{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:37:24Z","timestamp":1791380244287,"version":"4.3.3"},"reference-count":10,"publisher":"MedWorks Media","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychopharmacol Bull"],"abstract":"<jats:p>Avoidant\/Restrictive Food Intake Disorder and misophonia seem to be overrepresented in autism spectrum disorder. Literature is mute on psychopharmacotherapy in these complex presentations. Here, authors report on a challenging case of low-functioning ASD child with comorbid ARFID and misophonia that responded favorably to a low-dose risperidone. This is followed by a brief discussion of purported pharmacodynamic mechanisms and relevant literature.<\/jats:p>","DOI":"10.64719\/pb.4430","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T11:39:16Z","timestamp":1761046756000},"page":"91-94","source":"Crossref","is-referenced-by-count":6,"title":["Low-Dose Risperidone for an Autistic Child with Comorbid ARFID and Misophonia"],"prefix":"10.64719","volume":"52","author":[{"given":"Ahmed","family":"Naguy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul-Mohsen","family":"Al-Humoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saxby","family":"Pridmore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Y","family":"Abuzeid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anubhuti","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalal","family":"Elsori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"54175","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Naguy A. Successful Use of Sertindole for Severe Behavioral Dyscontrol in a Pediatric Case of Syndromic Autism Spectrum Disorder. J Child Adolesc Psychophramacol. 2017;27(5):471\u2013472.","DOI":"10.1089\/cap.2016.0182"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Naguy A, Pridmore S, Alamiri B. Adjuvant Pitolisant in a Case With Early-Onset Schizophrenia. Clin Neuropharmacol. 2021;44(6):229\u2013230.","DOI":"10.1097\/WNF.0000000000000472"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Nelson CLM, Amsbaugh HM, Reilly JL et al. Beneficial and adverse effects of antipsychotic medication on cognitive flexibility are related to COMT genotype in first episode psychosis. Schizophr Res. 2018;202:212\u2013216.","DOI":"10.1016\/j.schres.2018.06.029"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Ghanizadeh A. Does risperidone improve hyperacusia in children with autism. Psychopharmacol Bull. 2009;42(1):108\u2013110.","DOI":"10.64719\/pb.4098"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Adanir AS, Coban OG, Ozatalay E. Increased Hyperacusis with Risperidone in an Autistic Child. Noro Psikiyatr Ars. 2017;54(2):187\u2013188.","DOI":"10.5152\/npa.2017.18062"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Naguy A, Roshdy R, Al-Mutairi A et al. Mirtazapine Improved Eating Patterns in Avoidant\/Restrictive Food Intake Disorder. Am J Ther. 2021 doi: 10.1097\/MJT.0000000000001338. doi: Online ahead of print.","DOI":"10.1097\/MJT.0000000000001338"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Inoue T, Otani R, Iguchi T et al. Prevalence of autism spectrum disorder and autistic traits in children with anorexia nervosa and avoidant\/restrictive food intake disorder. BioPsychoSocial Med. 2021;15:9. doi: 10.1186\/s13030-021-00212-3.","DOI":"10.1186\/s13030-021-00212-3"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Tunc S, Basbug HS. An extreme physical reaction in misophonia: stop smaking your mouth. Psychiatry and Clinical Psychopharmacology. 2017;27(4):416\u2013418.","DOI":"10.1080\/24750573.2017.1354656"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Zuschlag ZD, Leventhal KC. Rapid and Sustained Resolution of Misophonia-Type Hyperacusis With the Selective Serotonin Reuptake Inhibitor Sertraline. Prim Care Companion CNS Disord. 2021;23(3):20I02731.","DOI":"10.4088\/PCC.20l02731"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Jager I, de Koning P, Bost T et al. Misophonia: Phenomenology, comorbidity and demographics in a large sample. PLoS One. 2020;15(4):e0231390.","DOI":"10.1371\/journal.pone.0231390"}],"container-title":["Psychopharmacology Bulletin"],"original-title":[],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:30:25Z","timestamp":1791315025000},"score":1,"resource":{"primary":{"URL":"https:\/\/medworksmedia.com\/pb-article\/low-dose-risperidone-for-an-autistic-child-with-comorbid-arfid-and-misophonia\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,12]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,8,12]]}},"URL":"https:\/\/doi.org\/10.64719\/pb.4430","relation":{},"ISSN":["2472-2448"],"issn-type":[{"value":"2472-2448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,12]]}}}