{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T22:07:48Z","timestamp":1789250868468,"version":"build-2803163510"},"reference-count":0,"publisher":"Association of Paediatric Surgeons of Nigeria","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["afr j paedsurg"],"abstract":"<jats:p>Background: Choledochal cysts are congenital anomalies of the bile ducts that can lead to significant complications, such as cholangitis, liver fibrosis, and biliary obstruction. This study aims to evaluate the effectiveness and safety of percutaneous transhepatic biliary drainage (PTBD) in managing choledochal cysts with cholangitis in children.\r\nMethods: This non-randomized interventional study included twelve pediatric patients with choledochal cysts and cholangitis treated over two years. PTBD was performed to relieve biliary obstruction and stabilize patients before definitive surgical repair. Data were collected on patient demographics, clinical presentation, hematological and biochemical profiles, imaging findings, procedural details, and outcomes.\r\nResults: A total of 12 patients were included (median age: 24 months, 75% female). Common symptoms were jaundice (83.3%), abdominal pain (75%), and fever (66.7%). Baseline bilirubin and liver enzymes were elevated in all cases. Following PTBD bilirubin levels decreased by 56% (median) by day 7, with 90% symptom resolution. Eight patients proceeded to surgery, while three had unfavorable outcomes. No major PTBD-related complications occurred. At follow-up, all surgically treated patients had normalized liver function, with histopathology showing periportal fibrosis in 50% of cases.\r\nConclusion: PTBD improved preoperative stability and liver function, facilitating safer surgical correction. PTBD was associated with clinical and biochemical stabilization in selected high-risk patients and may serve as an interim strategy before definitive surgery. Larger controlled studies are required to clarify its impact on outcomes. \u00a0<\/jats:p>","DOI":"10.67481\/ajps.v23i1.883","type":"journal-article","created":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T21:45:09Z","timestamp":1789249509000},"page":"7-14","source":"Crossref","is-referenced-by-count":0,"title":["Exploring the Role of Percutaneous Transhepatic Biliary Drainage in the Interim Management of Pediatric Choledochal Cysts with Cholangitis"],"prefix":"10.67481","volume":"23","author":[{"given":"Rashi","family":"Rashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit Kumar","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bindey","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajeev Nayan","family":"Priyadarshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"57241","published-online":{"date-parts":[[2026,9,12]]},"container-title":["African Journal of Paediatric Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.afrjpaedsurg.com\/index.php\/ajps\/article\/download\/883\/1100","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.afrjpaedsurg.com\/index.php\/ajps\/article\/download\/883\/1100","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T21:45:10Z","timestamp":1789249510000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.afrjpaedsurg.com\/index.php\/ajps\/article\/view\/883"}},"subtitle":["A Pilot Study"],"short-title":[],"issued":{"date-parts":[[2026,9,12]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,9,12]]}},"URL":"https:\/\/doi.org\/10.67481\/ajps.v23i1.883","relation":{},"ISSN":["0974-5998","0189-6725"],"issn-type":[{"value":"0974-5998","type":"electronic"},{"value":"0189-6725","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9,12]]}}}