{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"bioRxiv"}],"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:57:27Z","timestamp":1790877447032,"version":"4.1.0"},"posted":{"date-parts":[[2026,9,29]]},"group-title":"Genomics","reference-count":44,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2026,9,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                <jats:p>\n                  Genomic tools can support malaria control policy through surveillance of\n                  <jats:italic>Plasmodium falciparum<\/jats:italic>\n                  populations, tracking antimalarial drug resistance,\n                  <jats:italic>pfhrp2\/3<\/jats:italic>\n                  deletions that compromise rapid diagnostic tests, and selection at the circumsporozoite protein (PfCSP) vaccine target, as well as through molecular correction of therapeutic efficacy studies (TES). Multiplex Amplicons for Drug, Diagnostic, Diversity, and Differentiation Haplotypes using Targeted Resequencing (MAD\n                  <jats:sup>4<\/jats:sup>\n                  HatTeR), a comprehensive amplicon sequencing panel covering up to 276 targets, supports these applications but is tailored to research rather than routine programmatic use. We developed\n                  <jats:italic>P. falciparum<\/jats:italic>\n                  Public Health Amplicon Sequencing Tool (PfPHAST), a 56-target derivative of MAD\n                  <jats:sup>4<\/jats:sup>\n                  HatTeR spanning drug resistance loci,\n                  <jats:italic>pfhrp2<\/jats:italic>\n                  \/\n                  <jats:italic>3<\/jats:italic>\n                  deletion, PfCSP genotyping, non-falciparum species identification, and 20 high-heterozygosity microhaplotype loci for TES classification. We compared PfPHAST and MAD\n                  <jats:sup>4<\/jats:sup>\n                  HatTeR using laboratory strain controls, including two-strain dilution series and a five-strain mixture, across parasite densities of 100 to 10,000 parasites\/\u00b5L. At matched per-target depth, PfPHAST achieved a higher quality-control pass rate than MAD4HatTeR (94.4% versus 90.0%) and distributed reads more evenly across targets. The panels showed comparable recall and precision for drug resistance codons and microhaplotypes, reaching near-complete recall above 40% within-sample allele frequency (WSAF) at all densities, with reduced sensitivity for minor alleles below 10% WSAF at low parasite density in both panels. Observed and expected WSAF correlated strongly for both panels, and both resolved a five-strain polyclonal mixture, including a 5% minor strain. By concentrating sequencing capacity on targets of greatest programmatic relevance, PfPHAST offers a scalable, lower-cost alternative to comprehensive research panels without sacrificing performance on shared targets, complementing MAD\n                  <jats:sup>4<\/jats:sup>\n                  HatTeR for routine molecular malaria surveillance.\n                <\/jats:p>","DOI":"10.64898\/2026.09.26.754026","type":"posted-content","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:20:14Z","timestamp":1790670014000},"source":"Crossref","is-referenced-by-count":0,"title":["PfPHAST:\n                  <i>Plasmodium falciparum<\/i>\n                  Public Health Amplicon Sequencing Tool, a Streamlined Panel for Malaria Genomic Surveillance"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2258-194X","authenticated-orcid":false,"given":"Francis D.","family":"Semakuba","sequence":"first","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"National Malaria Reference and Research Laboratory (NMRRL), Central Public Health Laboratories (CPHL), Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9786-7294","authenticated-orcid":false,"given":"Bienvenu","family":"Nsengimaana","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"National Malaria Reference and Research Laboratory (NMRRL), Central Public Health Laboratories (CPHL), Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6621-0586","authenticated-orcid":false,"given":"Monica","family":"Mbabazi","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"College of Health Sciences (CHS), Makerere University, Kampala, Uganda"},{"name":"The