{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"bioRxiv"}],"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T20:59:05Z","timestamp":1781816345596,"version":"3.54.5"},"posted":{"date-parts":[[2026,6,10]]},"group-title":"Biochemistry","reference-count":164,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:00:00Z","timestamp":1781049600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.biorxiv.org\/about\/FAQ#license"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"crossref","award":["1R35GM153494"],"award-info":[{"award-number":["1R35GM153494"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"crossref","award":["R01AI186337"],"award-info":[{"award-number":["R01AI186337"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"crossref","award":["R01AG078925"],"award-info":[{"award-number":["R01AG078925"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Science Foundation","award":["2150863"],"award-info":[{"award-number":["2150863"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2026,6,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                <jats:p>\n                  Human selenoprotein S (selenos) is part of the integrated cellular stress response and linked to protein quality control and signaling pathways. Consequently, genetic polymorphisms of selenos are associated with increased risk for diabetes, dyslipidemia, and cardiovascular diseases. Determining the specific roles of selenos in these cellular pathways and diseases has been challenging, as selenos associates with a wide range of protein complexes. Thus, to map the cellular functions of selenos and uncover their interconnections, we used affinity purification and\n                  <jats:italic>in vivo<\/jats:italic>\n                  crosslinking to stabilize transient protein interactions, followed by proteomics to record the resulting selenos interactome. Through mapping of selenos protein partners, we found evidence that selenos associates with complexes responsible for the insertion of membrane proteins into the ER bilayer and their connected quality control components. Furthermore, selenos is also part of metabolic, trafficking, and mitochondrial pathways. Notably, proteins involved in translation preferentially associate with selenos when its C-terminal intrinsically disordered segment containing the redox-active motif is accessible. Together, these results identify the C-terminal redox loop of selenos as a central interaction hub connecting translation with ER membrane protein biogenesis and quality control.\n                <\/jats:p>","DOI":"10.64898\/2026.06.08.725543","type":"posted-content","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T01:35:21Z","timestamp":1781141721000},"source":"Crossref","is-referenced-by-count":0,"title":["Selenoprotein S plays a role in translation and membrane protein biogenesis"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7342-7361","authenticated-orcid":false,"given":"Farid","family":"Ghelichkhani","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1703-6539","authenticated-orcid":false,"given":"Mariia A.","family":"Kapitonova","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6512-013X","authenticated-orcid":false,"given":"Atinuke","family":"Odunsi","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3895-055X","authenticated-orcid":false,"given":"Erfan","family":"Rahmani","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, University of Delaware, Newark, DE, 19713 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5845-5724","authenticated-orcid":false,"given":"Omar G. Rosas","family":"Bringas","sequence":"additional","affiliation":[{"name":"Laboratory of Cellular and Structural Biology, The Rockefeller University, New York City, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4012-3930","authenticated-orcid":false,"given":"Mohammed Hanzala","family":"Kaniyar","sequence":"additional","affiliation":[{"name":"Laboratory of Cellular and Structural Biology, The Rockefeller University, New York City, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6307-7713","authenticated-orcid":false,"given":"John","family":"LaCava","sequence":"additional","affiliation":[{"name":"Laboratory of Cellular and Structural Biology, The Rockefeller University, New York City, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4902-0777","authenticated-orcid":false,"given":"Sharon","family":"Rozovsky","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"54368","reference":[{"key":"2026061813350515000_2026.06.08.725543v2.1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M116.756155"},{"key":"2026061813350515000_2026.06.08.725543v2.2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1083516"},{"key":"2026061813350515000_2026.06.08.725543v2.3","doi-asserted-by":"crossref","unstructured":"Hatfield, D. L. ; Berry, M. J. ; Gladyshev, V . N. Selenium: Its Molecular Biology and Role in Human Health; Springer, 2006.","DOI":"10.1007\/0-387-33827-6"},{"key":"2026061813350515000_2026.06.08.725543v2.