{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:22:09Z","timestamp":1791379329255,"version":"4.3.2"},"reference-count":70,"publisher":"MedWorks Media","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychopharmacol Bull"],"abstract":"<jats:p>Background\nHypoxia, acidosis, and inflammation cause impairment of neuronal development due to lack of sufficient oxygen and nutrition, and there may be an increased risk of ASD in neonates with Neonatal Encephalopathy (NE). To evaluate the frequency of Autism Spectrum Disorder (ASD) in moderate and severe NE requiring therapeutic hypothermia at 18\u201336 months.\nMethods\nIn this prospective study, infants with moderate and severe NE requiring hypothermia were included.\nResults\nThroughout the study period, 33 of 85 neonates with NE admitted to our unit were included in the study. M-CHAT results of six infants included in the study showed positive and results of twenty-seven patients were negative. Four of six infants with a positive screening test completed a psychiatric examination, and two infants did not complete the clinical examination. The results of the examination showed that one infant was diagnosed with ASD, one was diagnosed with attention deficit hyperactivity disorder (ADHD), and two infants were diagnosed with no psychiatric disorder.\nConclusion\nOur results showed that the risk of ASD increases in infants with moderate and severe NE, and this relationship should be considered in long-term clinical follow-ups.<\/jats:p>","DOI":"10.64719\/pb.4610","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T11:23:34Z","timestamp":1761045814000},"page":"8-22","source":"Crossref","is-referenced-by-count":2,"title":["Autism Spectrum Disorder Screening at 18\u201336 Months in Infants with Moderate and Severe Neonatal Encephalopathy: Is Routine Screening Required?"],"prefix":"10.64719","volume":"50","author":[{"given":"Birol","family":"Karabulut","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Begum","family":"Sahbudak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"54175","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Lee AC, Kozuki N, Blencowe H, Vos T, Bahalim A, Darmstadt GL, Niermeyer S, Ellis M, Robertson NJ, Cousens S, Lawn JE. Intrapartumrelated neonatal encephalopathy incidence and impairment at regional and global levels for 2010 with trends from 1990. Pediatr Res. 2013 Dec;74(Suppl 1):50\u201372.","DOI":"10.1038\/pr.2013.206"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Vannucci RC, Perlman JM. Interventions for perinatal hypoxia-ischemic encephalopathy. Pediatrics. 1997;100:1004\u20131014.","DOI":"10.1542\/peds.100.6.1004"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Finer NN, Robertson CM, Richards RT et al. Hypoxic-ischemic encephalopathy in term neonates: perinatal factors and outcome. J Pediatr. 1981;98:112\u2013117.","DOI":"10.1016\/S0022-3476(81)80555-0"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Armstrong K, Franklin O, Sweetman D, Molloy EJ. Cardiovascular dysfunction in infants with neonatal encephalopathy. Arch Dis Child. 2012;97:372\u2013375.","DOI":"10.1136\/adc.2011.214205"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Barberi I, Calabro MP, Cordaro S, Gitto E, Sottile A, Prudente D, Bertuccio G, Consolo S. Myocardial ischaemia in neonates with perinatal asphyxia. Electrocardiographic, echocardiographic and enzymatic correlations. Eur J Pediatr. 1999;158:742\u2013747.","DOI":"10.1007\/s004310051192"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Fatemi A, Wilson MA, Johnston MV. Hypoxic-ischemic encephalopathy in the term infant. Clin Perinatol. 2009;36:835\u2013858. vii.","DOI":"10.1016\/j.clp.2009.07.011"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Shah PS, Perlman M. Time courses of intrapartum asphyxia: neonatal characteristics and outcomes. Am J Perinatol. 2009;26:39\u201344.","DOI":"10.1055\/s-0028-1095185"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Volpe JJ. Neonatal encephalopathy: an inadequate term for hypoxicischemic encephalopathy. Ann Neurol. 