African Center of Excellence in Bioinformatics and Data Intensive Sciences, Infectious Diseases Institute, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2002-8911","authenticated-orcid":false,"given":"Thomas","family":"Katairo","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"National Malaria Reference and Research Laboratory (NMRRL), Central Public Health Laboratories (CPHL), Kampala, Uganda"},{"name":"Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9612-2016","authenticated-orcid":false,"given":"Kathryn","family":"Murie","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California, San Francisco, California, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9639-2894","authenticated-orcid":false,"given":"Nicholas","family":"Hathaway","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California, San Francisco, California, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0819-3889","authenticated-orcid":false,"given":"Innocent","family":"Wiringilimaana","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"National Malaria Reference and Research Laboratory (NMRRL), Central Public Health Laboratories (CPHL), Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3120-6119","authenticated-orcid":false,"given":"John Vester","family":"Muwanika","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"National Malaria Reference and Research Laboratory (NMRRL), Central Public Health Laboratories (CPHL), Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kore","family":"Lum","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California, San Francisco, California, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milya","family":"Davlieva","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California, San Francisco, California, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0489-4692","authenticated-orcid":false,"given":"Victor","family":"Asua","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"National Malaria Reference and Research Laboratory (NMRRL), Central Public Health Laboratories (CPHL), Kampala, Uganda"},{"name":"Institute of Tropical Medicine, University of T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6380-4714","authenticated-orcid":false,"given":"Shahiid","family":"Kiyaga","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"The African Center of Excellence in Bioinformatics and Data Intensive Sciences, Infectious Diseases Institute, Kampala, Uganda"},{"name":"Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6469-6516","authenticated-orcid":false,"given":"Stephen","family":"Tukwasibwe","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"National Malaria Reference and Research Laboratory (NMRRL), Central Public Health Laboratories (CPHL), Kampala, Uganda"},{"name":"The African Center of Excellence in Bioinformatics and Data Intensive Sciences, Infectious Diseases Institute, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9581-0857","authenticated-orcid":false,"given":"Jackie","family":"Nakasaanya","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"National Malaria Reference and Research Laboratory (NMRRL), Central Public Health Laboratories (CPHL), Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1877-4264","authenticated-orcid":false,"given":"Karen B.","family":"Achom","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"National Malaria Reference and Research Laboratory (NMRRL), Central Public Health Laboratories (CPHL), Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6173-4006","authenticated-orcid":false,"given":"Alisen","family":"Ayitewala","sequence":"additional","affiliation":[{"name":"Central Public Health Laboratories (CPHL), Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8106-5057","authenticated-orcid":false,"given":"Jerry","family":"Mulondo","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3324-7412","authenticated-orcid":false,"given":"Eric","family":"Watyekele","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4986-8823","authenticated-orcid":false,"given":"Samuel L.","family":"Nsobya","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9106-4234","authenticated-orcid":false,"given":"Moses R.","family":"Kamya","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"The African