{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"bioRxiv"}],"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:18:30Z","timestamp":1792790310275,"version":"4.5.0"},"posted":{"date-parts":[[2026,9,17]]},"group-title":"Bioengineering","reference-count":67,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"award":["1U19AI181881"],"award-info":[{"award-number":["1U19AI181881"]}],"id":[{"id":"https:\/\/ror.org\/043z4tv69","id-type":"ROR","asserted-by":"publisher"}]},{"award":["DP1AI158186"],"award-info":[{"award-number":["DP1AI158186"]}],"id":[{"id":"https:\/\/ror.org\/043z4tv69","id-type":"ROR","asserted-by":"publisher"}]},{"award":["75N93022C00036"],"award-info":[{"award-number":["75N93022C00036"]}],"id":[{"id":"https:\/\/ror.org\/043z4tv69","id-type":"ROR","asserted-by":"publisher"}]},{"name":"Burroughs Wellcome Fund","id":[{"id":"https:\/\/ror.org\/01d35cw23","id-type":"ROR","asserted-by":"crossref"}]},{"name":"National Institutes of Health","award":["AI181930"],"award-info":[{"award-number":["AI181930"]}]},{"name":"National Institutes of Health","award":["AI142764"],"award-info":[{"award-number":["AI142764"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2026,9,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                <jats:p>\n                  The prototype members of the genus\n                  <jats:italic>Henipavirus,<\/jats:italic>\n                  Nipah virus (NiV) and Hendra virus (HeV), cause recurrent zoonotic spillovers with case fatality rates ranging from 40-90% in humans. Currently, there are no approved vaccines or therapeutics for use in humans. Neutralizing antibodies targeting the NiV\/HeV F-or G-glycoproteins protect animals from lethal challenge and are a main correlate of protection. However, antibody-based formulations are expensive, typically requiring hospital admission for administration and cold-chain for storage and transportation. To address the lack of shelf-stable clinical countermeasures, we computationally designed thermostable miniproteins that cross-react with subnanomolar affinities with both NiV and HeV F and G glycoproteins and inhibit viral entry\n                  <jats:italic>in vitro<\/jats:italic>\n                  with potencies comparable to lead antibodies. Oligomerized forms of these miniproteins have enhanced potency relative to their monomeric building blocks and increase the barrier for emergence of escape mutants, establishing them as promising preclinical candidates against these deadly viruses.\n                <\/jats:p>","DOI":"10.64898\/2026.09.14.751546","type":"posted-content","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T11:35:23Z","timestamp":1789644923000},"source":"Crossref","is-referenced-by-count":0,"title":["Computational design of potent, broadly neutralizing anti-Nipah virus and Hendra virus miniproteins"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0479-0367","authenticated-orcid":false,"given":"Jeremiah N.","family":"Sims","sequence":"first","affiliation":[{"name":"Institute for Protein Design, University of Washington, Seattle, WA 98105, USA"},{"name":"Molecular & Cellular Biology Graduate Program, University of Washington, Seattle, WA 98105, USA"},{"name":"Medical Scientist Training Program, University of Washington, Seattle, WA 98105, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4416-0417","authenticated-orcid":false,"given":"Risako","family":"Gen","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Washington, Seattle, WA 98195, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0007-2226","authenticated-orcid":false,"given":"Kaitlin","family":"Sprouse","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute, University of Washington, Seattle, WA 98105, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Jun","family":"Park","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute, University of Washington, Seattle, WA 98105, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8989-0422","authenticated-orcid":false,"given":"Zhaoqian","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Washington, Seattle, WA 98195, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moushimi","family":"Amaya","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7287-1219","authenticated-orcid":false,"given":"Alka","family":"Jays","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA"},{"name":"Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan B.","family":"Larsen","sequence":"additional","affiliation":[{"name":"Basic Sciences Division and Computational Biology Program, Fred Hutch Cancer Center, Seattle, WA 98109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron","family":"Stewart","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Washington, Seattle, WA 