{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"medRxiv"}],"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T07:56:22Z","timestamp":1775634982077,"version":"3.50.1"},"posted":{"date-parts":[[2026,4,4]]},"group-title":"Endocrinology (including Diabetes Mellitus and Metabolic Disease)","reference-count":2,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T00:00:00Z","timestamp":1775260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2026,4,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                <jats:p>\n                  The ability to understand and affect the course of complex, multi-system diseases like diabetes has been limited by a lack of well-designed, high-quality and large multimodal datasets. The NIH Bridge2AI AI-READI project (\n                  <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/aireadi.org\">aireadi.org<\/jats:ext-link>\n                  ) aims to address this shortfall by generating an AI-ready dataset to support AI discoveries in type 2 diabetes mellitus (T2DM). This manual of procedures provides a detailed description of the AI-READI protocol.\n                <\/jats:p>","DOI":"10.64898\/2026.03.30.26349552","type":"posted-content","created":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T15:45:13Z","timestamp":1775317513000},"source":"Crossref","is-referenced-by-count":0,"title":["A Manual of Procedures for the Generation of the AI-Ready and Exploratory Atlas for Diabetes Insights (AI-READI) Database"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4008-7182","authenticated-orcid":false,"given":"Dawn S.","family":"Matthies","sequence":"first","affiliation":[{"name":"Department of Ophthalmology & Visual Sciences, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0248-7647","authenticated-orcid":false,"given":"Jeffrey C.","family":"Edberg","sequence":"additional","affiliation":[{"name":"Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5271-7690","authenticated-orcid":false,"given":"Sally L.","family":"Baxter","sequence":"additional","affiliation":[{"name":"Division of Ophthalmology Informatics and Data Science, Hamilton Glaucoma Center, Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California, San Diego, La Jolla, CA, USA"},{"name":"Division of Biomedical Informatics, Department of Medicine, University of California, San Diego, La Jolla, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7452-1648","authenticated-orcid":false,"given":"Aaron Y.","family":"Lee","sequence":"additional","affiliation":[{"name":"John F. Hardesty MD Department of Ophthalmology and Visual Sciences, Washington University, St. Louis, MO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1994-7213","authenticated-orcid":false,"given":"Cecilia S.","family":"Lee","sequence":"additional","affiliation":[{"name":"John F. Hardesty MD Department of Ophthalmology and Visual Sciences, Washington University, St. Louis, MO"},{"name":"University of Washington Department of Ophthalmology, Seattle, WA, The Roger and Angie Karalis Johnson Retina Center, Seattle, WA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9592-1133","authenticated-orcid":false,"suffix":"Jr.","given":"Gerald","family":"McGwin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology & Visual Sciences, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL"},{"name":"Department of Epidemiology, University of Alabama at Birmingham, Birmingham AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4137-3834","authenticated-orcid":false,"given":"Julia P.","family":"Owen","sequence":"additional","affiliation":[{"name":"John F. Hardesty MD Department of Ophthalmology and Visual Sciences, Washington University, St. Louis, MO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1143-5224","authenticated-orcid":false,"given":"Linda M.","family":"Zangwill","sequence":"additional","affiliation":[{"name":"Division of Ophthalmology Informatics and Data Science, Hamilton Glaucoma Center, Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California, San Diego, La Jolla, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3424-011X","authenticated-orcid":false,"given":"Cynthia","family":"Owsley","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology & Visual Sciences, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"54368","reference":[{"key":"2026040800251100000_2026.03.30.26349552v1.1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2024-097449"},{"key":"2026040800251100000_2026.03.30.26349552v1.2","first-page":"103729","article-title":"Navigating open data sharing and privacy in the age of clinical AI research: from reidentification to pseudo-reidentification","volume":"91","year":"2025","journal-title":"EClinicalMedicine"}],"container-title":[],"original-title":[],"link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.64898\/2026.03.30.26349552","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T07:25:16Z","timestamp":1775633116000},"score":1,"resource":{"primary":{"URL":"http:\/\/medrxiv.org\/lookup\/doi\/10.64898\/2026.03.30.26349552"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,4]]},"references-count":2,"URL":"https:\/\/doi.org\/10.64898\/2026.03.30.26349552","relation":{},"subject":[],"published":{"date-parts":[[2026,4,4]]},"subtype":"preprint"}}