Center of Excellence in Bioinformatics and Data Intensive Sciences, Infectious Diseases Institute, Kampala, Uganda"},{"name":"Department of Medicine, Makerere University, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4601-5171","authenticated-orcid":false,"given":"Bosco B.","family":"Agaba","sequence":"additional","affiliation":[{"name":"National Malaria Reference and Research Laboratory (NMRRL), Central Public Health Laboratories (CPHL), Kampala, Uganda"},{"name":"National Malaria Elimination Division, Ministry of Health, Kampala, Uganda"},{"name":"Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7840-5401","authenticated-orcid":false,"given":"Philip J.","family":"Rosenthal","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California, San Francisco, California, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9984-8030","authenticated-orcid":false,"given":"Melissa D.","family":"Conrad","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8605-2001","authenticated-orcid":false,"given":"Isaac","family":"Ssewanyana","sequence":"additional","affiliation":[{"name":"Infectious Diseases Research Collaboration, Kampala, Uganda"},{"name":"National Malaria Reference and Research Laboratory (NMRRL), Central Public Health Laboratories (CPHL), Kampala, Uganda"},{"name":"Central Public Health Laboratories (CPHL), Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0287-9111","authenticated-orcid":false,"given":"Bryan","family":"Greenhouse","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California, San Francisco, California, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0566-4901","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Aranda-D\u00edaz","sequence":"additional","affiliation":[{"name":"ISGlobal, Barcelona, Spain"},{"name":"Centro de Investiga\u00e7\u00e3o em Sa\u00fade de Manhi\u00e7a, Manhi\u00e7a, Mozambique"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8078-3898","authenticated-orcid":false,"given":"Jessica","family":"Briggs","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California, San Francisco, California, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"54368","reference":[{"key":"2026100109550904000_2026.09.26.754026v1.1","doi-asserted-by":"crossref","unstructured":"Krenger, P. S. et al. Probing novel epitopes on the Plasmodium falciparum circumsporozoite protein for vaccine development. Npj Vaccines 9, 225 (2024).","DOI":"10.1038\/s41541-024-01006-8"},{"key":"2026100109550904000_2026.09.26.754026v1.2","unstructured":"Africa Centres for Disease Control and Prevention. Roadmap for the Implementation of Malaria Genomic Surveillance in Africa. https:\/\/africacdc.org\/download\/roadmap-for-the-implementation-of-malaria-genomic-surveillance-in-africa\/ (2025)."},{"key":"2026100109550904000_2026.09.26.754026v1.3","unstructured":"World Health Organization. World Malaria Report 2025: Addressing the Threat of Antimalarial Drug Resistance. https:\/\/www.who.int\/publications\/i\/item\/9789240117822 (2025)."},{"key":"2026100109550904000_2026.09.26.754026v1.4","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-024-01008-2"},{"key":"2026100109550904000_2026.09.26.754026v1.5","doi-asserted-by":"crossref","unstructured":"Agaba, B. B. et al. Systematic review of the status of pfhrp2 and pfhrp3 gene deletion, approaches and methods used for its estimation and reporting in Plasmodium falciparum populations in Africa: review of published studies 2010\u20132019. Malar. J. 18, 355 (2019).","DOI":"10.1186\/s12936-019-2987-4"},{"key":"2026100109550904000_2026.09.26.754026v1.6","first-page":"225","article-title":"Malaria vaccine: WHO position paper \u2013 May 2024","volume":"19","author":"World Health Organization","year":"2024","journal-title":"Wkly. Epidemiol. Rec"},{"key":"2026100109550904000_2026.09.26.754026v1.7","unstructured":"World Health Organization. Strategy to Respond to Antimalarial Drug Resistance in Africa. https:\/\/www.who.int\/publications\/i\/item\/9789240060265 (2022)."},{"key":"2026100109550904000_2026.09.26.754026v1.8","unstructured":"World Health Organization. Methods for Surveillance of Antimalarial Drug Efficacy. https:\/\/www.who.int\/publications\/i\/item\/9789241597531."