98195, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack T.","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Washington, Seattle, WA 98195, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6463-1595","authenticated-orcid":false,"given":"Robert","family":"Ragotte","sequence":"additional","affiliation":[{"name":"Institute for Protein Design, University of Washington, Seattle, WA 98105, USA"},{"name":"Department of Biochemistry, University of Washington, Seattle, WA 98195, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2630-7487","authenticated-orcid":false,"given":"Rashmi","family":"Ravichandran","sequence":"additional","affiliation":[{"name":"Institute for Protein Design, University of Washington, Seattle, WA 98105, USA"},{"name":"Department of Biochemistry, University of Washington, Seattle, WA 98195, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4974-0410","authenticated-orcid":false,"given":"Garrett","family":"Ruth","sequence":"additional","affiliation":[{"name":"Institute for Protein Design, University of Washington, Seattle, WA 98105, USA"},{"name":"Department of Biochemistry, University of Washington, Seattle, WA 98195, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5559-7578","authenticated-orcid":false,"given":"Xinting","family":"Li","sequence":"additional","affiliation":[{"name":"Institute for Protein Design, University of Washington, Seattle, WA 98105, USA"},{"name":"Department of Biochemistry, University of Washington, Seattle, WA 98195, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2560-8907","authenticated-orcid":false,"given":"Dionne","family":"Vafeados","sequence":"additional","affiliation":[{"name":"Institute for Protein Design, University of Washington, Seattle, WA 98105, USA"},{"name":"Molecular & Cellular Biology Graduate Program, University of Washington, Seattle, WA 98105, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1267-3408","authenticated-orcid":false,"given":"Jesse D.","family":"Bloom","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute, University of Washington, Seattle, WA 98105, USA"},{"name":"Basic Sciences Division and Computational Biology Program, Fred Hutch Cancer Center, Seattle, WA 98109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5382-0510","authenticated-orcid":false,"given":"Christopher","family":"Broder","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6019-8675","authenticated-orcid":false,"given":"David","family":"Veesler","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Washington, Seattle, WA 98195, USA"},{"name":"Howard Hughes Medical Institute, University of Washington, Seattle, WA 98105, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7896-6217","authenticated-orcid":false,"given":"David","family":"Baker","sequence":"additional","affiliation":[{"name":"Institute for Protein Design, University of Washington, Seattle, WA 98105, USA"},{"name":"Department of Biochemistry, University of Washington, Seattle, WA 98195, USA"},{"name":"Howard Hughes Medical Institute, University of Washington, Seattle, WA 98105, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"54368","reference":[{"issue":"11","key":"2026092104150914000_2026.09.14.751546v1.1","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1038\/nsmb.3115","article-title":"\u201cPrivateer: Software for the Conformational Validation of Carbohydrate Structures.\u201d","volume":"22","year":"2015","journal-title":"Nature Structural S Molecular Biology"},{"issue":"5","key":"2026092104150914000_2026.09.14.751546v1.2","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.3390\/v15051077","article-title":"A Recombinant Chimeric Cedar Virus-Based Surrogate Neutralization Assay Platform for Pathogenic Henipaviruses","volume":"15","year":"2023","journal-title":"Viruses"},{"key":"2026092104150914000_2026.09.14.751546v1.3","doi-asserted-by":"publisher","DOI":"10.3201\/eid2803.211245"},{"key":"2026092104150914000_2026.09.14.751546v1.4","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1912503116"},{"issue":"10","key":"2026092104150914000_2026.09.14.751546v1.5","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1038\/nmeth.3541","article-title":"EMRinger: Side Chain-Directed Model and Map Validation for 3D Cryo-Electron Microscopy","volume":"12","year":"2015","journal-title":"Nature Methods"},{"issue":"11","key":"2026092104150914000_2026.09.14.751546v1.6","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1038\/s41592-019-0575-8","article-title":"Positive-Unlabeled Convolutional Neural Networks for Particle Picking in Cryo-Electron Micrographs","volume":"16","year":"2019","journal-title":"Nature