{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"medRxiv"}],"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:38:15Z","timestamp":1792640295667,"version":"4.5.0"},"posted":{"date-parts":[[2026,7,28]]},"group-title":"Neurology","reference-count":10,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"U.S. Department of Defense Congressionally Directed Medical Research Programs","award":["HT9425-24-1-0066"],"award-info":[{"award-number":["HT9425-24-1-0066"]}]},{"DOI":"10.13039\/100007338","name":"Foundation for Barnes-Jewish Hospital","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007338","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Washington University\/BJC HealthCare Big Ideas Competition"},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"crossref","award":["1K23AR082986-01A1"],"award-info":[{"award-number":["1K23AR082986-01A1"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2026,7,28]]},"abstract":"<jats:title>Summary<\/jats:title>\n                <jats:p>Cervical spondylotic myelopathy (CSM) is the most common cause of nontraumatic spinal cord dysfunction in adults and is an increasingly important source of disability as populations age. Gabapentin is widely prescribed for neuropathic pain and may therefore be used for symptoms related to known or undiagnosed CSM. However, there is sparse evidence related specifically to gabapentin\u2019s use for CSM-related pain. We investigate gabapentin use and trends over time in patients with CSM compared to matched controls. We observed that gabapentin prescriptions were higher in CSM patients compared to controls across two multi-hospital datasets. These results highlight the need for further research into pharmacologic treatment for chronic pain in CSM.<\/jats:p>","DOI":"10.64898\/2026.07.27.26358977","type":"posted-content","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T23:10:18Z","timestamp":1785280218000},"source":"Crossref","is-referenced-by-count":1,"title":["Patterns of Gabapentin Use in Patients With Cervical Spondylotic Myelopathy"],"prefix":"10.64898","author":[{"given":"Benjamin C.","family":"Warner","sequence":"first","affiliation":[{"name":"Department of Computer Science & Engineering, Washington University in St. Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faraz","family":"Arkam","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Washington University School of Medicine in St. Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salim","family":"Yakdan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Washington University School of Medicine in St. Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Hammo","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Washington University School of Medicine in St. Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilson Z.","family":"Ray","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Washington University School of Medicine in St. Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Wilcox","sequence":"additional","affiliation":[{"name":"Institute for Informatics, Washington University School of Medicine in St. Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randi","family":"Foraker","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Biostatistics, and Medical Epidemiology, University of Missouri School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyang","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Computer Science & Engineering, Washington University in St. Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob K.","family":"Greenberg","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Washington University School of Medicine in St. Louis"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"54368","reference":[{"key":"2026073103500920000_2026.07.27.26358977v1.1","doi-asserted-by":"publisher","DOI":"10.3171\/2025.11.SPINE25662"},{"key":"2026073103500920000_2026.07.27.26358977v1.2","doi-asserted-by":"publisher","DOI":"10.1177\/21925682221124098"},{"issue":"2","key":"2026073103500920000_2026.07.27.26358977v1.3","doi-asserted-by":"crossref","first-page":"375","DOI":"10.14245\/ns.2448140.070","article-title":"Pharmacological treatment of degenerative cervical myelopathy: a critical review of current evidence","volume":"21","year":"2024","journal-title":"Neurospine"},{"key":"2026073103500920000_2026.07.27.26358977v1.4","unstructured":"CADTH. Gabapentin for Adults with Neuropathic Pain: A Review of the Clinical Efficacy and Safety. Canadian Agency for Drugs and Technologies in Health; 2015."},{"issue":"7","key":"2026073103500920000_2026.07.27.26358977v1.5","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1097\/j.pain.0000000000000554","article-title":"A randomized controlled trial of gabapentin for chronic low back pain with and without a radiating component","volume":"157","year":"2016","journal-title":"Pain"},{"key":"2026073103500920000_2026.07.27.26358977v1.6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002369"},{"key":"2026073103500920000_2026.07.27.26358977v1.7","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/s41746-026-02337-7","article-title":"Clinically-guided models or foundation models? Predicting cervical spondylotic myelopathy from electronic health records","volume":"9","year":"2026","journal-title":"npj Digit Med"},{"key":"2026073103500920000_2026.07.27.26358977v1.8","unstructured":"Steinberg E , Fries JA , Xu Y , Shah N. MOTOR: A Time-to-Event Foundation Model For Structured Medical Records. In: The Twelfth International Conference on Learning Representations. 2024. https:\/\/openreview.net\/forum?id=NialiwI2V6"},{"issue":"7","key":"2026073103500920000_2026.07.27.26358977v1.9","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/S1474-4422(19)30168-1","article-title":"A focus on patient outcomes in cervical myelopathy","volume":"18","author":"The Lancet Neurology","year":"2019","journal-title":"Lancet Neurol"},{"key":"2026073103500920000_2026.07.27.26358977v1.10","doi-asserted-by":"publisher","DOI":"10.3171\/2021.7.SPINE21590"}],"container-title":[],"original-title":[],"link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.64898\/2026.07.27.26358977","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T10:50:18Z","timestamp":1785495018000},"score":1,"resource":{"primary":{"URL":"http:\/\/medrxiv.org\/lookup\/doi\/10.64898\/2026.07.27.26358977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,28]]},"references-count":10,"URL":"https:\/\/doi.org\/10.64898\/2026.07.27.26358977","relation":{},"subject":[],"published":{"date-parts":[[2026,7,28]]},"subtype":"preprint"}}