},{"key":"2026100109550904000_2026.09.26.754026v1.9","unstructured":"World Health Organization. Informal Consultation on Methodology to Distinguish Reinfection from Recrudescence in High Malaria Transmission Areas: Report of a Virtual Meeting, 17\u201318 May 2021. https:\/\/www.who.int\/publications-detail-redirect\/9789240038363 (2021)."},{"key":"2026100109550904000_2026.09.26.754026v1.10","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00159-07"},{"key":"2026100109550904000_2026.09.26.754026v1.11","first-page":"e01517","article-title":"A Computer Modelling Approach To Evaluate the Accuracy of Microsatellite Markers for Classification of Recurrent Infections during Routine Monitoring of Antimalarial Drug Efficacy","volume":"64","year":"2020","journal-title":"Antimicrob. Agents Chemother"},{"key":"2026100109550904000_2026.09.26.754026v1.12","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.119.302120"},{"key":"2026100109550904000_2026.09.26.754026v1.13","doi-asserted-by":"crossref","unstructured":"Aranda-D\u00edaz, A. et al. Sensitive and modular amplicon sequencing of Plasmodium falciparum diversity and resistance for research and public health. Sci. Rep. 15, 10737 (2025).","DOI":"10.1038\/s41598-025-94716-5"},{"key":"2026100109550904000_2026.09.26.754026v1.14","first-page":"e0006500","article-title":"Target product profiles of laboratory and data analytical frameworks for genotyping to monitor antimalarial efficacy. PLOS Glob","volume":"6","year":"2026","journal-title":"Public Health"},{"key":"2026100109550904000_2026.09.26.754026v1.15","doi-asserted-by":"crossref","first-page":"4218","DOI":"10.1038\/s41467-026-72358-z","article-title":"Continental-scale genomic surveillance of Plasmodium falciparum malaria across sub-Saharan Africa with rapid nanopore sequencing","volume":"17","year":"2026","journal-title":"Nat. Commun"},{"key":"2026100109550904000_2026.09.26.754026v1.16","doi-asserted-by":"crossref","first-page":"1509261","DOI":"10.3389\/fpara.2024.1509261","article-title":"Application of a new highly multiplexed amplicon sequencing tool to evaluate Plasmodium falciparum antimalarial resistance and relatedness in individual and pooled samples from Dschang","volume":"3","year":"2025","journal-title":"Cameroon. Front. Parasitol"},{"key":"2026100109550904000_2026.09.26.754026v1.17","unstructured":"World Health Organization. Compendium of Molecular Markers for Antimalarial Drug Resistance. (2025)."},{"key":"2026100109550904000_2026.09.26.754026v1.18","doi-asserted-by":"crossref","unstructured":"Katairo, T. et al. Performance of molecular inversion probe DR23K and Paragon MAD4HatTeR Amplicon sequencing panels for detection of Plasmodium falciparum mutations associated with antimalarial drug resistance. Malar. J. 24, 188 (2025).","DOI":"10.1186\/s12936-025-05441-3"},{"key":"2026100109550904000_2026.09.26.754026v1.19","doi-asserted-by":"publisher","DOI":"10.13028\/M2039K"},{"key":"2026100109550904000_2026.09.26.754026v1.20","doi-asserted-by":"crossref","first-page":"325","DOI":"10.12688\/wellcomeopenres.24031.1","article-title":"Pf8: an open dataset of Plasmodium falciparum genome variation in 33,325 worldwide samples","volume":"10","author":"Malaria Genomic Epidemiology Network (MalariaGEN)","year":"2025","journal-title":"Wellcome Open Res"},{"key":"2026100109550904000_2026.09.26.754026v1.21","first-page":"e00361","article-title":"Sustained high prevalence of multiple antimalarial drug resistance markers in Uganda in 2023\u20132024","volume":"70","year":"2026","journal-title":"Antimicrob. Agents Chemother"},{"key":"2026100109550904000_2026.09.26.754026v1.22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001788"},{"key":"2026100109550904000_2026.09.26.754026v1.23","doi-asserted-by":"crossref","unstructured":"Hathaway, N. J. et al. Interchromosomal segmental duplication drives translocation and loss of P. falciparum histidine-rich protein 3. eLife 13, (2024).","DOI":"10.7554\/eLife.93534"},{"key":"2026100109550904000_2026.09.26.754026v1.24","doi-asserted-by":"publisher","DOI":"10.5281\/ZENODO.21795275"},{"key":"2026100109550904000_2026.09.26.754026v1.25","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2211803)"},{"key":"2026100109550904000_2026.09.26.754026v1.26","doi-asserted-by":"publisher","DOI":"10.1101\/2024.12.31.24319821"},{"key":"2026100109550904000_2026.09.26.754026v1.27","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.18-0112"},{"key":"2026100109550904000_2026.09.26.754026v1.28","doi-asserted-by":"crossref","unstructured":"Boyce, R. M. et