Methods"},{"key":"2026092104150914000_2026.09.14.751546v1.7","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0504887102"},{"key":"2026092104150914000_2026.09.14.751546v1.8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000642"},{"issue":"6","key":"2026092104150914000_2026.09.14.751546v1.9","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/nsmb.1435","article-title":"Structural Basis of Nipah and Hendra Virus Attachment to Their Cell-Surface Receptor Ephrin-B2","volume":"15","year":"2008","journal-title":"Nature Structural S Molecular Biology"},{"issue":"1","key":"2026092104150914000_2026.09.14.751546v1.10","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1038\/s41467-023-36995-y","article-title":"Structural Basis for Antibody Recognition of Vulnerable Epitopes on Nipah Virus F Protein","volume":"14","year":"2023","journal-title":"Nature Communications"},{"key":"2026092104150914000_2026.09.14.751546v1.11","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-04654-9"},{"issue":"6515","key":"2026092104150914000_2026.09.14.751546v1.12","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1126\/science.abd9909","article-title":"\u201cDe Novo Design of Picomolar SARS-CoV-2 Miniprotein Inhibitors.\u201d","volume":"370","year":"2020","journal-title":"Science (New York, N.Y.)"},{"issue":"7","key":"2026092104150914000_2026.09.14.751546v1.13","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.chom.2021.06.008","article-title":"Ultrapotent Miniproteins Targeting the SARS-CoV-2 Receptor-Binding Domain Protect against Infection and Disease","volume":"29","year":"2021","journal-title":"Cell Host S Microbe"},{"key":"2026092104150914000_2026.09.14.751546v1.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultramic.2013.06.004"},{"key":"2026092104150914000_2026.09.14.751546v1.15","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444909042073"},{"key":"2026092104150914000_2026.09.14.751546v1.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2023.02.001"},{"issue":"10","key":"2026092104150914000_2026.09.14.751546v1.17","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1038\/s41594-019-0308-9","article-title":"An Antibody against the F Glycoprotein Inhibits Nipah and Hendra Virus Infections","volume":"26","year":"2019","journal-title":"Nature Structural S Molecular Biology"},{"issue":"5","key":"2026092104150914000_2026.09.14.751546v1.18","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/s41594-021-00584-8","article-title":"Broadly Neutralizing Antibody Cocktails Targeting Nipah Virus and Hendra Virus Fusion Glycoproteins","volume":"28","year":"2021","journal-title":"Nature Structural S Molecular Biology"},{"key":"2026092104150914000_2026.09.14.751546v1.19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.11.023"},{"issue":"9","key":"2026092104150914000_2026.09.14.751546v1.20","doi-asserted-by":"crossref","first-page":"109628","DOI":"10.1016\/j.celrep.2021.109628","article-title":"Cooperativity Mediated by Rationally Selected Combinations of Human Monoclonal Antibodies Targeting the Henipavirus Receptor Binding Protein","volume":"36","year":"2021","journal-title":"Cell Reports"},{"issue":"Pt 4","key":"2026092104150914000_2026.09.14.751546v1.21","first-page":"486","article-title":"\u201cFeatures and Development of Coot.\u201d Acta Crystallographica. Section D","volume":"66","year":"2010","journal-title":"Biological Crystallography"},{"key":"2026092104150914000_2026.09.14.751546v1.22","doi-asserted-by":"crossref","unstructured":"Geisbert, Thomas W. , Chad E. Mire , Joan B. Geisbert , et al. 2014. \u201cTherapeutic Treatment of Nipah Virus Infection in Nonhuman Primates with a Neutralizing Human Monoclonal Antibody.\u201d Science Translational Medicine 6 (242): 242ra82.","DOI":"10.1126\/scitranslmed.3008929"},{"key":"2026092104150914000_2026.09.14.751546v1.23","doi-asserted-by":"crossref","unstructured":"Guzm\u00e1n-Sol\u00eds, Axel A. , Mohamed Ouizougun-Oubari , Olivier Escaffre , et al. 2026. \u201cA Cocktail of Human mAbs Targeting the Henipavirus Fusion and Receptor Binding Proteins Provides Cross-Species Neutralization.\u201d Science Translational Medicine 18 (853): eadw8573.","DOI":"10.1126\/scitranslmed.adw8573"},{"key":"2026092104150914000_2026.09.14.751546v1.24","doi-asserted-by":"crossref","unstructured":"Hunt, Andrew C. , James Brett Case , Young-Jun Park , et al. 2022. \u201cMultivalent Designed Proteins Neutralize SARS-CoV-2 Variants of Concern and Confer Protection against Infection in Mice.\u201d Science Translational Medicine 14 (646): eabn1252.","DOI":"10.1126\/scitranslmed.abn1252"},{"issue":"10","key":"2026092104150914000_2026.09.14.751546v1.25","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1038\/s41594-025-01598-2","article-title":"\u201cA Nanobody-Based Therapeutic Targeting Nipah Virus Limits Viral Escape.