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2010.02.032"},{"key":"2026061813350515000_2026.06.08.725543v2.5","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-819460-7.00135-3"},{"key":"2026061813350515000_2026.06.08.725543v2.6","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.6b00031"},{"key":"2026061813350515000_2026.06.08.725543v2.7","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2015.6388"},{"key":"2026061813350515000_2026.06.08.725543v2.8","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00244.2017"},{"key":"2026061813350515000_2026.06.08.725543v2.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2022.109427"},{"key":"2026061813350515000_2026.06.08.725543v2.10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.5c00062"},{"key":"2026061813350515000_2026.06.08.725543v2.11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0062102"},{"key":"2026061813350515000_2026.06.08.725543v2.12","doi-asserted-by":"publisher","DOI":"10.1038\/nature02656"},{"key":"2026061813350515000_2026.06.08.725543v2.13","doi-asserted-by":"publisher","DOI":"10.1038\/celldisc.2017.45"},{"key":"2026061813350515000_2026.06.08.725543v2.14","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.534529"},{"key":"2026061813350515000_2026.06.08.725543v2.15","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M034603"},{"key":"2026061813350515000_2026.06.08.725543v2.16","doi-asserted-by":"publisher","DOI":"10.1530\/joe-19-0292"},{"key":"2026061813350515000_2026.06.08.725543v2.17","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-022-04716-w"},{"key":"2026061813350515000_2026.06.08.725543v2.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2021.106111"},{"key":"2026061813350515000_2026.06.08.725543v2.19","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2021.102289"},{"key":"2026061813350515000_2026.06.08.725543v2.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2021.112856"},{"key":"2026061813350515000_2026.06.08.725543v2.21","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-90126-5"},{"key":"2026061813350515000_2026.06.08.725543v2.22","doi-asserted-by":"publisher","DOI":"10.1021\/bi400741c"},{"key":"2026061813350515000_2026.06.08.725543v2.23","doi-asserted-by":"publisher","DOI":"10.1021\/bi4001358"},{"key":"2026061813350515000_2026.06.08.725543v2.24","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msz218"},{"key":"2026061813350515000_2026.06.08.725543v2.25","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03819-2"},{"key":"2026061813350515000_2026.06.08.725543v2.26","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-023-00673-0"},{"key":"2026061813350515000_2026.06.08.725543v2.27","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkad1058"},{"key":"2026061813350515000_2026.06.08.725543v2.28","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20140076"},{"key":"2026061813350515000_2026.06.08.725543v2.29","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2383"},{"key":"2026061813350515000_2026.06.08.725543v2.30","doi-asserted-by":"publisher","DOI":"10.7150\/thno.97005"},{"key":"2026061813350515000_2026.06.08.725543v2.31","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07487-w"},{"key":"2026061813350515000_2026.06.08.725543v2.32","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0505006102"},{"key":"2026061813350515000_2026.06.08.725543v2.33","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.571372"},{"key":"2026061813350515000_2026.06.08.725543v2.34","doi-asserted-by":"publisher","DOI":"10.2144\/000114262"},{"key":"2026061813350515000_2026.06.08.725543v2.35","doi-asserted-by":"publisher","DOI":"10.1515\/BC.2007.138"},{"key":"2026061813350515000_2026.06.08.725543v2.36","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2014.02.001"},{"key":"2026061813350515000_2026.06.08.725543v2.37","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3395"},{"key":"2026061813350515000_2026.06.08.725543v2.38","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201500526"},{"key":"2026061813350515000_2026.06.08.725543v2.39","doi-asserted-by":"publisher","DOI":"10.1186\/s12014-025-09572-2"},{"key":"2026061813350515000_2026.06.08.725543v2.40","doi-asserted-by":"publisher","DOI":"10.1038\/celldisc.2017.45"},{"key":"2026061813350515000_2026.06.08.725543v2.41","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M116.061036"},{"key":"2026061813350515000_2026.06.08.725543v2.42","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E23-06-0237"},{"key":"2026061813350515000_2026.06.08.725543v2.43","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.644"},{"key":"2026061813350515000_2026.06.08.725543v2.44","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.9b00177"},{"key":"2026061813350515000_2026.06.08.725543v2.45","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05330-8"},{"key":"2026061813350515000_2026.06.08.725543v2.46","doi-asserted-by":"publisher","DOI":"10.1038\/s41594-024-01296-5"},{"key":"2026061813350515000_2026.06.08.725543v2.47","doi-asserted-by":"publisher","DOI":"10.1038\/s41594-025-01691-6"},{"key":"2026061813350515000_2026.06.08.725543v2.48","doi-asserted-by":"publisher","DOI":"10.1126\/science.aao3099"},{"key":"2026061813350515000_2026.06.08.725543v2.49","doi-asserted-by":"publisher","DOI":"10.1038\/s41594-023-01120-6"},{"key":"2026061813350515000_2026.06.08.725543v2.50","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-032620-104553"},{"key":"2026061813350515000_2026.06.08.725543v2.51","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202302266r"},{"key":"2026061813350515000_2026.06.08.725543v2.52","doi-asserted-by":"publisher","DOI":"10.1101\/2025.03.10.642408"},{"key":"2026061813350515000_2026.06.08.725543v2.53","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2025.112096"},{"key":"2026061813350515000_2026.06.08.725543v2.54","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1001969"},{"key":"2026061813350515000_2026.06.08.725543v2.55","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.57887"},{"key":"2026061813350515000_2026.06.08.725543v2.56","doi-asserted-by":"publisher","DOI":"10.18632\/aging.205660"},{"key":"2026061813350515000_2026.06.08.725543v2.57","doi-asserted-by":"publisher","DOI":"10.3390\/cells10071737"},{"key":"2026061813350515000_2026.06.08.725543v2.58","doi-asserted-by":"publisher","DOI":"10.3390\/biom14101218"},{"key":"2026061813350515000_2026.06.08.725543v2.59","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03592-2"},{"key":"2026061813350515000_2026.06.08.725543v2.60","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2024.08.005"},{"key":"2026061813350515000_2026.06.08.725543v2.61","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.310920"},{"key":"2026061813350515000_2026.06.08.725543v2.62","doi-asserted-by":"publisher","DOI":"10.1111\/febs.15548"},{"key":"2026061813350515000_2026.06.08.725543v2.63","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2018.06.009"},{"key":"2026061813350515000_2026.06.08.725543v2.64","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a041248"},{"key":"2026061813350515000_2026.06.08.725543v2.65","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2021.05.004"},{"key":"2026061813350515000_2026.06.08.725543v2.66","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3001950"},{"key":"2026061813350515000_2026.06.08.725543v2.67","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20236074"},{"key":"2026061813350515000_2026.06.08.725543v2.68","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwad053"},{"key":"2026061813350515000_2026.06.08.725543v2.69","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-025-00855-y"},{"key":"2026061813350515000_2026.06.08.725543v2.70","doi-asserted-by":"publisher","DOI":"10.1101\/2024.05.12.593735"},{"key":"2026061813350515000_2026.06.08.725543v2.71","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241814166"},{"key":"2026061813350515000_2026.06.08.725543v2.72","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.56889"},{"key":"2026061813350515000_2026.06.08.725543v2.73","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-021-00413-2"},{"key":"2026061813350515000_2026.06.08.725543v2.74","doi-asserted-by":"publisher","DOI":"10.1038\/s41594-020-00541-x"},{"key":"2026061813350515000_2026.06.08.725543v2.75","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222312757"},{"key":"2026061813350515000_2026.06.08.725543v2.76","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05336-2"},{"key":"2026061813350515000_2026.06.08.725543v2.77","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.12.006"},{"key":"2026061813350515000_2026.06.08.725543v2.78","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2014.06.024"},{"key":"2026061813350515000_2026.06.08.725543v2.79","unstructured":"Pauwels, E. ; Shewakramani, N. R. ; Wijngaert, B. D. ; Camps, A. ; Provinciael, B. ; Stroobants, J. ; Kalies, K.-U. ; Hartmann, E. ; Maes, P. ; Vermeire, K. ; Das, K . Structural Insights into TRAP Association with Ribosome-Sec61 Complex and Translocon Inhibition by a CADA Derivative. SCIENCE ADVANCES."},{"key":"2026061813350515000_2026.06.08.725543v2.80","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.09.047"},{"key":"2026061813350515000_2026.06.08.725543v2.81","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201488208"},{"key":"2026061813350515000_2026.06.08.725543v2.82","doi-asserted-by":"publisher","DOI":"10.1126\/science.abc5809"},{"key":"2026061813350515000_2026.06.08.725543v2.83","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adt1346"},{"key":"2026061813350515000_2026.06.08.725543v2.84","doi-asserted-by":"publisher","DOI":"10.3390\/cells11182925"},{"key":"2026061813350515000_2026.06.08.725543v2.85","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-65357-z"},{"key":"2026061813350515000_2026.06.08.725543v2.86","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