2012;72:156\u2013166.","DOI":"10.1002\/ana.23647"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Mwaniki MK, Atieno M, Lawn JE, Newton CR. Long-term neurodevelopmental outcomes after intrauterine and neonatal insults: a systematic review. Lancet. 2012;379:445\u2013452.","DOI":"10.1016\/S0140-6736(11)61577-8"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Kharoshankaya L, Stevenson NJ, Livingstone V, Murray DM, Murphy BP, Ahearne CE, Boylan GB. Seizure burden and neurodevelopmental outcome in neonates with hypoxic-ischemic encephalopathy. Dev Med Child Neurol. 2016;58:1242\u20131248.","DOI":"10.1111\/dmcn.13215"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Lindstrom K, Hallberg B, Blennow M, Wolff K, Fernell E, Westgren M. Moderate neonatal encephalopathy: pre- and perinatal risk factors and longterm outcome. Acta Obstet Gynecol Scand. 2008;87:503\u2013509.","DOI":"10.1080\/00016340801996622"},{"key":"ref12","unstructured":"American College of Obstetrics and Gynecology: Task force on Neonatal Encephalopathy 2003 Neonatal encephalopathy and cerebral palsy: Defining the pathogenesis and pathophysiology. American College of Obstetrics and Gynecology, Washington DC."},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Robertson CM, Finer NN. Long-term follow-up of term neonates with perinatal asphyxia. Clin Perinatol. 1993;20:483\u2013500.","DOI":"10.1016\/S0095-5108(18)30405-6"},{"key":"ref14","unstructured":"Robertson CM. 2nd edn. Oxford University Press; Oxford: 1997. Long-term follow-up of term infants with perinatal asphyxia; pp. 615\u2013630. In: Stevenson DK, Sunshine P (eds) Fetal and neonatal brain injury: mechanisms, management and the risks of practice."},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Walsh MC et al. Neonatal outcomes of moderately preterm infants compared to extremely preterm infants. Pediatr Res. 2017;82:297\u2013304.","DOI":"10.1038\/pr.2017.46"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"DuPont TL et al. Short-term outcomes of newborns with perinatal acidemia who are not eligible for systemic hypothermia therapy. J Pediatr. 2013;162:35\u201341.","DOI":"10.1016\/j.jpeds.2012.06.042"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Massaro AN et al. Short-term outcomes after perinatal hypoxic ischemic encephalopathy: a report from the Children\u2019s Hospitals Neonatal Consortium HIE focus group. J Perinatol. 2015;35:290\u2013296.","DOI":"10.1038\/jp.2014.190"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Murray DM, O\u2019Connor CM, Ryan CA, Korotchikova I, Boylan GB. Early EEG grade and outcome at 5 years after mild neonatal hypoxic ischemic encephalopathy. Pediatrics. 2016;138(4):e20160659.","DOI":"10.1542\/peds.2016-0659"},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Gonzalez FF, Miller SP. Does perinatal asphyxia impair cognitive function without cerebral palsy? Arch Dis Child. 2006;91:F454\u2013F459.","DOI":"10.1136\/adc.2005.092445"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Marlow N, Rose AS, Rands CE, Draper ES. Neuropsychological and educational problems at school age associated with neonatal encephalopathy. Arch Dis Child Fetal Neonatal Ed. 2005;90:F380\u2013F387.","DOI":"10.1136\/adc.2004.067520"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Moster D, Lie RT, Markestad T. Joint association of Apgar scores and early neonatal symptoms with minor disabilities at school age. Arch Dis Child Fetal Neonatal Ed. 2002;86:F16\u2013F21.","DOI":"10.1136\/fn.86.1.F16"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Getahun D, Fassett M, Wing D, Jacobsen S. 704: Association between perinatal ischemic-hypoxic conditions and autism spectrum disorder. Am J Obstet Gynecol. 2013a;208:S296.","DOI":"10.1016\/j.ajog.2012.10.042"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Getahun D, Rhoads GG, Demissie K, Lu SE, Quinn VP, Fassett MJ, Wing DA, Jacobsen S.J. In utero exposure to ischemic-hypoxic conditions and attention-deficit\/hyperactivity disorder. Pediatrics. 