\u201d","volume":"32","year":"2025","journal-title":"Nature Structural S Molecular Biology"},{"key":"2026092104150914000_2026.09.14.751546v1.26","doi-asserted-by":"publisher","DOI":"10.1101\/2025.03.11.642517"},{"key":"2026092104150914000_2026.09.14.751546v1.27","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07215-4"},{"key":"2026092104150914000_2026.09.14.751546v1.28","doi-asserted-by":"publisher","DOI":"10.1038\/S41586-021-03819-2"},{"issue":"August","key":"2026092104150914000_2026.09.14.751546v1.29","first-page":"19","article-title":"Case Fatality Rate and Risk Factors for Nipah Virus Encephalitis: A Systematic Review and Meta-Analysis","volume":"117","year":"2019","journal-title":"Journal of Clinical Virology: The Official Publication of the Pan American Society for Clinical Virology"},{"issue":"1","key":"2026092104150914000_2026.09.14.751546v1.30","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s12985-018-0964-0","article-title":"Rescue and Characterization of Recombinant Cedar Virus, a Non-Pathogenic Henipavirus Species","volume":"15","year":"2018","journal-title":"Virology Journal"},{"key":"2026092104150914000_2026.09.14.751546v1.31","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1911773116"},{"issue":"1","key":"2026092104150914000_2026.09.14.751546v1.32","doi-asserted-by":"crossref","first-page":"4629","DOI":"10.1038\/s41467-024-48059-w","article-title":"Universal Paramyxovirus Vaccine Design by Stabilizing Regions Involved in Structural Transformation of the Fusion Protein","volume":"15","year":"2024","journal-title":"Nature Communications"},{"issue":"9","key":"2026092104150914000_2026.09.14.751546v1.33","doi-asserted-by":"crossref","first-page":"2480","DOI":"10.1016\/j.cell.2025.02.030","article-title":"Functional and Antigenic Landscape of the Nipah Virus Receptor-Binding Protein","volume":"188","year":"2025","journal-title":"Cell"},{"issue":"1","key":"2026092104150914000_2026.09.14.751546v1.34","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/s42003-025-09499-2","article-title":"The Computationally Designed TRI2-2 Miniprotein Inhibitor Protects against Multiple SARS-CoV-2 Omicron Variants","volume":"9","year":"2026","journal-title":"Communications Biology"},{"issue":"Pt 10","key":"2026092104150914000_2026.09.14.751546v1.35","first-page":"861","article-title":"\u201cMacromolecular Structure Determination Using X-Rays, Neutrons and Electrons: Recent Developments in Phenix.\u201d Acta Crystallographica. Section D","volume":"75","year":"2019","journal-title":"Structural Biology"},{"key":"2026092104150914000_2026.09.14.751546v1.36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003770"},{"key":"2026092104150914000_2026.09.14.751546v1.37","doi-asserted-by":"crossref","unstructured":"Liu, Ying , Zhenzhi Han , Chuyun Kang , et al. 2022. \u201cImportation and Circulation of Rubella Virus Lineages 1E-L2 and 2B-L2c between 2018 and 2021 in China: Virus Evolution and Spatial-Temporal Transmission Characteristics.\u201d Virus Evolution 8 (2): veac083.","DOI":"10.1093\/ve\/veac083"},{"key":"2026092104150914000_2026.09.14.751546v1.38","doi-asserted-by":"publisher","DOI":"10.1007\/82_2012_207"},{"key":"2026092104150914000_2026.09.14.751546v1.39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2005.07.007"},{"key":"2026092104150914000_2026.09.14.751546v1.40","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiz515"},{"key":"2026092104150914000_2026.09.14.751546v1.41","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(24)00262-7"},{"issue":"11","key":"2026092104150914000_2026.09.14.751546v1.42","doi-asserted-by":"crossref","first-page":"e0062123","DOI":"10.1128\/jvi.00621-23","article-title":"Sequence Basis for Selectivity of Ephrin-B2 Ligand for Eph Receptors and Pathogenic Henipavirus G Glycoproteins","volume":"97","year":"2023","journal-title":"Journal of Virology"},{"key":"2026092104150914000_2026.09.14.751546v1.43","doi-asserted-by":"publisher","DOI":"10.1101\/2023.04.26.538420"},{"key":"2026092104150914000_2026.09.14.751546v1.44","doi-asserted-by":"publisher","DOI":"10.1038\/nature03838"},{"key":"2026092104150914000_2026.09.14.751546v1.45","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20084"},{"key":"2026092104150914000_2026.09.14.751546v1.46","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(19)30634-6"},{"issue":"S2","key":"2026092104150914000_2026.09.14.751546v1.47","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1017\/S1431927620021194","article-title":"\u201cAlgorithmic Advances in Single Particle Cryo-EM Data Processing Using CryoSPARC.