{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:47:23Z","timestamp":1791816443996,"version":"4.3.4"},"reference-count":0,"publisher":"Caleo","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Adv Otol"],"abstract":"<jats:p>To evaluate the effectiveness of laser-assisted cholesteatoma surgery compared with conventional techniques, with a focus on residual disease, postoperative complications, and hearing preservation.\r\nA systematic review and meta-analysis were conducted following PRISMA guidelines. Databases were searched for studies comparing laser and non-laser cholesteatoma surgery. Eligible studies were screened, and risk ratios (RR) with 95% CI were calculated using a random-effects model.\r\nThree studies including 271 participants reported residual disease outcomes. The pooled risk ratio was RR = 0.53; 95% CI, 0.12-2.39; P = .406, indicating no statistically significant difference between laser and non-laser groups. Moderate heterogeneity was observed (I2 = 63.5%). Only 1 study reported postoperative complications, with RR = 1.04; 95% CI, 0.18-5.97. A subgroup analysis from 1 study compared laser myringotomy with endaural laser-assisted single-stage inside-out cholesteatoma, showing RR = 0.57; 95% CI, 0.15-2.19.\r\nLaser-assisted cholesteatoma surgery demonstrates comparable rates of residual disease and complications to conventional surgery. While lasers\r\nmay offer technical advantages, current evidence is limited and underpowered. Larger, high-quality trials are needed to clarify their role in cholesteatoma\r\nmanagement.<\/jats:p>","DOI":"10.65717\/iao.2026.262322","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:10:41Z","timestamp":1791814241000},"page":"1-6","source":"Crossref","is-referenced-by-count":0,"title":["The Application of Laser Technology in Cholesteatoma Surgery: Systematic Review and Meta-analysis"],"prefix":"10.65717","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6920-5189","authenticated-orcid":false,"given":"Amenah","family":"Al Manasef","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-4453-0992","authenticated-orcid":false,"given":"Amer","family":"Alsulaymi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0773-4555","authenticated-orcid":false,"given":"Aryam","family":"Althobaiti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4434-985X","authenticated-orcid":false,"given":"Faisal","family":"Al-Dhafeeri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0259-0972","authenticated-orcid":false,"given":"Lamar","family":"Fatani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8120-0246","authenticated-orcid":false,"given":"Mohammad","family":"Bawazir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3571-4224","authenticated-orcid":false,"given":"Munira","family":"Albeshr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6030-0884","authenticated-orcid":false,"given":"Nawaf","family":"Alrabie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5878-0617","authenticated-orcid":false,"given":"Rawan","family":"Almutairi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3891-4820","authenticated-orcid":false,"given":"Sufian","family":"Alsweed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5359-7096","authenticated-orcid":false,"given":"Thikra","family":"Alsenani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2905-358X","authenticated-orcid":false,"given":"Ziad","family":"Abdullah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2512-407X","authenticated-orcid":false,"given":"Faisal","family":"Zawawi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"55248","published-online":{"date-parts":[[2026,10,12]]},"container-title":["The Journal of International Advanced Otology"],"original-title":[],"link":[{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/2029\/2208","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/download\/2029\/2208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:10:42Z","timestamp":1791814242000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.advancedotology.org\/index.php\/pub\/article\/view\/2029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,12]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,9,21]]}},"URL":"https:\/\/doi.org\/10.65717\/iao.2026.262322","relation":{},"ISSN":["2148-3817"],"issn-type":[{"value":"2148-3817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,12]]}}}