.08.082"},{"key":"2026061813350515000_2026.06.08.725543v2.87","doi-asserted-by":"publisher","DOI":"10.1126\/science.adp0787"},{"key":"2026061813350515000_2026.06.08.725543v2.88","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2015.01.133"},{"key":"2026061813350515000_2026.06.08.725543v2.89","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2017.03.060"},{"key":"2026061813350515000_2026.06.08.725543v2.90","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-23284-8"},{"key":"2026061813350515000_2026.06.08.725543v2.91","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.122.061557"},{"key":"2026061813350515000_2026.06.08.725543v2.92","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.680215"},{"key":"2026061813350515000_2026.06.08.725543v2.93","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-023-00633-8"},{"key":"2026061813350515000_2026.06.08.725543v2.94","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-26370-0"},{"key":"2026061813350515000_2026.06.08.725543v2.95","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2021.102758"},{"key":"2026061813350515000_2026.06.08.725543v2.96","doi-asserted-by":"publisher","DOI":"10.1038\/s44319-024-00205-7"},{"key":"2026061813350515000_2026.06.08.725543v2.97","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.795912"},{"key":"2026061813350515000_2026.06.08.725543v2.98","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2022.07.006"},{"key":"2026061813350515000_2026.06.08.725543v2.99","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2023.07.026"},{"key":"2026061813350515000_2026.06.08.725543v2.100","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.260995"},{"key":"2026061813350515000_2026.06.08.725543v2.101","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-025-08878-3"},{"key":"2026061813350515000_2026.06.08.725543v2.102","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.2111"},{"key":"2026061813350515000_2026.06.08.725543v2.103","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-025-08880-5"},{"key":"2026061813350515000_2026.06.08.725543v2.104","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2017.10.028"},{"key":"2026061813350515000_2026.06.08.725543v2.105","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2023.1142989"},{"key":"2026061813350515000_2026.06.08.725543v2.106","unstructured":"Braxton, J. R. ; Southworth, D. R. Structural Insights of the P97\/VCP AAA+ ATPase: How Adapter Interactions Coordinate Diverse Cellular Functionality."},{"key":"2026061813350515000_2026.06.08.725543v2.107","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.RA117.000471"},{"key":"2026061813350515000_2026.06.08.725543v2.108","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.284794"},{"key":"2026061813350515000_2026.06.08.725543v2.109","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3001474"},{"key":"2026061813350515000_2026.06.08.725543v2.110","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.044685"},{"key":"2026061813350515000_2026.06.08.725543v2.111","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2427250122"},{"key":"2026061813350515000_2026.06.08.725543v2.112","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2024.1268013"},{"key":"2026061813350515000_2026.06.08.725543v2.113","doi-asserted-by":"publisher","DOI":"10.15252\/embr.202255175"},{"key":"2026061813350515000_2026.06.08.725543v2.114","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1213738110"},{"key":"2026061813350515000_2026.06.08.725543v2.115","doi-asserted-by":"publisher","DOI":"10.15252\/embr.202254859"},{"key":"2026061813350515000_2026.06.08.725543v2.116","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-53558-x"},{"key":"2026061813350515000_2026.06.08.725543v2.117","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.202409024"},{"key":"2026061813350515000_2026.06.08.725543v2.118","doi-asserted-by":"publisher","DOI":"10.1101\/2024.12.12.628015"},{"key":"2026061813350515000_2026.06.08.725543v2.119","doi-asserted-by":"publisher","DOI":"10.1038\/s41594-023-01126-0"},{"key":"2026061813350515000_2026.06.08.725543v2.120","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-20796-8"},{"key":"2026061813350515000_2026.06.08.725543v2.121","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2023.01.016"},{"key":"2026061813350515000_2026.06.08.725543v2.122","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-62073-6"},{"key":"2026061813350515000_2026.06.08.725543v2.123","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200903024"},{"key":"2026061813350515000_2026.06.08.725543v2.124","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.257790"},{"key":"2026061813350515000_2026.06.08.725543v2.125","doi-asserted-by":"publisher","DOI":"10.3109\/07388551.2012.732031"},{"key":"2026061813350515000_2026.06.08.725543v2.126","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2022.102654"},{"key":"2026061813350515000_2026.06.08.725543v2.127","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