\u201d","volume":"26","year":"2020","journal-title":"Microscopy and Microanalysis: The Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada"},{"issue":"3","key":"2026092104150914000_2026.09.14.751546v1.48","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/nmeth.4169","article-title":"cryoSPARC: Algorithms for Rapid Unsupervised Cryo-EM Structure Determination","volume":"14","year":"2017","journal-title":"Nature Methods"},{"issue":"12","key":"2026092104150914000_2026.09.14.751546v1.49","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1038\/s41592-020-00990-8","article-title":"Non-Uniform Refinement: Adaptive Regularization Improves Single-Particle Cryo-EM Reconstruction","volume":"17","year":"2020","journal-title":"Nature Methods"},{"issue":"6","key":"2026092104150914000_2026.09.14.751546v1.50","doi-asserted-by":"crossref","first-page":"115760","DOI":"10.1016\/j.celrep.2025.115760","article-title":"Designed Miniproteins Potently Inhibit and Protect against MERS-CoV","volume":"44","year":"2025","journal-title":"Cell Reports"},{"key":"2026092104150914000_2026.09.14.751546v1.51","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2003.07.013"},{"issue":"6215","key":"2026092104150914000_2026.09.14.751546v1.52","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1126\/science.1259530","article-title":"\u201cElectron Microscopy: Ultrastable Gold Substrates for Electron Cryomicroscopy","volume":"346","year":"2014","journal-title":"Science (New York, N.Y.)"},{"issue":"9","key":"2026092104150914000_2026.09.14.751546v1.53","doi-asserted-by":"crossref","first-page":"e0011617","DOI":"10.1371\/journal.pntd.0011617","article-title":"Tackling a Global Epidemic Threat: Nipah Surveillance in Bangladesh, 2006\u20132021","volume":"17","year":"2023","journal-title":"PLoS Neglected Tropical Diseases"},{"key":"2026092104150914000_2026.09.14.751546v1.54","doi-asserted-by":"publisher","DOI":"10.3390\/antib8020036"},{"key":"2026092104150914000_2026.09.14.751546v1.55","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2005.03.010"},{"issue":"11","key":"2026092104150914000_2026.09.14.751546v1.56","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1038\/s41592-019-0580-y","article-title":"Real-Time Cryo-Electron Microscopy Data Preprocessing with Warp","volume":"16","year":"2019","journal-title":"Nature Methods"},{"key":"2026092104150914000_2026.09.14.751546v1.57","first-page":"1","article-title":"\u201cGlobal and Regional Mortality Statistics of Nipah Virus from 1994 to 2023: A Comprehensive Systematic Review and Meta-Analysis.\u201d Pathogens and Global Health","volume":"20","year":"2024","journal-title":"July"},{"key":"2026092104150914000_2026.09.14.751546v1.58","doi-asserted-by":"publisher","DOI":"10.1016\/j.crmeth.2022.100172"},{"issue":"1","key":"2026092104150914000_2026.09.14.751546v1.59","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1186\/s12985-021-01652-7","article-title":"A New Hendra Virus Genotype Found in Australian Flying Foxes","volume":"18","year":"2021","journal-title":"Virology Journal"},{"issue":"6587","key":"2026092104150914000_2026.09.14.751546v1.60","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1126\/science.abm5561","article-title":"\u201cArchitecture and Antigenicity of the Nipah Virus Attachment Glycoprotein.\u201d","volume":"375","year":"2022","journal-title":"Science (New York, N.Y.)"},{"key":"2026092104150914000_2026.09.14.751546v1.61","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2122769119"},{"key":"2026092104150914000_2026.09.14.751546v1.62","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-06415-8"},{"issue":"February","key":"2026092104150914000_2026.09.14.751546v1.63","first-page":"7","article-title":"Transmission of Henipaviruses","volume":"28","year":"2018","journal-title":"Current Opinion in Virology"},{"key":"2026092104150914000_2026.09.14.751546v1.64","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003684"},{"key":"2026092104150914000_2026.09.14.751546v1.65","doi-asserted-by":"crossref","unstructured":"Zeitlin, Larry , Robert W. Cross , Courtney Woolsey , et al. 2024. \u201cTherapeutic Administration of a Cross-Reactive mAb Targeting the Fusion Glycoprotein of Nipah Virus Protects Nonhuman Primates.\u201d Science Translational Medicine 16 (741): eadl2055.","DOI":"10.1126\/scitranslmed.adl2055"},{"key":"2026092104150914000_2026.09.14.751546v1.66","doi-asserted-by":"publisher","DOI":"10.1086\/528801"},{"key":"2026092104150914000_2026.09.14.751546v1.67","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.42166"}],"container-title":[],"original-title":[],"link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.64898\/2026.09.14.751546","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T11:16:47Z","timestamp":1789989407000},"score":1,"resource":{"primary":{"URL":"http:\/\/biorxiv.org\/lookup\/doi\/10.64898\/2026.09.14.751546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,17]]},"references-count":67,"URL":"https:\/\/doi.org\/10.64898\/2026.09.14.751546","relation":{},"subject":[],"published":{"date-parts":[[2026,9,17]]},"subtype":"preprint"}}