{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:09:02Z","timestamp":1788221342843,"version":"build-2803163510"},"reference-count":25,"publisher":"Japan Surgical Society","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Surg Case Rep"],"published-print":{"date-parts":[[2025]]},"DOI":"10.70352\/scrj.cr.25-0096","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T22:09:11Z","timestamp":1749506951000},"page":"n\/a","source":"Crossref","is-referenced-by-count":1,"title":["Malignant Triton Tumor of the Ileocolic Mesentery with Neurofibromatosis Type 1: A Case Report and Literature Review"],"prefix":"10.70352","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8953-8920","authenticated-orcid":false,"given":"Kenichi","family":"Ishibayashi","sequence":"first","affiliation":[{"name":"Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Kitamura","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sho","family":"Tsuyama","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akane","family":"Yoshikawa","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maika","family":"Zasu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Ikku","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Asakawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuya","family":"Gunjikake","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosuke","family":"Kito","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahisa","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinao","family":"Ohbatake","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiro","family":"Terai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuyoshi","family":"Katayanagi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Kadoya","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Minato","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Bando","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"51119","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Stasik CJ, Tawfik O. Malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differentiation (malignant triton tumor). Arch Pathol Lab Med 2006; 130: 1878\u201381.","DOI":"10.5858\/2006-130-1878-MPNSTW"},{"key":"2","unstructured":"2) Yakulis R, Manack L, Murphy AI Jr. Postradiation malignant triton tumor. A case report and review of the literature. Arch Pathol Lab Med 1996; 120: 541\u20138."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Brooks JS, Freeman M, Enterline HT. Malignant \u201cTriton\u201d tumors. Natural history and immunohistochemistry of nine new cases with literature review. Cancer 1985; 55: 2543\u20139.","DOI":"10.1002\/1097-0142(19850601)55:11<2543::AID-CNCR2820551105>3.0.CO;2-4"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Woodruff JM, Chernik NL, Smith MC, et al. Peripheral nerve tumors with rhabdomyosarcomatous differentiation (malignant \u201cTriton\u201d tumors). Cancer 1973; 32: 426\u201339.","DOI":"10.1002\/1097-0142(197308)32:2<426::AID-CNCR2820320221>3.0.CO;2-W"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Rekhi B, Jambhekar NA, Puri A, et al. Clinicomorphologic features of a series of 10 cases of malignant triton tumors diagnosed over 10 years at a tertiary cancer hospital in Mumbai, India. Ann Diagn Pathol 2008; 12: 90\u20137.","DOI":"10.1016\/j.anndiagpath.2007.04.010"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Asahi Y, Nakagawa T, Nakanishi K, et al. Malignant triton tumor of the duodenum: report of a case. Int Cancer Conf J 2018; 7: 52\u20138.","DOI":"10.1007\/s13691-018-0320-7"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Hoshimoto S, Morise Z, Takeura C, et al. Malignant Triton tumor in the retroperitoneal space associated with neurofibromatosis type 1: a case study. Rare Tumors 2009; 1: e27.","DOI":"10.4081\/rt.2009.e27"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Nirhale DS, Parasnis A, Bora C, et al. Retroperitoneal peripheral nerve sheath tumour of triton type-a case report. Indian J Surg 2013; 75: 12\u20134.","DOI":"10.1007\/s12262-011-0300-z"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Li Z, Xiang J, Yan S, et al. Malignant triton tumor of the retroperitoneum: a case report and review of the literature. World J Surg Oncol 2012; 10: 96.","DOI":"10.1186\/1477-7819-10-96"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Mijovi\u0107 Z, Mihailovi\u0107 D, Zivkovi\u0107 N, et al. A rare case of