{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"medRxiv"}],"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T13:09:41Z","timestamp":1771679381834,"version":"3.50.1"},"posted":{"date-parts":[[2026,2,19]]},"group-title":"Epidemiology","reference-count":23,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2026,2,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                <jats:p>\n                  We evaluated the probability of need for public health action against trachoma in Esmeraldas province, Ecuador. Compared to global references, seroconversion rates to\n                  <jats:italic>Chlamydia trachomatis<\/jats:italic>\n                  Pgp3 in children suggest high probability of action needed in rural villages (91%) and lower in more urban areas (32%), motivating further trachoma assessment.\n                <\/jats:p>","DOI":"10.64898\/2026.02.18.26346552","type":"posted-content","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T03:30:11Z","timestamp":1771558211000},"source":"Crossref","is-referenced-by-count":0,"title":["Use of serology to assess the probability of public health action needed for trachoma in coastal Ecuador"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4285-2255","authenticated-orcid":false,"given":"Everlyn","family":"Kamau","sequence":"first","affiliation":[{"name":"Francis I. Proctor Foundation, University of California, San Francisco, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1811-7808","authenticated-orcid":false,"given":"Lesly","family":"Simba\u00f1a Vivanco","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Universidad de San Francisco de Quito, Quito, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2515-5227","authenticated-orcid":false,"given":"Stuart","family":"Torres Ayala","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Universidad de San Francisco de Quito, Quito, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6137-9275","authenticated-orcid":false,"given":"Nikolina","family":"Walas","sequence":"additional","affiliation":[{"name":"Francis I. 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Brook","family":"Goodhew","sequence":"additional","affiliation":[{"name":"Division of Parasitic Diseases and Malaria, United States Centers for Disease Control and Prevention, Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9417-5562","authenticated-orcid":false,"given":"Diana L.","family":"Martin","sequence":"additional","affiliation":[{"name":"Division of Parasitic Diseases and Malaria, United States Centers for Disease Control and Prevention, Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadley","family":"Burroughs","sequence":"additional","affiliation":[{"name":"Francis I. Proctor Foundation, University of California, San Francisco, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0286-0747","authenticated-orcid":false,"given":"Manuel","family":"Calvopi\u00f1a","sequence":"additional","affiliation":[{"name":"Universidad de las Americas, Facultad de Medicina, Carrera de Medicina, Quito, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1519-7275","authenticated-orcid":false,"given":"William","family":"Cevallos","sequence":"additional","affiliation":[{"name":"Universidad Central del Ecuador, Instituto de Biomedicina, Quito, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1250-2879","authenticated-orcid":false,"given":"Sandra","family":"Vivero","sequence":"additional","affiliation":[{"name":"Universidad Central del Ecuador, Instituto de Biomedicina, Quito, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6769-0403","authenticated-orcid":false,"given":"Victoria","family":"Nipaz","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Universidad de San Francisco de Quito, Quito, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0222-6487","authenticated-orcid":false,"given":"Josefina","family":"Coloma","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7889-3852","authenticated-orcid":false,"given":"Gwenyth O.","family":"Lee","sequence":"additional","affiliation":[{"name":"Rutgers Global Health Institute and Department of Biostatistics and Epidemiology, School of Public Health, Rutgers University, New Brunswick, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2617-9021","authenticated-orcid":false,"given":"Gabriel","family":"Trueba","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Universidad de San Francisco de Quito, Quito, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8019-296X","authenticated-orcid":false,"given":"Joseph N.S.","family":"Eisenberg","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0968-9401","authenticated-orcid":false,"given":"Karen","family":"Levy","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6105-7295","authenticated-orcid":false,"given":"Benjamin F.","family":"Arnold","sequence":"additional","affiliation":[{"name":"Francis I. 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