{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"medRxiv"}],"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T21:50:03Z","timestamp":1776117003110,"version":"3.50.1"},"posted":{"date-parts":[[2026,4,10]]},"group-title":"Sports Medicine","reference-count":63,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2026,4,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Musculoskeletal conditions have high, and increasing, incidence and prevalence. Although there are many clinical guidelines available for common conditions, most are poor quality and sparsely adopted into practice. We aim to improve patient outcomes by developing robust Best Practice Guidelines (BPG) to get research findings into practice for a range of common musculoskeletal conditions.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Methods and analysis<\/jats:title>\n                  <jats:p>Mixed methods with systematic review of high-quality studies and qualitative elicitation of both patient\u2019s perspectives and expert clinical reasoning through in-depth interviews will form the basis for the BPGs. A segregated convergent synthesis, informed throughout by stakeholder engagement, will guide the format and structure of the BPGs.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Ethics, outputs and dissemination<\/jats:title>\n                  <jats:p>Ethical approval for the qualitative studies and implementation events will be obtained from university and health service research ethics committees. Educational packages for each BPG condition will be hosted online and be available for students, clinicians, and education providers. Dissemination will follow traditional routes including publications and presentations; alongside innovative approaches such as collaboration with higher education institutions, online hosting, adoption by professional bodies, and a social media campaign. Implementation will occur adaptively in multiple national contexts to reflect local requirements and resources, deploying participatory and implementation methods that are contextually and culturally appropriate.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>KEY MESSAGES<\/jats:title>\n                  <jats:list list-type=\"bullet\">\n                    <jats:list-item>\n                      <jats:p>\n                        <jats:bold>What is already known on this topic<\/jats:bold>\n                        \u2013 Clinical guidelines for the management of musculoskeletal conditions are common, but have limitations regarding quality, applicability, editorial independence, and patient perspective. They are rarely adopted into clinical practice.\n                      <\/jats:p>\n                    <\/jats:list-item>\n                    <jats:list-item>\n                      <jats:p>\n                        <jats:bold>What this study adds<\/jats:bold>\n                        \u2013 We have developed a robust (supported by Patient and Participant Involvement) mixed-methods approach that integrates the three components of evidence-based medicine: synthesis of high-quality evidence, patients\u2019 perspectives\/values, and expert clinical reasoning. We have also developed an education, dissemination, and implementation approach to facilitate international adoption of these guidelines.\n                      <\/jats:p>\n                    <\/jats:list-item>\n                    <jats:list-item>\n                      <jats:p>\n                        <jats:bold>How this study might affect research, practice or policy<\/jats:bold>\n                        \u2013 The guideline development methods will integrate the three pillars of evidence-based practice and ensure they are robust and clinically applicable. Creation of educational material combined with an implementation and dissemination plan will support adoption into clinical practice of different countries and cultures, designed to lead to improved patient outcomes.\n                      <\/jats:p>\n                    <\/jats:list-item>\n                  <\/jats:list>\n                <\/jats:sec>","DOI":"10.64898\/2026.04.09.26350486","type":"posted-content","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T20:30:17Z","timestamp":1775853017000},"source":"Crossref","is-referenced-by-count":0,"title":["Data to Practice (D2P). Protocol for the development, dissemination and initial implementation of best practice guides for common musculoskeletal conditions: a mixed-methods study"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7045-3644","authenticated-orcid":false,"given":"Dylan","family":"Morrissey","sequence":"first","affiliation":[{"name":"Sports and Exercise Medicine, Queen Mary University of London, London, UK"},{"name":"Physiotherapy Department, Barts Health NHS Trust, London, UK"},{"name":"Podium Analytics, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faiza","family":"Sharif","sequence":"additional","affiliation":[{"name":"Sports and Exercise Medicine, Queen Mary University of London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angie","family":"Fearon","sequence":"additional","affiliation":[{"name":"Sports and Exercise Medicine, Queen Mary University of London, London, UK"},{"name":"University of Canberra Research Institute for Sport and Exercise, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0651-3758","authenticated-orcid":false,"given":"Bradley Stephen","family":"Neal","sequence":"additional","affiliation":[{"name":"Sports and Exercise Medicine, Queen Mary University of London, London, UK"},{"name":"Physiotherapy Department, Barts Health NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1975-5871","authenticated-orcid":false,"given":"Tobias","family":"Bremer","sequence":"additional","affiliation":[{"name":"Sports and Exercise Medicine, Queen Mary University of London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9663-0696","authenticated-orcid":false,"given":"Paul","family":"Swinton","sequence":"additional","affiliation":[{"name":"School of Health, Robert Gordon University, Aberdeen, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5999-4001","authenticated-orcid":false,"given":"Phillip","family":"Newman","sequence":"additional","affiliation":[{"name":"University of Canberra Research Institute for Sport and Exercise, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1732-9606","authenticated-orcid":false,"given":"Simon","family":"Lack","sequence":"additional","affiliation":[{"name":"Sports and Exercise Medicine, Queen Mary University of London, London, UK"},{"name":"Physiotherapy Department, Barts Health NHS Trust, London, UK"},{"name":"Pure Sports Medicine, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9958-2511","authenticated-orcid":false,"given":"Kay","family":"Cooper","sequence":"additional","affiliation":[{"name":"School of Health, Robert Gordon University, Aberdeen, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0665-1835","authenticated-orcid":false,"given":"Rodrigo","family":"Rabello","sequence":"additional","affiliation":[{"name":"Sports and Exercise Medicine, Queen Mary University of London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"D2P Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"54368","reference":[{"key":"2026041314001367000_2026.04.09.26350486v1.1","unstructured":"World Health Organization. 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