retroperitoneal malignant Triton tumor invading renal vein and small intestine. Vojnosanit Pregl 2013; 70: 322\u20135.","DOI":"10.2298\/VSP1303322M"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Bian Y, Yongbo X, Xi Z, et al. A series of 10 malignant triton tumors in one institution. Medicine (Baltimore) 2019; 98: e16797.","DOI":"10.1097\/MD.0000000000016797"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Hou Z, Wang C, Li L, et al. Retroperitoneal malignant triton tumor in an infant: a case report and literature review. Transl Pediatr 2020; 9: 567\u201372.","DOI":"10.21037\/tp.2020.03.12"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Liu M, Bian J. Malignant Triton tumor of the retroperitoneum in a male unaffected by neurofibromatosis 1: a case report and literature review. Asian J Surg 2022; 45: 2766\u20138.","DOI":"10.1016\/j.asjsur.2022.06.030"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Chaudhry I, Algazal T, Cheema A, et al. Mediastinal malignant triton tumor: a rare case series and review of literature. Int J Surg Case Rep 2019; 62: 115\u20139.","DOI":"10.1016\/j.ijscr.2019.08.020"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Aldlyami E, Dramis A, Grimer RJ, et al. Malignant triton tumour of the thigh-a retrospective analysis of nine cases. Eur J Surg Oncol 2006; 32: 808\u201310.","DOI":"10.1016\/j.ejso.2006.04.008"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Evans DG, Howard E, Giblin C, et al. Birth incidence and prevalence of tumor-prone syndromes: estimates from a UK family genetic register service. Am J Med Genet A 2010; 152A: 327\u201332.","DOI":"10.1002\/ajmg.a.33139"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Rasmussen SA, Yang Q, Friedman JM. Mortality in neurofibromatosis 1: an analysis using U.S. death certificates. Am J Hum Genet 2001; 68: 1110\u20138.","DOI":"10.1086\/320121"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Fern\u00e1ndez-Medarde A, Santos E. Ras in cancer and developmental diseases. Genes Cancer 2011; 2: 344\u201358.","DOI":"10.1177\/1947601911411084"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Yap YS, McPherson JR, Ong CK, et al. The NF1 gene revisited - from bench to bedside. Oncotarget 2014; 5: 5873\u201392.","DOI":"10.18632\/oncotarget.2194"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Rasmussen SA, Friedman JM. NF1 gene and neurofibromatosis 1. Am J Epidemiol 2010; 151: 33\u201340.","DOI":"10.1093\/oxfordjournals.aje.a010118"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Kamran SC, Howard SA, Shinagare AB, et al. Malignant peripheral nerve sheath tumors: prognostic impact of rhabdomyoblastic differentiation (malignant triton tumors), neurofibromatosis 1 status and location. Eur J Surg Oncol 2013; 39: 46\u201352.","DOI":"10.1016\/j.ejso.2012.09.001"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Mussi C, Schildhaus HU, Gronchi A, et al. Therapeutic consequences from molecular biology for gastrointestinal stromal tumor patients affected by neurofibromatosis type 1. Clin Cancer Res 2008; 14: 4550\u20135.","DOI":"10.1158\/1078-0432.CCR-08-0086"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Judson I, Verweij J, Gelderblom H, et al. Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial. Lancet Oncol 2014; 15: 415\u201323.","DOI":"10.1016\/S1470-2045(14)70063-4"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) von Mehren M, Kane JM, Agulnik M, et al. Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw 2022; 20: 815\u201333.","DOI":"10.6004\/jnccn.2022.0035"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Wagner MJ, Amodu LI, Duh MS, et al. A retrospective chart review of drug treatment patterns and clinical outcomes among patients with metastatic or recurrent soft tissue sarcoma refractory to one or more prior chemotherapy treatments. BMC Cancer 2015; 15: 175.","DOI":"10.1186\/s12885-015-1182-4"}],"container-title":["Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/scrj\/11\/1\/11_cr.25-0096\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,14]],"date-time":"2025-06-14T04:29:07Z","timestamp":1749875347000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/scrj\/11\/1\/11_cr.25-0096\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.70352\/scrj.cr.25-0096","relation":{},"ISSN":["2198-7793"],"issn-type":[{"value":"2198-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"cr.25-0096"}}