2013b;131:e53\u2013e61.","DOI":"10.1542\/peds.2012-1298"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"van Handel M, Swaab H, de Vries LS, Jongmans MJ. Long-term cognitive and behavioral consequences of neonatal encephalopathy following perinatal asphyxia: a review. Eur J Pediatr. 2007;166:645\u2013654.","DOI":"10.1007\/s00431-007-0437-8"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Modabbernia A, Mollon J, Boffetta P, Reichenberg A. Impaired gas exchange at birth and risk of intellectual disability and autism: a meta-analysis. J Autism Dev Disord. 2016;46:1847\u20131859.","DOI":"10.1007\/s10803-016-2717-5"},{"key":"ref26","doi-asserted-by":"crossref","unstructured":"Dixon G, Badawi N, Kurinczuk JJ et al. Early developmental outcomes after newborn encephalopathy. Pediatrics. 2002;109(1):26e33.","DOI":"10.1542\/peds.109.1.26"},{"key":"ref27","doi-asserted-by":"crossref","unstructured":"Maenner MJ. Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years\u2014Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2016. 2020:69. MMWR. Surveillance Summaries.","DOI":"10.15585\/mmwr.ss6903a1"},{"key":"ref28","doi-asserted-by":"crossref","unstructured":"Gardener H, Spiegelman D, Buka SL. Perinatal and neonatal risk factors for autism: a comprehensive meta-analysis. Pediatrics. 2011;128(2):344\u2013355.","DOI":"10.1542\/peds.2010-1036"},{"key":"ref29","doi-asserted-by":"crossref","unstructured":"Cheng J et al. Improving autism perinatal risk factors: A systematic review. Medical Hypotheses. 2019;127:26\u201333.","DOI":"10.1016\/j.mehy.2019.03.012"},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"Ou J et al. Prenatal Environment and Perinatal Factors Associated with Autism Spectrum Disorder. Glob Clin Transl Res. 2019;1(3):100\u2013108.","DOI":"10.36316\/gcatr.01.0015"},{"key":"ref31","doi-asserted-by":"crossref","unstructured":"Cordero C et al. Neonatal jaundice in association with autism spectrum disorder and developmental disorder. Journal of Perinatology. 2020;40(2):219\u2013225.","DOI":"10.1038\/s41372-019-0452-4"},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"Perlman JM. Summary proceedings from the neurology group on hypoxic-ischemic encephalopathy. Pediatrics. 2006;117(3 Pt 2):S28\u2013S33.","DOI":"10.1542\/peds.2005-0620E"},{"key":"ref33","doi-asserted-by":"crossref","unstructured":"Ferriero DM. Neonatal brain injury. N Engl J Med. 2004;351(19):1985\u20131995.","DOI":"10.1056\/NEJMra041996"},{"key":"ref34","doi-asserted-by":"crossref","unstructured":"Nijboer CH, Heijnen CJ, Groenendaal F, May MJ, van Bel F, Kavelaars A. A dual role of the NF-kappaB pathway in neonatal hypoxicischemic brain damage. Stroke. 2008;39(9):2578\u20132586.","DOI":"10.1161\/STROKEAHA.108.516401"},{"key":"ref35","doi-asserted-by":"publisher","unstructured":"Akisu M, Kumral A, Canpolat FE. Turkish Neonatal Society Guideline on neonatal encephalopathy. Turk Pediatri Ars. 2018;53(Suppl 1):S32\u2013S44. doi: 10.5152\/TurkPediatriArs.2018.01805. Published 2018 Dec 25. doi.","DOI":"10.5152\/TurkPediatriArs.2018.01805"},{"key":"ref36","doi-asserted-by":"crossref","unstructured":"Robins DI, Fein D, Barton MI et al. The modified check-list for autism in toddlers: an initial study investigating the early detection of autism and pervasive developmental disorders. Journal of Autism and Developmental Disorders. 2001;31:131\u2013144.","DOI":"10.1023\/A:1010738829569"},{"key":"ref37","doi-asserted-by":"crossref","unstructured":"Kara B, Mukaddes NM, Alt\u0131nkaya I et al. Using the modified checklist for autism in toddlers in a well-child clinic in Turkey: Adapting the screening method based on culture and setting. Autism. 2014; 18:331\u2013338.","DOI":"10.1177\/1362361312467864"},{"key":"ref38","doi-asserted-by":"crossref","unstructured":"Ravi S, Chandrasekaran V, Kattimani S, Subramanian M. Maternal and birth risk factors for children screening positive for autism spectrum disorders on M-CHAT-R. Asian J Psychiatr. 