{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T17:10:33Z","timestamp":1784826633426,"version":"3.55.0"},"reference-count":0,"publisher":"George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Crit Care Med (Targu Mures)"],"published-print":{"date-parts":[[2026,7,30]]},"abstract":"<jats:p>Introduction: Neonatal gastric perforation (NGP) is a rare, life-threatening surgical emergency that predominantly affects premature and extremely low birth weight (ELBW) infants and remains associated with high mortality. Case presentation: A 600 g female infant born at 25\/26 weeks of gestational age developed necrotizing enterocolitis (NEC) during the third postnatal week and deteriorated with abdominal distension and pneumoperitoneum. Emergency laparotomy on day 24 revealed a single posterior gastric wall perforation with circumferential necrotic margins; the nasogastric tube tip was located at the defect. After minimal debridement, and primary two-layer closure, the infant survived a prolonged intensive care course complicated by recurrent sepsis, cholestasis, bronchopulmonary dysplasia, and later adhesive obstruction requiring adhesiolysis. Conclusions: Gastric perforation may represent an uncommon manifestation of severe NEC in ELBW infants. Delayed onset, necrotic margins, and systemic inflammatory deterioration may favor ischemic NEC-related injury over iatrogenic trauma. Early radiographic evaluation and prompt surgical exploration are crucial for survival. ? ? ?<\/jats:p>","DOI":"10.62838\/jccm-2026-0023","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T16:36:59Z","timestamp":1784824619000},"page":"453-458","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Necrotizing Enterocolitis with Gastric Perforation in a 24-day old preterm neonate"],"prefix":"10.62838","volume":"12","author":[{"name":"Institution Organizing University Doctoral Studies (IOSUD) George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures; Pediatric Surgery and Orthopedics Department, Targu Mures Emergency Clinical County Hospital, Targu Mure","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamas","family":"Toth","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reka","family":"Borka-Balas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Pediatric Clinic I, Targu Mures Emergency Clinical County Hospital; George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, Targu Mures","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Cucerea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Neonatology Department, Targu Mures Emergency Clinical County Hospital; George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, Targu Mures","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radu-Alexandru","family":"Prisca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Pediatric Surgery and Orthopedics Department, Targu Mures Emergency Clinical County Hospital, Targu Mures","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"49540","published-online":{"date-parts":[[2026,7,30]]},"container-title":["Journal of Critical Care Medicine"],"original-title":[],"link":[{"URL":"https:\/\/ojs.jccm.ro\/index.php\/JCCM\/article\/view\/38\/8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T16:37:06Z","timestamp":1784824626000},"score":1,"resource":{"primary":{"URL":"https:\/\/ojs.jccm.ro\/index.php\/JCCM\/article\/view\/38"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,30]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,7,30]]},"published-print":{"date-parts":[[2026,7,30]]}},"URL":"https:\/\/doi.org\/10.62838\/jccm-2026-0023","relation":{},"ISSN":["2393-1809","2393-1817"],"issn-type":[{"value":"2393-1809","type":"print"},{"value":"2393-1817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,30]]}}}