{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:04:05Z","timestamp":1785416645132,"version":"3.56.0"},"reference-count":0,"publisher":"Caleo","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Endod J"],"abstract":"<jats:p>Objective: This study evaluated the influence of initial periapical lesion size and the use of bone graft and\/or membrane materials on endodontic microsurgery outcomes, considering other clinical factors.\r\nMethods: A retrospective cohort study included 127 teeth treated with endodontic microsurgery, with or without adjunctive bone graft and\/or membrane placement, between January 2021 and December 2024. Based on the initial Periapical Index (PAI) scores, patients were classified into 2 groups: small lesions (PAI \u22643) and large lesions (LL, PAI \u2265 4). Treatment outcomes were assessed at 12 months according to established criteria. Statistical analyses included chi-square or Fisher\u2019s exact tests, t-tests and multivariate logistic regression (P &lt; .05).\r\nResults: The overall success rate was 64.6%. The use of bone graft and\/or membrane was associated with significantly higher success rates (72.0% vs. 53.8%; odds ratio [OR]=2.34, 95% CI: 1.10-4.98; P=.03), particularlyin LLs (69.6% vs. 42.3%; OR=2.90, 95% CI: 1.08-7.78; P = .03). In multivariate analysis, regenerative material use(adjusted OR=2.48, 95% CI: 1.12-5.50; P=.03) and anterior tooth position (adjusted OR=2.71, 95% CI: 1.24-5.93; P=.01) were significantly associated with treatment success.\r\nConclusion: Within the limitations of this 12-month retrospective cohort study, the adjunctive use of regenerative materials and anterior tooth position were associated with higher success rates in endodontic micro-surgery. Preoperative lesion size alone was not significantly associated with treatment success.<\/jats:p>","DOI":"10.65717\/eej.2026.26044","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T12:34:58Z","timestamp":1785414898000},"source":"Crossref","is-referenced-by-count":0,"title":["Periapical Lesion Size and Regenerative Materials as Prognostic Factors in Endodontic Microsurgery: A 12-Month Retrospective Cohort Study"],"prefix":"10.65717","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6976-0743","authenticated-orcid":false,"given":"Ji-Yun","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3165-2592","authenticated-orcid":false,"given":"Bokyung","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1192-7066","authenticated-orcid":false,"given":"Jeong-Kui","family":"Ku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5634-5054","authenticated-orcid":false,"given":"Ji-Young","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"55248","published-online":{"date-parts":[[2026,7,30]]},"container-title":["European Endodontic Journal"],"original-title":[],"link":[{"URL":"https:\/\/eurendodj.com\/index.php\/pub\/article\/download\/427\/453","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eurendodj.com\/index.php\/pub\/article\/download\/427\/453","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T12:34:58Z","timestamp":1785414898000},"score":1,"resource":{"primary":{"URL":"https:\/\/eurendodj.com\/index.php\/pub\/article\/view\/427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.65717\/eej.2026.26044","relation":{},"ISSN":["2548-0839"],"issn-type":[{"value":"2548-0839","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,30]]}}}