-025-01620-1"},{"key":"2026061813350515000_2026.06.08.725543v2.128","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2512430122"},{"key":"2026061813350515000_2026.06.08.725543v2.129","doi-asserted-by":"publisher","DOI":"10.3390\/cells7120238"},{"key":"2026061813350515000_2026.06.08.725543v2.130","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.19.5.3435"},{"key":"2026061813350515000_2026.06.08.725543v2.131","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2023.09.001"},{"key":"2026061813350515000_2026.06.08.725543v2.132","doi-asserted-by":"publisher","DOI":"10.1126\/science.adu6445"},{"key":"2026061813350515000_2026.06.08.725543v2.133","doi-asserted-by":"publisher","DOI":"10.1002\/1873-3468.14089"},{"key":"2026061813350515000_2026.06.08.725543v2.134","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2024.107530"},{"key":"2026061813350515000_2026.06.08.725543v2.135","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa1011"},{"key":"2026061813350515000_2026.06.08.725543v2.136","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25137261"},{"key":"2026061813350515000_2026.06.08.725543v2.137","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2018.07.005"},{"key":"2026061813350515000_2026.06.08.725543v2.138","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2023.11.040"},{"key":"2026061813350515000_2026.06.08.725543v2.139","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-025-00864-x"},{"key":"2026061813350515000_2026.06.08.725543v2.140","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.24463"},{"key":"2026061813350515000_2026.06.08.725543v2.141","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09234-6"},{"key":"2026061813350515000_2026.06.08.725543v2.142","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-48251-y"},{"key":"2026061813350515000_2026.06.08.725543v2.143","doi-asserted-by":"publisher","DOI":"10.3390\/epigenomes4020007"},{"key":"2026061813350515000_2026.06.08.725543v2.144","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.431270"},{"key":"2026061813350515000_2026.06.08.725543v2.145","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20211699"},{"key":"2026061813350515000_2026.06.08.725543v2.146","doi-asserted-by":"publisher","DOI":"10.1042\/BST20221035"},{"key":"2026061813350515000_2026.06.08.725543v2.147","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcpro.2023.100640"},{"key":"2026061813350515000_2026.06.08.725543v2.148","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.215871"},{"key":"2026061813350515000_2026.06.08.725543v2.149","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21176146"},{"key":"2026061813350515000_2026.06.08.725543v2.150","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cellbio-120420-015303"},{"key":"2026061813350515000_2026.06.08.725543v2.151","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.988014"},{"key":"2026061813350515000_2026.06.08.725543v2.152","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagrm.2017.11.006"},{"key":"2026061813350515000_2026.06.08.725543v2.153","doi-asserted-by":"publisher","DOI":"10.1002\/bies.201900009"},{"key":"2026061813350515000_2026.06.08.725543v2.154","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-025-01765-z"},{"key":"2026061813350515000_2026.06.08.725543v2.155","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2019.08.030"},{"key":"2026061813350515000_2026.06.08.725543v2.156","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0194887"},{"key":"2026061813350515000_2026.06.08.725543v2.157","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1322"},{"key":"2026061813350515000_2026.06.08.725543v2.158","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.0c02564"},{"key":"2026061813350515000_2026.06.08.725543v2.159","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btg287"},{"key":"2026061813350515000_2026.06.08.725543v2.160","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa498"},{"key":"2026061813350515000_2026.06.08.725543v2.161","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/18.suppl_1.S96"},{"key":"2026061813350515000_2026.06.08.725543v2.162","doi-asserted-by":"publisher","DOI":"10.21105\/joss.05184"},{"key":"2026061813350515000_2026.06.08.725543v2.163","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv007"},{"key":"2026061813350515000_2026.06.08.725543v2.164","doi-asserted-by":"publisher","DOI":"10.1126\/science.aal3321"}],"container-title":[],"original-title":[],"link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.64898\/2026.06.08.725543","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T20:35:17Z","timestamp":1781814917000},"score":1,"resource":{"primary":{"URL":"http:\/\/biorxiv.org\/lookup\/doi\/10.64898\/2026.06.08.725543"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,10]]},"references-count":164,"URL":"https:\/\/doi.org\/10.64898\/2026.06.08.725543","relation":{},"subject":[],"published":{"date-parts":[[2026,6,10]]},"subtype":"preprint"}}