2016 Aug;22:17\u201321.","DOI":"10.1016\/j.ajp.2016.04.001"},{"key":"ref39","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association. fifth edition (DSM-V) Arlington: American Psychiatric Publishing; 2013. Diagnostic and statistical manual of mental disorders.","DOI":"10.1176\/appi.books.9780890425596"},{"key":"ref40","doi-asserted-by":"publisher","unstructured":"Oner O, Munir KM. Modifed Checklist for Autism in Toddlers Revised (MCHAT-R\/F) in an Urban Metropolitan Sample of Young Children in Turkey. J Autism Dev Disord. 2019 Aug 14; doi: 10.1007\/s10803-019-04160-4. doi.","DOI":"10.1007\/s10803-019-04160-4"},{"key":"ref41","doi-asserted-by":"crossref","unstructured":"Badawi N et al. Autism following a history of newborn encephalopathy: more than a coincidence. Dev Med Child Neurol. 2006;48:85\u201389.","DOI":"10.1017\/S001216220600020X"},{"key":"ref42","doi-asserted-by":"crossref","unstructured":"Duan G et al. Perinatal and background risk factors for childhood autism in central China. Psychiatry Res. 2014;220(1\u20132):410\u2013417.","DOI":"10.1016\/j.psychres.2014.05.057"},{"key":"ref43","doi-asserted-by":"crossref","unstructured":"Mamidala MP et al. Prenatal, perinatal and neonatal risk factors of Autism Spectrum Disorder: a comprehensive epidemiological assessment from India. Res Dev Disabil. 2013;34(9):3004\u20133013.","DOI":"10.1016\/j.ridd.2013.06.019"},{"key":"ref44","doi-asserted-by":"crossref","unstructured":"Froehlich-Santino W et al. Prenatal and perinatal risk factors in a twin study of autism spectrm disorders. Journal fo Psychiatric Research. 2014;54:100\u2013108.","DOI":"10.1016\/j.jpsychires.2014.03.019"},{"key":"ref45","doi-asserted-by":"crossref","unstructured":"Sugie Y et al. Neonatal factors in infants with Autistic Disorder and typically developing infants. Autism. 2005;9(5):487\u2013494.","DOI":"10.1177\/1362361305057877"},{"key":"ref46","doi-asserted-by":"crossref","unstructured":"Atladottir HO et al. A Descriptive Study on the Neonatal Morbidity Profile of Autism Spectrum Disorders, Including a Comparison with Other Neurodevelopmental Disorders. J Autism Dev Disord. 2015;45(8):2429\u20132442.","DOI":"10.1007\/s10803-015-2408-7"},{"key":"ref47","doi-asserted-by":"crossref","unstructured":"Low JA, Galbraith RS, Muir DW, Killen HL, Pater EA, Karchmar EJ. Motor and cognitive deficits after intrapartum asphyxia in the mature fetus. Am J Obstet Gynecol. 1988;158(2):356\u2013361.","DOI":"10.1016\/0002-9378(88)90154-8"},{"key":"ref48","doi-asserted-by":"crossref","unstructured":"Schieve LA, Clayton HB, Durkin MS, Wingate MS, Drews-Botsch C. Comparison of perinatal risk factors associated with autism spectrum disorder (ASD), intellectual disability (ID), and co-occurring ASD and ID. Journal of Autism and Developmental Disorders. 2015;45(8):2361\u20132372.","DOI":"10.1007\/s10803-015-2402-0"},{"key":"ref49","doi-asserted-by":"crossref","unstructured":"Aibar L, Puertas A, Valverde M, Carrillo MP, Montoya F. Fetal sex and perinatal outcomes. J Perinat Med. 2012;40:271e6.","DOI":"10.1515\/jpm-2011-0137"},{"key":"ref50","doi-asserted-by":"crossref","unstructured":"Di Renzo GC, Rosati A, Sarti RD, Cruciani L, Cutuli AM. Does fetal sex affect pregnancy outcome. Gend Med. 2007;4:19e30.","DOI":"10.1016\/S1550-8579(07)80004-0"},{"key":"ref51","doi-asserted-by":"crossref","unstructured":"Vatten LJ, Skj\u00e6rven R. Offspring sex and pregnancy outcome by length of gestation. Early Hum Dev. 2004;76:47e54.","DOI":"10.1016\/j.earlhumdev.2003.10.006"},{"key":"ref52","doi-asserted-by":"crossref","unstructured":"Stevenson DK, Verter J, Fanaroff AA, Oh W, Ehrenkranz RA, Shankaran S et al. Sex differences in outcomes of very low birthweight infants: the newborn male disadvantage. Arch Dis Child Fetal Neonatal Ed. 2000;83:F182e5.","DOI":"10.1136\/fn.83.3.F182"},{"key":"ref53","unstructured":"Barkovich AJ. MR and CT evaluation of profound neonatal and infantile asphyxia. Am J Neuroradiol. 1992;13:959\u2013972."