless group than in the traditional group (p &lt; 0.05). The overall incidence of postoperative complications was significantly lower in the Tubeless group than in the traditional group (p = 0.04). Total hospital stay and postoperative hospital stay were significantly shorter in the Tubeless group than in the traditional group (p &lt; 0.001). No significant difference was observed in the 30-day readmission rate between the two groups.CONCLUSIONS: Robot-assisted lobectomy combined with the Tubeless comprehensive management approach is feasible and is associated with favorable short-term perioperative outcomes in patients with early-stage lung cancer. However, long-term oncologic outcomes, such as recurrence-free and overall survival, require further investigation.<\/jats:p>","DOI":"10.62713\/aic.4714","type":"journal-article","created":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:47:15Z","timestamp":1791946035000},"source":"Crossref","is-referenced-by-count":0,"title":["Safety and Short-Term Clinical Outcomes of Robot-Assisted Lobectomy Based on the Tubeless Concept for Early-Stage Lung Cancer: A Retrospective Cohort Study"],"prefix":"10.62713","volume":"97","author":[{"given":"Zhenlin","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Thoracic surgery, The First Affiliated Hospital of Hunan Normal University, Hunan Provincial People\u2019s Hospital, 410000 Changsha, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhua","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Thoracic surgery, The First Affiliated Hospital of Hunan Normal University, Hunan Provincial People\u2019s Hospital, 410000 Changsha, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuxin","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Thoracic surgery, The First Affiliated Hospital of Hunan Normal University, Hunan Provincial People\u2019s Hospital, 410000 Changsha, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junting","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, The Fourth Hospital of Changsha, 410006 Changsha, Hunan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"48935","published-online":{"date-parts":[[2026,10,14]]},"container-title":["Annali Italiani di Chirurgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.annaliitalianidichirurgia.it\/journal\/AIC\/97\/10\/10.62713\/aic.4714","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:47:16Z","timestamp":1791946036000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.annaliitalianidichirurgia.it\/journal\/AIC\/97\/10\/10.62713\/aic.4714"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,14]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026]]}},"alternative-id":["S2239-253X(26)00227-0"],"URL":"https:\/\/doi.org\/10.62713\/aic.4714","relation":{},"ISSN":["0003-469X","2239-253X"],"issn-type":[{"value":"0003-469X","type":"print"},{"value":"2239-253X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,14]]},"article-number":"1912"}}