{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"medRxiv"}],"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T15:46:45Z","timestamp":1782316005919,"version":"3.54.5"},"posted":{"date-parts":[[2026,6,22]]},"group-title":"Epidemiology","reference-count":45,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of North Carolina Office of Research"},{"DOI":"10.13039\/100000002","name":"The National Institutes of Health","doi-asserted-by":"crossref","award":["T32AI070114; R01AI129812; R01AI132547"],"award-info":[{"award-number":["T32AI070114; R01AI129812; R01AI132547"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2026,6,22]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                <jats:p>Dengue (DENV) and chikungunya (CHIKV) are understudied in the Democratic Republic of the Congo (DRC) and across Africa despite evidence of transmission. We measured DENV and CHIKV IgG seroprevalences in Kinshasa Province, DRC, by antigen-capture ELISA, using dried blood spots from 2021. Force of infection (FOI) was estimated from age-stratified seroprevalences using Bayesian catalytic modeling. Among 1,250 participants, DENV IgG seroprevalence was 38.1% (95% CI: 34.5%-41.8%), increasing with age, and highest within peri-urban Kimpoko sites (54.9%). CHIKV IgG seroprevalence was 24.2% (95% CI: 21.1%-27.6%), increasing with age and comparable between peri-urban Kimpoko and rural Bu, with few seropositives in the city-center. DENV-CHIKV IgG co-occurrence was detected in 12.8% of participants. Time-varying FOI models provided best fit to age-stratified seroprevalences, with spatial variation detected. Sustained DENV and CHIKV circulation across Kinshasa highlights an under-appreciated transmission risk and underscores the need for strengthened arboviral surveillance in the DRC and surrounding region.<\/jats:p>","DOI":"10.64898\/2026.06.11.26355423","type":"posted-content","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T15:10:20Z","timestamp":1782141020000},"source":"Crossref","is-referenced-by-count":0,"title":["Dengue and chikungunya virus transmission in Kinshasa, Democratic Republic of the Congo"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7259-1514","authenticated-orcid":false,"given":"Rachel","family":"Sendor","sequence":"first","affiliation":[{"name":"University of North Carolina at Chapel Hill, Gillings School of Global Public Health, Chapel Hill, North Carolina, United States of 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Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9741-8109","authenticated-orcid":false,"given":"Justin","family":"Lessler","sequence":"additional","affiliation":[{"name":"University of North Carolina at Chapel Hill, Gillings School of Global Public Health, Chapel Hill, North Carolina, United States of America"},{"name":"University of North Carolina at Chapel Hill, Carolina Population Center, Chapel Hill, North Carolina, United States of America"},{"name":"Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel O.","family":"Espinoza","sequence":"additional","affiliation":[{"name":"Emory University, Division of Infectious Diseases, Atlanta, Georgia, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izabella N.","family":"Castillo","sequence":"additional","affiliation":[{"name":"University of North Carolina at Chapel Hill, Department of Microbiology and Immunology, Chapel Hill, North Carolina, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabien","family":"Vulu","sequence":"additional","affiliation":[{"name":"University of Kinshasa, Department of Tropical Medicine, Facult\u00e9 de M\u00e9decine, Kinshasa, Democratic Republic of the Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nono","family":"Mvuama","sequence":"additional","affiliation":[{"name":"University of Kinshasa, Ecole de Sant\u00e9 Publique, Facult\u00e9 de M\u00e9decine, Kinshasa, Democratic Republic of the Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph A.","family":"Bala","sequence":"additional","affiliation":[{"name":"University of Kinshasa, Ecole de Sant\u00e9 Publique, Facult\u00e9 de M\u00e9decine, Kinshasa, Democratic 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