},{"key":"ref54","doi-asserted-by":"crossref","unstructured":"Gadian DG, Aicardi J, Watkins KE, Porter DA, Mishkin M, Vargha-Khadem F. Developmental amnesia associated with early hypoxic-ischaemic injury. Brain. 2000;123:499\u2013507.","DOI":"10.1093\/brain\/123.3.499"},{"key":"ref55","doi-asserted-by":"crossref","unstructured":"Maneru C, Serra-Grabulosa JM, Junque C, Salgado-Pineda P, Bargallo N, Olondo M, Botet-Mussons F, Tallada M, Mercader JM. Residual hippocampal atrophy in asphyxiated term neonates. J Neuroimaging. 2003;13(1):68\u201374.","DOI":"10.1177\/1051228402239720"},{"key":"ref56","doi-asserted-by":"crossref","unstructured":"Rademakers RP, van der Knaap MS, Verbeeten B Jr, Barth PG, Valk J. Central cortico-subcortical involvement: a distinct pattern of brain damage caused by perinatal and postnatal asphyxia in term infants. J Comput Assist Tomogr. 1995;19:256\u2013263.","DOI":"10.1097\/00004728-199503000-00017"},{"key":"ref57","doi-asserted-by":"crossref","unstructured":"Toft PB. Prenatal and perinatal striatal injury: a hypothetical cause of attention-deficit-hyperactivity disorder. Pediatr Neurol. 1999;21:602\u2013610.","DOI":"10.1016\/S0887-8994(99)00046-6"},{"key":"ref58","doi-asserted-by":"crossref","unstructured":"de Haan M, Wyatt JS, Roth S, Vargha-Khadem F, Gadian D, Mishkin M. Brain and cognitive-behavioural development after asphyxia at term birth. Dev Sci. 2006;9(4):350\u2013358.","DOI":"10.1111\/j.1467-7687.2006.00499.x"},{"key":"ref59","doi-asserted-by":"crossref","unstructured":"DeLong GR. Autism, amnesia, hippocampus, and learning. Neurosci Biobehav Rev. 1992;16:63\u201370.","DOI":"10.1016\/S0149-7634(05)80052-1"},{"key":"ref60","doi-asserted-by":"crossref","unstructured":"Dilenge ME, Majnemer A, Shevell MI. Long-term developmental outcome of asphyxiated term neonates. J Child Neurol. 2001;16:781\u2013792.","DOI":"10.1177\/08830738010160110201"},{"key":"ref61","doi-asserted-by":"crossref","unstructured":"Lou HC. Etiology and pathogenesis of attention-deficit hyperactivity disorder (ADHD): significance of prematurity and perinatal hypoxic-haemodynamic encephalopathy. Acta Paediatr. 1996;85:1266\u20131271.","DOI":"10.1111\/j.1651-2227.1996.tb13909.x"},{"key":"ref62","doi-asserted-by":"crossref","unstructured":"Van Petten C. Relationship between hippocampal volume and memory ability in healthy individuals across the lifespan: review and meta-analysis. Neuropsychologia. 2004;42(10):1394\u20131413.","DOI":"10.1016\/j.neuropsychologia.2004.04.006"},{"key":"ref63","doi-asserted-by":"crossref","unstructured":"Eaves LC, Ho HH. Brief report: Stability and change in cognitive and behavioral characteristics of autism through childhood. Journal of Autism and Developmental Disorders. 1996;26:557\u2013569.","DOI":"10.1007\/BF02172276"},{"key":"ref64","doi-asserted-by":"publisher","unstructured":"Dawson G et al. Randomized, controlled trial of an intervention for toddlers with autism: The Early Start Denver Model. Pediatrics. 2010;125:e17\u2013e23. doi: 10.1542\/peds.2009-0958.","DOI":"10.1542\/peds.2009-0958"},{"key":"ref65","doi-asserted-by":"publisher","unstructured":"Zwaigenbaum L et al. Early intervention for children with autism spectrum disorder under 3 years of age: Recommendations for practice and research. Pediatrics. 2015;136(Suppl 1):S60\u2013S81. doi: 10.1542\/peds.2014-3667E.","DOI":"10.1542\/peds.2014-3667E"},{"key":"ref66","doi-asserted-by":"crossref","unstructured":"Robins D. Screening for autism spectrum disorders in primary care settings. Autism. 2008;12:537\u2013556.","DOI":"10.1177\/1362361308094502"},{"key":"ref67","doi-asserted-by":"crossref","unstructured":"Miller JS, Gabrielson T, Villalobos M et al. The each child study: systematic screening for autism spectrum disorders in a pediatric setting. Pediatrics. 2011;127:866\u2013871.","DOI":"10.1542\/peds.2010-0136"},{"key":"ref68","doi-asserted-by":"publisher","unstructured":"Worley JA, Matson JL, Mahan S, Kozlowski AM, Neal D. 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