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Here, we identify a continuous lymphatic circuit that sustains stem-like CD8\n                  <jats:sup>+<\/jats:sup>\n                  T cells. Using photoconversion to fate-map intratumoral T cells we demonstrate that effector cells exit the tumor microenvironment and migrate back to the draining LN. These tumor-specific, migratory effector T cells avoid chronic antigen stimulation, re-express the transcription factor associated with self-renewal, TCF1, and enter a stem-like state in the LN. Antigen presentation in LNs by dendritic cells drives their proliferation thereby inflating the LN stem-like population. Consequently, maintenance of stem-like T cells and ICB response depends on constitutive lymphatic transport, while LN metastasis compromises the stem-like niche, diminishing ICB response. We, therefore, define a continuous, peripheral lymphatic circuit that recycles tumor-experienced effector T cells to fuel durable, systemic immune surveillance.\n                <\/jats:p>","DOI":"10.64898\/2026.04.30.721705","type":"posted-content","created":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T20:25:17Z","timestamp":1778012717000},"source":"Crossref","is-referenced-by-count":3,"title":["Lymphatic egress recycles tumor-experienced effector CD8 T cells to sustain immune surveillance"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6420-2934","authenticated-orcid":false,"given":"Ines","family":"Delclaux","sequence":"first","affiliation":[{"name":"Ronald O. 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