al. Reuse of malaria rapid diagnostic tests for amplicon deep sequencing to estimate Plasmodium falciparum transmission intensity in western Uganda. Sci. Rep. 8, 10159 (2018).","DOI":"10.1038\/s41598-018-28534-3"},{"key":"2026100109550904000_2026.09.26.754026v1.29","doi-asserted-by":"crossref","unstructured":"Schnoz, A. et al. Genotyping methods to distinguish Plasmodium falciparum recrudescence from new infection for the assessment of antimalarial drug efficacy: an observational, single-centre, comparison study. Lancet Microbe 5, (2024).","DOI":"10.1016\/S2666-5247(24)00153-8"},{"key":"2026100109550904000_2026.09.26.754026v1.30","doi-asserted-by":"crossref","unstructured":"Jo\u00e3o, M. F. et al. Geographical Heterogeneity in Antimalarial Resistance Markers by Genomic Surveillance in Angola, 2023. Am. J. Trop. Med. Hyg. 1, (2026).","DOI":"10.1101\/2025.04.08.25325242"},{"key":"2026100109550904000_2026.09.26.754026v1.31","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.25-0110"},{"key":"2026100109550904000_2026.09.26.754026v1.32","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.25-0487"},{"key":"2026100109550904000_2026.09.26.754026v1.33","doi-asserted-by":"crossref","unstructured":"Raman, J. et al. Very Low Prevalence of Validated kelch13 Mutations and Absence of Histidine-Rich Protein 2\/3 Double Gene Deletions in South African Malaria-Eliminating Districts (2022\u20132024). Am. J. Trop. Med. Hyg. 1, (2025).","DOI":"10.4269\/ajtmh.25-0204"},{"key":"2026100109550904000_2026.09.26.754026v1.34","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.24-0870"},{"key":"2026100109550904000_2026.09.26.754026v1.35","first-page":"e0005951","article-title":"Imported malaria predominates in near-elimination settings in Southwestern Uganda. PLOS Glob","volume":"6","year":"2026","journal-title":"Public Health"},{"key":"2026100109550904000_2026.09.26.754026v1.36","doi-asserted-by":"publisher","DOI":"10.64898\/2026.09.11.26362519"},{"key":"2026100109550904000_2026.09.26.754026v1.37","doi-asserted-by":"crossref","first-page":"ofag324","DOI":"10.1093\/ofid\/ofag324","article-title":"First TES in Djibouti: A Critical Milestone Amid Rising Regional Threats","volume":"13","year":"2026","journal-title":"Open Forum Infect. Dis"},{"key":"2026100109550904000_2026.09.26.754026v1.38","unstructured":"National Health Laboratory and Diagnostic Services, Uganda. Strengthening Africa\u2019s Response to Malaria Through Molecular Surveillance. News & announcements https:\/\/cphl.go.ug\/news?article=strengthening-africas-response-malaria-through-molecular-surveillance."},{"key":"2026100109550904000_2026.09.26.754026v1.39","unstructured":"Resources | EPPIcenter. https:\/\/eppicenter.ucsf.edu\/resources."},{"key":"2026100109550904000_2026.09.26.754026v1.40","unstructured":"eppicenter. wonderland-docs. https:\/\/eppicenter.github.io\/wonderland-docs\/."},{"key":"2026100109550904000_2026.09.26.754026v1.41","first-page":"273","article-title":"Malaria on Terra: A Shared Infrastructure for Malaria Genomic Surveillance and Research [version 1]","volume":"3","author":"Malaria on Terra Development Team","year":"2026","journal-title":"VeriXiv"},{"key":"2026100109550904000_2026.09.26.754026v1.42","unstructured":"EPPIcenter\/copy-number-variation. EPPIcenter (2026)."},{"key":"2026100109550904000_2026.09.26.754026v1.43","doi-asserted-by":"publisher","DOI":"10.1101\/2025.07.30.667738"},{"key":"2026100109550904000_2026.09.26.754026v1.44","doi-asserted-by":"publisher","DOI":"10.64898\/2026.06.04.26354343"}],"container-title":[],"original-title":[],"link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.64898\/2026.09.26.754026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:06:39Z","timestamp":1790874399000},"score":1,"resource":{"primary":{"URL":"http:\/\/biorxiv.org\/lookup\/doi\/10.64898\/2026.09.26.754026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,29]]},"references-count":44,"URL":"https:\/\/doi.org\/10.64898\/2026.09.26.754026","relation":{},"subject":[],"published":{"date-parts":[[2026,9,29]]},"subtype":"preprint"}}